Timing, Translation, and Preparedness: Lessons Learned From COVID-19 Anticoagulation in Noncritically Ill Hospitalized Patients.

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Title: Timing, Translation, and Preparedness: Lessons Learned From COVID-19 Anticoagulation in Noncritically Ill Hospitalized Patients.
Authors: Tritschler T; Department of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland; Inflammation and Chronic Disease Program, University of Ottawa, Ottawa, Ontario, Canada. Electronic address: tobias.tritschler@insel.ch., Fuster V; Icahn School of Medicine at Mount Sinai, Mount Sinai Fuster Heart Hospital, New York, New York, USA; Centro Nacional de Investigaciones Cardiovasculares, Madrid, Spain., Lawler PR; Cardiology and Critical Care Medicine, University Health Network and University of Toronto, Toronto, Ontario, Canada; Cardiology and Critical Care, McGill University Health Centre, and McGill University, Montreal, Quebec, Canada., Farkouh ME; Peter Munk Cardiac Centre, University of Toronto, Toronto, Ontario, Canada; Smidt Heart Institute, Cedars-Sinai Health System, Los Angeles, California, USA., Marx CE; Department of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Neal MD; Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA., Sholzberg M; Departments of Medicine, and Laboratory Medicine and Pathobiology, Li Ka Shing Knowledge Institute, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada., Spyropoulos AC; Northwell Health at Lenox Hill Hospital Department of Medicine, New York, New York, USA; The Feinstein Institutes for Medical Research, New York, New York, USA., Tong SYC; Victorian Infectious Diseases Service, The Royal Melbourne Hospital, at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia; Department of Infectious Diseases, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia; Melbourne Centre for Clinical Trials, School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia., Muñoz-Rivas N; Department of Internal Medicine, Infanta Leonor University Hospital, Complutense University of Madrid, Madrid, Spain., Blondon M; Faculty of Medicine and Geneva University Hospitals, Division of Angiology and Haemostasis, Geneva, Switzerland., Berger JS; Department of Medicine, New York University Grossman School of Medicine, New York, New York, USA., Bikdeli B; Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA; Yale-New Haven Hospital/Yale Center for Outcomes Research and Evaluation (CORE), New Haven, Connecticut, USA., Cattaneo M; Fondazione Arianna Anticoagulazione, Bologna, Italy., Cushman M; Department of Medicine, Larner College of Medicine, University of Vermont, Burlington, Vermont, USA., Goldin M; Northwell Health at Lenox Hill Hospital Department of Medicine, New York, New York, USA; The Feinstein Institutes for Medical Research, New York, New York, USA., Goligher EC; Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada., Hochman JS; Department of Medicine, New York University Grossman School of Medicine, New York, New York, USA., Jüni P; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom., McQuilten ZK; Monash University, Melbourne, Victoria, Australia; Monash Health, Melbourne, Victoria, Australia., Morici N; IRCCS Fondazione Don Gnocchi, ETS, Milan, Italy., Sadeghipour P; Vascular Disease and Thrombosis Research Center, Rajaie Cardiovascular Institute, Tehran, Iran., Venkatesh B; University of Queensland, Brisbane, Queensland, Australia; The George Institute for Global Health, Sydney, New South Wales, Australia; The George Institute for Global Health, Delhi, India; Gold Coast University Hospital, Southport, Queensland, Australia; University of New South Wales, Sydney, New South Wales, Australia., Zuily S; Department of Vascular Medicine, University Hospital of Nancy, Nancy, France., Amstutz A; CLEAR Methods Center, Division Clinical Epidemiology, Department of Clinical Research, University Hospital Basel and University of Basel, Basel, Switzerland; Oslo Center for Biostatistics and Epidemiology, Oslo University Hospital, Oslo, Norway; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom., Aujesky D; Department of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Carrier M; Inflammation and Chronic Disease Program, University of Ottawa, Ottawa, Ontario, Canada; Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada., Hofstetter RV; Department of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland., Murthy S; Department of Pediatrics, University of British Columbia, Vancouver, British Columbia, Canada., Rodger M; Department of Medicine, McGill University, McGill University Health Center, Montreal, Quebec, Canada., Skeith L; Division of Hematology and Hematological Malignancies, University of Calgary, Calgary, Alberta, Canada., Veroniki AA; Center for Evidence Synthesis in Health, Department of Health Services, Policy, and Practice, Brown University School of Public Health, Providence, Rhode Island, USA; Knowledge Translation Program, Li Ka Shing Knowledge Institute, St Michael's Hospital, Toronto, Ontario, Canada; Institute for Health Policy, Management, and Evaluation, University of Toronto, Toronto, Ontario, Canada., Hutton B; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom; Methodological and Implementation Research, The Ottawa Hospital Research Institute, Ottawa, Ontario, Canada., Zarychanski R; Department of Internal Medicine, Rady Faculty of Health Sciences, University of Manitoba, Winnipeg, Manitoba, Canada., Stone GW; Icahn School of Medicine at Mount Sinai, Mount Sinai Fuster Heart Hospital, New York, New York, USA., Le Gal G; Inflammation and Chronic Disease Program, University of Ottawa, Ottawa, Ontario, Canada; Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada.
