Immune-epithelial crosstalk governs immune checkpoint inhibitor efficacy in colorectal cancer.

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Title: Immune-epithelial crosstalk governs immune checkpoint inhibitor efficacy in colorectal cancer.
Authors: Lee SL; School of Cancer Sciences, University of Southampton, Tremona Road, Southampton, UK.; University Hospital Southampton NHS Foundation Trust, Tremona Road, Southampton, UK., Bateman AC; University Hospital Southampton NHS Foundation Trust, Tremona Road, Southampton, UK., Ashton-Key M; University Hospital Southampton NHS Foundation Trust, Tremona Road, Southampton, UK., Primrose JN; School of Cancer Sciences, University of Southampton, Tremona Road, Southampton, UK.; University Hospital Southampton NHS Foundation Trust, Tremona Road, Southampton, UK., Mirnezami A; School of Cancer Sciences, University of Southampton, Tremona Road, Southampton, UK.; University Hospital Southampton NHS Foundation Trust, Tremona Road, Southampton, UK., Al-Shamkhani A; Antibody and Vaccine Group, Faculty of Medicine, School of Cancer Sciences, Centre for Cancer Immunology, University of Southampton, Southampton, UK., Thirdborough SM; Antibody and Vaccine Group, Faculty of Medicine, School of Cancer Sciences, Centre for Cancer Immunology, University of Southampton, Southampton, UK.
Source: IScience [iScience] 2026 Jul 08; Vol. 29 (7), pp. 116544. Date of Electronic Publication: 2026 Jul 08 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE
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  Data: Immune-epithelial crosstalk governs immune checkpoint inhibitor efficacy in colorectal cancer.
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  Data: <searchLink fieldCode="AU" term="%22Lee+SL%22">Lee SL</searchLink>; School of Cancer Sciences, University of Southampton, Tremona Road, Southampton, UK.; University Hospital Southampton NHS Foundation Trust, Tremona Road, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Bateman+AC%22">Bateman AC</searchLink>; University Hospital Southampton NHS Foundation Trust, Tremona Road, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Ashton-Key+M%22">Ashton-Key M</searchLink>; University Hospital Southampton NHS Foundation Trust, Tremona Road, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Primrose+JN%22">Primrose JN</searchLink>; School of Cancer Sciences, University of Southampton, Tremona Road, Southampton, UK.; University Hospital Southampton NHS Foundation Trust, Tremona Road, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Mirnezami+A%22">Mirnezami A</searchLink>; School of Cancer Sciences, University of Southampton, Tremona Road, Southampton, UK.; University Hospital Southampton NHS Foundation Trust, Tremona Road, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Al-Shamkhani+A%22">Al-Shamkhani A</searchLink>; Antibody and Vaccine Group, Faculty of Medicine, School of Cancer Sciences, Centre for Cancer Immunology, University of Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Thirdborough+SM%22">Thirdborough SM</searchLink>; Antibody and Vaccine Group, Faculty of Medicine, School of Cancer Sciences, Centre for Cancer Immunology, University of Southampton, Southampton, UK.
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  Data: <searchLink fieldCode="JN" term="%22101724038%22">IScience</searchLink> [iScience] 2026 Jul 08; Vol. 29 (7), pp. 116544. <i>Date of Electronic Publication: </i>2026 Jul 08 (<i>Print Publication: </i>2026).
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        Value: 10.1016/j.isci.2026.116544
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        Text: English
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      – TitleFull: Immune-epithelial crosstalk governs immune checkpoint inhibitor efficacy in colorectal cancer.
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              Text: 2026 Jul 08
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              Y: 2026
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