Setmelanotide alleviates diabetes-associated cognitive impairment by interrupting the binding of ICAM-1 and JIP1 in endothelial cells of the blood-brain barrier.
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| Title: | Setmelanotide alleviates diabetes-associated cognitive impairment by interrupting the binding of ICAM-1 and JIP1 in endothelial cells of the blood-brain barrier. |
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| Authors: | Wu SD; The Graduate School, Xuzhou Medical University, Xuzhou, Jiangsu, 221004, China., Wang X; The Graduate School, Xuzhou Medical University, Xuzhou, Jiangsu, 221004, China., Zhou YM; The Graduate School, Xuzhou Medical University, Xuzhou, Jiangsu, 221004, China., Hu B; Jiangsu Key Laboratory of Brain Disease and Bioinformation, Research Center for Biochemistry and Molecular Biology, Xuzhou Medical University, Xuzhou, Jiangsu, 221004, China., Wang KY; The Graduate School, Xuzhou Medical University, Xuzhou, Jiangsu, 221004, China., Yan CJ; The Graduate School, Xuzhou Medical University, Xuzhou, Jiangsu, 221004, China., Zhu HY; The Graduate School, Xuzhou Medical University, Xuzhou, Jiangsu, 221004, China., Li H; Jiangsu Key Laboratory of Brain Disease and Bioinformation, Research Center for Biochemistry and Molecular Biology, Xuzhou Medical University, Xuzhou, Jiangsu, 221004, China., Wang XC; Department of Neurosurgery, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, 221002, China., Wang HP; Jiangsu Engineering Center for Precision Diagnosis and Treatment Research of Polygenic Diseases, Key Laboratory of Genetic Foundation and Clinical Application, Department of Genetics, Xuzhou Medical University, Xuzhou, 221004, China., Cheng AF; Department of Biomedical Sciences, Faculty of Health Sciences, University of Macau, Taipa, Macao, SAR, 999078, China., Zhu ZS; Jiangsu Engineering Center for Precision Diagnosis and Treatment Research of Polygenic Diseases, Key Laboratory of Genetic Foundation and Clinical Application, Department of Genetics, Xuzhou Medical University, Xuzhou, 221004, China. Electronic address: victorzhu2013@xzhmu.edu.cn., Ying CJ; Jiangsu Engineering Center for Precision Diagnosis and Treatment Research of Polygenic Diseases, Key Laboratory of Genetic Foundation and Clinical Application, Department of Genetics, Xuzhou Medical University, Xuzhou, 221004, China; Department of Endocrinology, Affiliated Hospital of Xuzhou Medical University, Xuzhou, Jiangsu, 221002, China.. Electronic address: ycj321651@163.com., Zhou XY; Jiangsu Engineering Center for Precision Diagnosis and Treatment Research of Polygenic Diseases, Key Laboratory of Genetic Foundation and Clinical Application, Department of Genetics, Xuzhou Medical University, Xuzhou, 221004, China. Electronic address: zhouxiaoyan0201@xzhmu.edu.cn. |
| Source: | Metabolism: clinical and experimental [Metabolism] 2026 Jul 24, pp. 156712. Date of Electronic Publication: 2026 Jul 24. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Inc Country of Publication: United States NLM ID: 0375267 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-8600 (Electronic) Linking ISSN: 00260495 NLM ISO Abbreviation: Metabolism Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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