Therapeutic Effects of Combined 6-Shogaol and Ibudilast on Neuroinflammation and Behavioral Deficits in a Cuprizone Mouse Model of Multiple Sclerosis.
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| Title: | Therapeutic Effects of Combined 6-Shogaol and Ibudilast on Neuroinflammation and Behavioral Deficits in a Cuprizone Mouse Model of Multiple Sclerosis. |
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| Authors: | Alshahrany GA; Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia., Alyami KA; Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia., Alzahrani NA; Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia., Alam MZ; Neuroscience and Geroscience Research Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia.; Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia., Alghamdi BS; Neuroscience and Geroscience Research Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia.; Department of Physiology, Faculty of Medicine, King Abdulaziz University, Jeddah 21589, Saudi Arabia., Omar UM; Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia.; Princess Dr. Najla Bint Saud Al-Saud Center for Excellence Research in Biotechnology, King Abdulaziz University, Jeddah 21589, Saudi Arabia., Banjabi AA; Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia., Alshaibi HF; Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia.; Stem Cell Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia., Jambi RJ; The Applied College, Department of Health Information Technology, King Abdulaziz University, Jeddah 21589, Saudi Arabia., Al-Otaibi KM; Department of Chemistry, Faculty of Science, Al-Baha University, Al-Baha 65799, Saudi Arabia., Alsufiani HM; Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia.; Experimental Biochemistry Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia. |
| Source: | Pharmaceuticals (Basel, Switzerland) [Pharmaceuticals (Basel)] 2026 Jun 28; Vol. 19 (7). Date of Electronic Publication: 2026 Jun 28. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: MDPI Country of Publication: Switzerland NLM ID: 101238453 Publication Model: Electronic Cited Medium: Print ISSN: 1424-8247 (Print) Linking ISSN: 14248247 NLM ISO Abbreviation: Pharmaceuticals (Basel) Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42515688 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Therapeutic Effects of Combined 6-Shogaol and Ibudilast on Neuroinflammation and Behavioral Deficits in a Cuprizone Mouse Model of Multiple Sclerosis. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Alshahrany+GA%22">Alshahrany GA</searchLink>; Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Alyami+KA%22">Alyami KA</searchLink>; Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Alzahrani+NA%22">Alzahrani NA</searchLink>; Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Alam+MZ%22">Alam MZ</searchLink>; Neuroscience and Geroscience Research Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia.; Department of Medical Laboratory Sciences, Faculty of Applied Medical Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Alghamdi+BS%22">Alghamdi BS</searchLink>; Neuroscience and Geroscience Research Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia.; Department of Physiology, Faculty of Medicine, King Abdulaziz University, Jeddah 21589, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Omar+UM%22">Omar UM</searchLink>; Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia.; Princess Dr. Najla Bint Saud Al-Saud Center for Excellence Research in Biotechnology, King Abdulaziz University, Jeddah 21589, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Banjabi+AA%22">Banjabi AA</searchLink>; Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Alshaibi+HF%22">Alshaibi HF</searchLink>; Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia.; Stem Cell Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Jambi+RJ%22">Jambi RJ</searchLink>; The Applied College, Department of Health Information Technology, King Abdulaziz University, Jeddah 21589, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Al-Otaibi+KM%22">Al-Otaibi KM</searchLink>; Department of Chemistry, Faculty of Science, Al-Baha University, Al-Baha 65799, Saudi Arabia.<br /><searchLink fieldCode="AU" term="%22Alsufiani+HM%22">Alsufiani HM</searchLink>; Department of Biochemistry, Faculty of Sciences, King Abdulaziz University, Jeddah 21589, Saudi Arabia.; Experimental Biochemistry Unit, King Fahd Medical Research Center, King Abdulaziz University, Jeddah 21589, Saudi Arabia. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101238453%22">Pharmaceuticals (Basel, Switzerland)</searchLink> [Pharmaceuticals (Basel)] 2026 Jun 28; Vol. 19 (7). <i>Date of Electronic Publication: </i>2026 Jun 28. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22MDPI%22">MDPI </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>101238453 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>1424-8247 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214248247%22">14248247 </searchLink><i>NLM ISO Abbreviation: </i>Pharmaceuticals (Basel) <i>Subsets: </i>PubMed not MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42515688 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.3390/ph19071004 Languages: – Code: eng Text: English Titles: – TitleFull: Therapeutic Effects of Combined 6-Shogaol and Ibudilast on Neuroinflammation and Behavioral Deficits in a Cuprizone Mouse Model of Multiple Sclerosis. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Alshahrany GA – PersonEntity: Name: NameFull: Alyami KA – PersonEntity: Name: NameFull: Alzahrani NA – PersonEntity: Name: NameFull: Alam MZ – PersonEntity: Name: NameFull: Alghamdi BS – PersonEntity: Name: NameFull: Omar UM – PersonEntity: Name: NameFull: Banjabi AA – PersonEntity: Name: NameFull: Alshaibi HF – PersonEntity: Name: NameFull: Jambi RJ – PersonEntity: Name: NameFull: Al-Otaibi KM – PersonEntity: Name: NameFull: Alsufiani HM IsPartOfRelationships: – BibEntity: Dates: – D: 28 M: 06 Text: 2026 Jun 28 Type: published Y: 2026 Identifiers: – Type: issn-print Value: 1424-8247 Numbering: – Type: volume Value: 19 – Type: issue Value: 7 Titles: – TitleFull: Pharmaceuticals (Basel, Switzerland) Type: main |
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