The β1 adrenoceptor (AR) blocker metoprolol normalises βAR cascade and caveolar protein expression and restores β1AR responsiveness in failing right ventricular myocytes.

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Title: The β1 adrenoceptor (AR) blocker metoprolol normalises βAR cascade and caveolar protein expression and restores β1AR responsiveness in failing right ventricular myocytes.
Authors: Norman R; School of Biomedical Sciences, Faculty of Biological Sciences, University of Leeds, UK., Stones R; School of Biomedical Sciences, Faculty of Biological Sciences, University of Leeds, UK., Power AS; Department of Physiology, University of Auckland, Auckland, New Zealand., White E; School of Biomedical Sciences, Faculty of Biological Sciences, University of Leeds, UK., Calaghan SC; School of Biomedical Sciences, Faculty of Biological Sciences, University of Leeds, UK., Fowler ED; School of Biosciences, College of Biological and Life Sciences, University of Cardiff, Cardiff, UK.
Source: Journal of molecular and cellular cardiology plus [J Mol Cell Cardiol Plus] 2026 Jul 17; Vol. 17, pp. 100857. Date of Electronic Publication: 2026 Jul 17 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Elsevier, Inc Country of Publication: England NLM ID: 9918470779706676 Publication Model: eCollection Cited Medium: Internet ISSN: 2772-9761 (Electronic) Linking ISSN: 27729761 NLM ISO Abbreviation: J Mol Cell Cardiol Plus Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2772-9761
DOI:10.1016/j.jmccpl.2026.100857