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Spatial proteomic analysis of antimicrobial therapeutic-releasing intracortical probes as a platform technology to modulate specific neuroinflammatory pathways.

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Title: Spatial proteomic analysis of antimicrobial therapeutic-releasing intracortical probes as a platform technology to modulate specific neuroinflammatory pathways.
Authors: Burkhart G; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA. jrc35@case.edu.; Advanced Platform Technology Center, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH 44106, USA., Wang JJ; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA. jrc35@case.edu.; Advanced Platform Technology Center, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH 44106, USA., Gao Y; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA. jrc35@case.edu., Glusauskas G; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA. jrc35@case.edu.; Advanced Platform Technology Center, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH 44106, USA., Thompson A; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA. jrc35@case.edu.; Advanced Platform Technology Center, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH 44106, USA., Newman L; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA. jrc35@case.edu., Pancrazio JJ; Department of Bioengineering, The University of Texas at Dallas, Richardson, TX 75080, USA., von Recum HA; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA. jrc35@case.edu.; Advanced Platform Technology Center, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH 44106, USA., Hess-Dunning A; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA. jrc35@case.edu.; Advanced Platform Technology Center, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH 44106, USA., Hamedani HA; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA. jrc35@case.edu.; Department of Materials Science and Engineering, Case Western Reserve University, Cleveland, OH, USA., Capadona JR; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA. jrc35@case.edu.; Advanced Platform Technology Center, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH 44106, USA.
Source: Journal of materials chemistry. B [J Mater Chem B] 2026 Jul 27. Date of Electronic Publication: 2026 Jul 27.
Publication Type: Journal Article
Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101598493 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2050-7518 (Electronic) Linking ISSN: 2050750X NLM ISO Abbreviation: J Mater Chem B Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Burkhart+G%22">Burkhart G</searchLink>; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA. jrc35@case.edu.; Advanced Platform Technology Center, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH 44106, USA.<br /><searchLink fieldCode="AU" term="%22Wang+JJ%22">Wang JJ</searchLink>; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA. jrc35@case.edu.; Advanced Platform Technology Center, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH 44106, USA.<br /><searchLink fieldCode="AU" term="%22Gao+Y%22">Gao Y</searchLink>; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA. jrc35@case.edu.<br /><searchLink fieldCode="AU" term="%22Glusauskas+G%22">Glusauskas G</searchLink>; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA. jrc35@case.edu.; Advanced Platform Technology Center, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH 44106, USA.<br /><searchLink fieldCode="AU" term="%22Thompson+A%22">Thompson A</searchLink>; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA. jrc35@case.edu.; Advanced Platform Technology Center, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH 44106, USA.<br /><searchLink fieldCode="AU" term="%22Newman+L%22">Newman L</searchLink>; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA. jrc35@case.edu.<br /><searchLink fieldCode="AU" term="%22Pancrazio+JJ%22">Pancrazio JJ</searchLink>; Department of Bioengineering, The University of Texas at Dallas, Richardson, TX 75080, USA.<br /><searchLink fieldCode="AU" term="%22von+Recum+HA%22">von Recum HA</searchLink>; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA. jrc35@case.edu.; Advanced Platform Technology Center, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH 44106, USA.<br /><searchLink fieldCode="AU" term="%22Hess-Dunning+A%22">Hess-Dunning A</searchLink>; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA. jrc35@case.edu.; Advanced Platform Technology Center, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH 44106, USA.<br /><searchLink fieldCode="AU" term="%22Hamedani+HA%22">Hamedani HA</searchLink>; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA. jrc35@case.edu.; Department of Materials Science and Engineering, Case Western Reserve University, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Capadona+JR%22">Capadona JR</searchLink>; Department of Biomedical Engineering, Case Western Reserve University, Cleveland, OH 44106, USA. jrc35@case.edu.; Advanced Platform Technology Center, Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH 44106, USA.
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              Text: 2026 Jul 27
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