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ACSS2 is required for colorectal cancer progression and a druggable target for colorectal cancer treatment.

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Title: ACSS2 is required for colorectal cancer progression and a druggable target for colorectal cancer treatment.
Authors: Wang L; Department of Medicine, Division of Biological Sciences, The University of Chicago, Chicago, IL, USA., Dougherty U; Department of Medicine, Division of Biological Sciences, The University of Chicago, Chicago, IL, USA., He W; Department of Medicine, Division of Biological Sciences, The University of Chicago, Chicago, IL, USA., Gao L; Department of Medicine, Division of Biological Sciences, The University of Chicago, Chicago, IL, USA., Muefong C; Department of Medicine, Division of Biological Sciences, The University of Chicago, Chicago, IL, USA., Sarkar R; Department of Medicine, Division of Biological Sciences, The University of Chicago, Chicago, IL, USA., Du J; Department of Medicine, Division of Biological Sciences, The University of Chicago, Chicago, IL, USA., Shergill A; Department of Medicine, Division of Biological Sciences, The University of Chicago, Chicago, IL, USA., Lin H; Department of Medicine, Division of Biological Sciences, The University of Chicago, Chicago, IL, USA.; Department of Chemistry, Division of Biological Sciences, The University of Chicago, Chicago, IL, USA.; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA., Bissonnette M; Department of Medicine, Division of Biological Sciences, The University of Chicago, Chicago, IL, USA., Li YC; Department of Medicine, Division of Biological Sciences, The University of Chicago, Chicago, IL, USA.; Committee on Molecular Metabolism and Nutrition, The University of Chicago, Chicago, IL, USA.
Source: IScience [iScience] 2026 Jul 21; Vol. 29 (8), pp. 116860. Date of Electronic Publication: 2026 Jul 21 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE
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  Data: ACSS2 is required for colorectal cancer progression and a druggable target for colorectal cancer treatment.
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  Data: <searchLink fieldCode="AU" term="%22Wang+L%22">Wang L</searchLink>; Department of Medicine, Division of Biological Sciences, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Dougherty+U%22">Dougherty U</searchLink>; Department of Medicine, Division of Biological Sciences, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22He+W%22">He W</searchLink>; Department of Medicine, Division of Biological Sciences, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Gao+L%22">Gao L</searchLink>; Department of Medicine, Division of Biological Sciences, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Muefong+C%22">Muefong C</searchLink>; Department of Medicine, Division of Biological Sciences, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Sarkar+R%22">Sarkar R</searchLink>; Department of Medicine, Division of Biological Sciences, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Du+J%22">Du J</searchLink>; Department of Medicine, Division of Biological Sciences, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Shergill+A%22">Shergill A</searchLink>; Department of Medicine, Division of Biological Sciences, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Lin+H%22">Lin H</searchLink>; Department of Medicine, Division of Biological Sciences, The University of Chicago, Chicago, IL, USA.; Department of Chemistry, Division of Biological Sciences, The University of Chicago, Chicago, IL, USA.; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Bissonnette+M%22">Bissonnette M</searchLink>; Department of Medicine, Division of Biological Sciences, The University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Li+YC%22">Li YC</searchLink>; Department of Medicine, Division of Biological Sciences, The University of Chicago, Chicago, IL, USA.; Committee on Molecular Metabolism and Nutrition, The University of Chicago, Chicago, IL, USA.
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  Data: <searchLink fieldCode="JN" term="%22101724038%22">IScience</searchLink> [iScience] 2026 Jul 21; Vol. 29 (8), pp. 116860. <i>Date of Electronic Publication: </i>2026 Jul 21 (<i>Print Publication: </i>2026).
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101724038 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>2589-0042 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2225890042%22">25890042 </searchLink><i>NLM ISO Abbreviation: </i>iScience <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1016/j.isci.2026.116860
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              Text: 2026 Jul 21
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