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Plasma LC-HRMS metabolomics in parkinsonian syndromes: comparative evaluation of sample preparation protocols for exploratory metabolic signatures.

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Title: Plasma LC-HRMS metabolomics in parkinsonian syndromes: comparative evaluation of sample preparation protocols for exploratory metabolic signatures.
Authors: Esposito E; IRCCS, Istituto Delle Scienze Neurologiche di Bologna, Laboratorio di Proteomica Metabolomica e Chimica Bioanalitica, Bologna, Italy., Perrone A; Centre for Applied Biomedical Research (CRBA), University of Bologna, Bologna, Italy., Lopane G; IRCCS Istituto Delle Scienze Neurologiche di Bologna, Unit of Rehabilitation Medicine, Bologna, Italy., Vitagliano R; IRCCS, Istituto Delle Scienze Neurologiche di Bologna, Laboratorio di Proteomica Metabolomica e Chimica Bioanalitica, Bologna, Italy., Interino N; IRCCS, Istituto Delle Scienze Neurologiche di Bologna, Laboratorio di Proteomica Metabolomica e Chimica Bioanalitica, Bologna, Italy., Caravelli A; IRCCS, Istituto Delle Scienze Neurologiche di Bologna, Laboratorio di Proteomica Metabolomica e Chimica Bioanalitica, Bologna, Italy., Cancellerini C; Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy., Calandra-Buonaura G; Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.; IRCCS Istituto Delle Scienze Neurologiche di Bologna, UOC Clinica Neurologica Rete Metropolitana NEUROMET, Bologna, Italy., Fiori J; IRCCS, Istituto Delle Scienze Neurologiche di Bologna, Laboratorio di Proteomica Metabolomica e Chimica Bioanalitica, Bologna, Italy. jessica.fiori@unibo.it.; Department of Chemistry 'G. Ciamician', University of Bologna, Bologna, Italy. jessica.fiori@unibo.it., Contin M; IRCCS, Istituto Delle Scienze Neurologiche di Bologna, Laboratorio di Proteomica Metabolomica e Chimica Bioanalitica, Bologna, Italy.; Department of Biomedical and Neuromotor Sciences, University of Bologna, Bologna, Italy.
Source: Analytical and bioanalytical chemistry [Anal Bioanal Chem] 2026 Jul 24. Date of Electronic Publication: 2026 Jul 24.
Publication Type: Journal Article
Journal Info: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 101134327 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1618-2650 (Electronic) Linking ISSN: 16182642 NLM ISO Abbreviation: Anal Bioanal Chem Subsets: MEDLINE
Database: MEDLINE Ultimate
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              Text: 2026 Jul 24
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