Tailored FcγR blockade enhances immune checkpoint therapy and overcomes resistance.

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Title: Tailored FcγR blockade enhances immune checkpoint therapy and overcomes resistance.
Authors: Oldham RJ; Antibody and Vaccine Group, School of Cancer Sciences, University of Southampton, Southampton, UK., Mårtensson L; BioInvent, Lund, Sweden., Semmrich M; BioInvent, Lund, Sweden., Yoosuf N; BioInvent, Lund, Sweden., Holmkvist P; BioInvent, Lund, Sweden., Graham LV; Antibody and Vaccine Group, School of Cancer Sciences, University of Southampton, Southampton, UK., Taylor MC; Antibody and Vaccine Group, School of Cancer Sciences, University of Southampton, Southampton, UK., Cleary KLS; Antibody and Vaccine Group, School of Cancer Sciences, University of Southampton, Southampton, UK., Yazdani M; Antibody and Vaccine Group, School of Cancer Sciences, University of Southampton, Southampton, UK., Buckingham JF; Antibody and Vaccine Group, School of Cancer Sciences, University of Southampton, Southampton, UK., Roghanian A; Antibody and Vaccine Group, School of Cancer Sciences, University of Southampton, Southampton, UK., Karlsson I; BioInvent, Lund, Sweden., Beers SA; Antibody and Vaccine Group, School of Cancer Sciences, University of Southampton, Southampton, UK., Teige I; BioInvent, Lund, Sweden., Cragg MS; Antibody and Vaccine Group, School of Cancer Sciences, University of Southampton, Southampton, UK., Frendéus B; Antibody and Vaccine Group, School of Cancer Sciences, University of Southampton, Southampton, UK. bjorn.frendeus@bioinvent.com.; BioInvent, Lund, Sweden. bjorn.frendeus@bioinvent.com.
Source: Journal of experimental & clinical cancer research : CR [J Exp Clin Cancer Res] 2026 Jul 25; Vol. 45 (1). Date of Electronic Publication: 2026 Jul 25.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 8308647 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-9966 (Electronic) Linking ISSN: 03929078 NLM ISO Abbreviation: J Exp Clin Cancer Res Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Oldham+RJ%22">Oldham RJ</searchLink>; Antibody and Vaccine Group, School of Cancer Sciences, University of Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Mårtensson+L%22">Mårtensson L</searchLink>; BioInvent, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Semmrich+M%22">Semmrich M</searchLink>; BioInvent, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Yoosuf+N%22">Yoosuf N</searchLink>; BioInvent, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Holmkvist+P%22">Holmkvist P</searchLink>; BioInvent, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Graham+LV%22">Graham LV</searchLink>; Antibody and Vaccine Group, School of Cancer Sciences, University of Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Taylor+MC%22">Taylor MC</searchLink>; Antibody and Vaccine Group, School of Cancer Sciences, University of Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Cleary+KLS%22">Cleary KLS</searchLink>; Antibody and Vaccine Group, School of Cancer Sciences, University of Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Yazdani+M%22">Yazdani M</searchLink>; Antibody and Vaccine Group, School of Cancer Sciences, University of Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Buckingham+JF%22">Buckingham JF</searchLink>; Antibody and Vaccine Group, School of Cancer Sciences, University of Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Roghanian+A%22">Roghanian A</searchLink>; Antibody and Vaccine Group, School of Cancer Sciences, University of Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Karlsson+I%22">Karlsson I</searchLink>; BioInvent, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Beers+SA%22">Beers SA</searchLink>; Antibody and Vaccine Group, School of Cancer Sciences, University of Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Teige+I%22">Teige I</searchLink>; BioInvent, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Cragg+MS%22">Cragg MS</searchLink>; Antibody and Vaccine Group, School of Cancer Sciences, University of Southampton, Southampton, UK.<br /><searchLink fieldCode="AU" term="%22Frendéus+B%22">Frendéus B</searchLink>; Antibody and Vaccine Group, School of Cancer Sciences, University of Southampton, Southampton, UK. bjorn.frendeus@bioinvent.com.; BioInvent, Lund, Sweden. bjorn.frendeus@bioinvent.com.
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  Data: <searchLink fieldCode="JN" term="%228308647%22">Journal of experimental & clinical cancer research : CR</searchLink> [J Exp Clin Cancer Res] 2026 Jul 25; Vol. 45 (1). <i>Date of Electronic Publication: </i>2026 Jul 25.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>8308647 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1756-9966 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2203929078%22">03929078 </searchLink><i>NLM ISO Abbreviation: </i>J Exp Clin Cancer Res <i>Subsets: </i>MEDLINE
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        Value: 10.1186/s13046-026-03785-5
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              Text: 2026 Jul 25
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