Novel mutations in ZMYND15 expand the phenotypic spectrum to acephalic spermatozoa: abnormal sperm head-tail connection mediated by SUN5.

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Title: Novel mutations in ZMYND15 expand the phenotypic spectrum to acephalic spermatozoa: abnormal sperm head-tail connection mediated by SUN5.
Authors: Zhang QJ; Institute of Reproductive and Stem Cell Engineering, School of Basic Medical Science, NHC Key Laboratory of Human Stem Cell and Reproductive Engineering, Central South University, Changsha 410013, China.; Clinical Research Center for Reproduction and Genetics in Hunan Province, Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha 410008, China.; Clinical Laboratory, Hunan Guangxiu Hospital, Hunan Normal University, Changsha 410013, China., Lin H; Clinical Laboratory, Hunan Guangxiu Hospital, Hunan Normal University, Changsha 410013, China., Hao RL; Clinical Laboratory, Hunan Guangxiu Hospital, Hunan Normal University, Changsha 410013, China., Zhang YF; Department of Laboratory Medicine, The Third Xiangya Hospital, Central South University, Changsha 410013, China., Lin YP; Clinical Laboratory, Hunan Guangxiu Hospital, Hunan Normal University, Changsha 410013, China., Zeng SC; Clinical Laboratory, Hunan Guangxiu Hospital, Hunan Normal University, Changsha 410013, China.; Scientific Research Department, Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha 410008, China., Zhang H; Institute of Reproductive and Stem Cell Engineering, School of Basic Medical Science, NHC Key Laboratory of Human Stem Cell and Reproductive Engineering, Central South University, Changsha 410013, China.; Clinical Research Center for Reproduction and Genetics in Hunan Province, Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha 410008, China., Li WN; Institute of Reproductive and Stem Cell Engineering, School of Basic Medical Science, NHC Key Laboratory of Human Stem Cell and Reproductive Engineering, Central South University, Changsha 410013, China.; Clinical Research Center for Reproduction and Genetics in Hunan Province, Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha 410008, China.; Department of Urology (Andrology), Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha 410008, China.
Source: Asian journal of andrology [Asian J Androl] 2026 Jul 28. Date of Electronic Publication: 2026 Jul 28.
Publication Type: Journal Article
Journal Info: Publisher: Shanghai Materia Medica Country of Publication: China NLM ID: 100942132 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1745-7262 (Electronic) Linking ISSN: 1008682X NLM ISO Abbreviation: Asian J Androl Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Novel mutations in ZMYND15 expand the phenotypic spectrum to acephalic spermatozoa: abnormal sperm head-tail connection mediated by SUN5.
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  Data: <searchLink fieldCode="AU" term="%22Zhang+QJ%22">Zhang QJ</searchLink>; Institute of Reproductive and Stem Cell Engineering, School of Basic Medical Science, NHC Key Laboratory of Human Stem Cell and Reproductive Engineering, Central South University, Changsha 410013, China.; Clinical Research Center for Reproduction and Genetics in Hunan Province, Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha 410008, China.; Clinical Laboratory, Hunan Guangxiu Hospital, Hunan Normal University, Changsha 410013, China.<br /><searchLink fieldCode="AU" term="%22Lin+H%22">Lin H</searchLink>; Clinical Laboratory, Hunan Guangxiu Hospital, Hunan Normal University, Changsha 410013, China.<br /><searchLink fieldCode="AU" term="%22Hao+RL%22">Hao RL</searchLink>; Clinical Laboratory, Hunan Guangxiu Hospital, Hunan Normal University, Changsha 410013, China.<br /><searchLink fieldCode="AU" term="%22Zhang+YF%22">Zhang YF</searchLink>; Department of Laboratory Medicine, The Third Xiangya Hospital, Central South University, Changsha 410013, China.<br /><searchLink fieldCode="AU" term="%22Lin+YP%22">Lin YP</searchLink>; Clinical Laboratory, Hunan Guangxiu Hospital, Hunan Normal University, Changsha 410013, China.<br /><searchLink fieldCode="AU" term="%22Zeng+SC%22">Zeng SC</searchLink>; Clinical Laboratory, Hunan Guangxiu Hospital, Hunan Normal University, Changsha 410013, China.; Scientific Research Department, Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha 410008, China.<br /><searchLink fieldCode="AU" term="%22Zhang+H%22">Zhang H</searchLink>; Institute of Reproductive and Stem Cell Engineering, School of Basic Medical Science, NHC Key Laboratory of Human Stem Cell and Reproductive Engineering, Central South University, Changsha 410013, China.; Clinical Research Center for Reproduction and Genetics in Hunan Province, Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha 410008, China.<br /><searchLink fieldCode="AU" term="%22Li+WN%22">Li WN</searchLink>; Institute of Reproductive and Stem Cell Engineering, School of Basic Medical Science, NHC Key Laboratory of Human Stem Cell and Reproductive Engineering, Central South University, Changsha 410013, China.; Clinical Research Center for Reproduction and Genetics in Hunan Province, Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha 410008, China.; Department of Urology (Andrology), Reproductive and Genetic Hospital of CITIC-Xiangya, Changsha 410008, China.
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  Data: <searchLink fieldCode="JN" term="%22100942132%22">Asian journal of andrology</searchLink> [Asian J Androl] 2026 Jul 28. <i>Date of Electronic Publication: </i>2026 Jul 28.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Shanghai+Materia+Medica%22">Shanghai Materia Medica </searchLink><i>Country of Publication: </i>China <i>NLM ID: </i>100942132 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1745-7262 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%221008682X%22">1008682X </searchLink><i>NLM ISO Abbreviation: </i>Asian J Androl <i>Subsets: </i>MEDLINE
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RecordInfo BibRecord:
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      – Type: doi
        Value: 10.4103/aja2025109
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      – Code: eng
        Text: English
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      – TitleFull: Novel mutations in ZMYND15 expand the phenotypic spectrum to acephalic spermatozoa: abnormal sperm head-tail connection mediated by SUN5.
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            – D: 28
              M: 07
              Text: 2026 Jul 28
              Type: published
              Y: 2026
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