Corporate Authors: Anticoagulation in COVID-19 Investigators
Source: Journal of the American College of Cardiology [J Am Coll Cardiol] 2026 Jul 28; Vol. 88 (4), pp. 437-450.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Biomedical Country of Publication: United States NLM ID: 8301365 Publication Model: Print Cited Medium: Internet ISSN: 1558-3597 (Electronic) Linking ISSN: 07351097 NLM ISO Abbreviation: J Am Coll Cardiol Subsets: MEDLINE
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Department of Surgery, University of Pittsburgh, Pittsburgh, Pennsylvania, USA.<br /><searchLink fieldCode="AU" term="%22Sholzberg+M%22">Sholzberg M</searchLink>; Departments of Medicine, and Laboratory Medicine and Pathobiology, Li Ka Shing Knowledge Institute, St Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Spyropoulos+AC%22">Spyropoulos AC</searchLink>; Northwell Health at Lenox Hill Hospital Department of Medicine, New York, New York, USA; The Feinstein Institutes for Medical Research, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Tong+SYC%22">Tong SYC</searchLink>; Victorian Infectious Diseases Service, The Royal Melbourne Hospital, at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia; Department of Infectious Diseases, The University of Melbourne at the Peter Doherty Institute for Infection and Immunity, Melbourne, Victoria, Australia; Melbourne Centre for Clinical Trials, School of Population and Global Health, University of Melbourne, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Muñoz-Rivas+N%22">Muñoz-Rivas N</searchLink>; Department of Internal Medicine, Infanta Leonor University Hospital, Complutense University of Madrid, Madrid, Spain.<br /><searchLink fieldCode="AU" term="%22Blondon+M%22">Blondon M</searchLink>; Faculty of Medicine and Geneva University Hospitals, Division of Angiology and Haemostasis, Geneva, Switzerland.<br /><searchLink fieldCode="AU" term="%22Berger+JS%22">Berger JS</searchLink>; Department of Medicine, New York University Grossman School of Medicine, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Bikdeli+B%22">Bikdeli B</searchLink>; Division of Cardiovascular Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts, USA; Yale-New Haven Hospital/Yale Center for Outcomes Research and Evaluation (CORE), New Haven, Connecticut, USA.<br /><searchLink fieldCode="AU" term="%22Cattaneo+M%22">Cattaneo M</searchLink>; Fondazione Arianna Anticoagulazione, Bologna, Italy.<br /><searchLink fieldCode="AU" term="%22Cushman+M%22">Cushman M</searchLink>; Department of Medicine, Larner College of Medicine, University of Vermont, Burlington, Vermont, USA.<br /><searchLink fieldCode="AU" term="%22Goldin+M%22">Goldin M</searchLink>; Northwell Health at Lenox Hill Hospital Department of Medicine, New York, New York, USA; The Feinstein Institutes for Medical Research, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Goligher+EC%22">Goligher EC</searchLink>; Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Hochman+JS%22">Hochman JS</searchLink>; Department of Medicine, New York University Grossman School of Medicine, New York, New York, USA.<br /><searchLink fieldCode="AU" term="%22Jüni+P%22">Jüni P</searchLink>; Clinical Trial Service Unit and Epidemiological Studies Unit, Nuffield Department of Population Health, University of Oxford, Oxford, United Kingdom.<br /><searchLink fieldCode="AU" term="%22McQuilten+ZK%22">McQuilten ZK</searchLink>; Monash University, Melbourne, Victoria, Australia; Monash Health, Melbourne, Victoria, Australia.<br /><searchLink fieldCode="AU" term="%22Morici+N%22">Morici N</searchLink>; IRCCS Fondazione Don Gnocchi, ETS, Milan, Italy.<br /><searchLink fieldCode="AU" term="%22Sadeghipour+P%22">Sadeghipour P</searchLink>; Vascular Disease and Thrombosis Research Center, Rajaie Cardiovascular Institute, Tehran, Iran.<br /><searchLink fieldCode="AU" term="%22Venkatesh+B%22">Venkatesh B</searchLink>; University of Queensland, Brisbane, Queensland, Australia; The George Institute for Global Health, Sydney, New South Wales, Australia; The George Institute for Global Health, Delhi, India; Gold Coast University Hospital, Southport, Queensland, Australia; University of New South Wales, Sydney, New South Wales, Australia.<br /><searchLink fieldCode="AU" term="%22Zuily+S%22">Zuily S</searchLink>; Department of Vascular Medicine, University Hospital of Nancy, Nancy, France.<br /><searchLink fieldCode="AU" term="%22Amstutz+A%22">Amstutz A</searchLink>; CLEAR Methods Center, Division Clinical Epidemiology, Department of Clinical Research, University Hospital Basel and University of Basel, Basel, Switzerland; Oslo Center for Biostatistics and Epidemiology, Oslo University Hospital, Oslo, Norway; Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Aujesky+D%22">Aujesky D</searchLink>; Department of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Carrier+M%22">Carrier M</searchLink>; Inflammation and Chronic Disease Program, University of Ottawa, Ottawa, Ontario, Canada; Department of Medicine, University of Ottawa, Ottawa, Ontario, Canada.<br /><searchLink fieldCode="AU" term="%22Hofstetter+RV%22">Hofstetter RV</searchLink>; Department of General Internal Medicine, Inselspital, Bern University Hospital, University of Bern, Bern, Switzerland.<br /><searchLink fieldCode="AU" term="%22Murthy+S%22">Murthy S</searchLink>; 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