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Identification of Pyrazolidine-3-One Derivatives as a Novel Structural Scaffold for ATP Synthase Inhibitors.

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Title: Identification of Pyrazolidine-3-One Derivatives as a Novel Structural Scaffold for ATP Synthase Inhibitors.
Authors: Reichert L; Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zürich, Zurich, Switzerland., Delparente A; Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zürich, Zurich, Switzerland., Hipfinger IR; Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zürich, Zurich, Switzerland., Reininger L; Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zürich, Zurich, Switzerland., Castro AP; Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zürich, Zurich, Switzerland., Hubin DJ; Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zürich, Zurich, Switzerland., Schibli R; Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zürich, Zurich, Switzerland., Fraley AE; Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zürich, Zurich, Switzerland., Mu L; Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zürich, Zurich, Switzerland.
Source: ChemMedChem [ChemMedChem] 2026 Jul 29; Vol. 21 (14), pp. e70399.
Publication Type: Journal Article
Journal Info: Publisher: Wiley-VCH Country of Publication: Germany NLM ID: 101259013 Publication Model: Print Cited Medium: Internet ISSN: 1860-7187 (Electronic) Linking ISSN: 18607179 NLM ISO Abbreviation: ChemMedChem Subsets: MEDLINE
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  Data: Identification of Pyrazolidine-3-One Derivatives as a Novel Structural Scaffold for ATP Synthase Inhibitors.
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  Data: <searchLink fieldCode="AU" term="%22Reichert+L%22">Reichert L</searchLink>; Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zürich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Delparente+A%22">Delparente A</searchLink>; Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zürich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Hipfinger+IR%22">Hipfinger IR</searchLink>; Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zürich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Reininger+L%22">Reininger L</searchLink>; Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zürich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Castro+AP%22">Castro AP</searchLink>; Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zürich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Hubin+DJ%22">Hubin DJ</searchLink>; Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zürich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Schibli+R%22">Schibli R</searchLink>; Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zürich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Fraley+AE%22">Fraley AE</searchLink>; Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zürich, Zurich, Switzerland.<br /><searchLink fieldCode="AU" term="%22Mu+L%22">Mu L</searchLink>; Department of Chemistry and Applied Biosciences, Institute of Pharmaceutical Sciences, ETH Zürich, Zurich, Switzerland.
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              Text: 2026 Jul 29
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