Phase 3 Trial of Weekly Oral Islatravir-Lenacapavir for HIV-1 Treatment.

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Title: Phase 3 Trial of Weekly Oral Islatravir-Lenacapavir for HIV-1 Treatment.
Authors: Rockstroh JK; Department of Medicine I, University Hospital Bonn, Bonn, Germany., Ramgopal MN; Midway Immunology and Research Center, Fort Pierce, FL., Curran Fàbregas A; Department of Infectious Diseases, Vall d'Hebron University Hospital, Barcelona., Hedgcock M; Spectrum Health, Vancouver, BC, Canada., Workowski KA; Department of Medicine, Emory University, Atlanta., Ronot-Bregigeon S; Hôpital Sainte-Marguerite, Aix-Marseille Université, Assistance Publique-Hôpitaux de Marseille, Marseille, France., Cassetti I; Helios Salud, Buenos Aires., Brinson C; Central Texas Clinical Research, Austin., Gupta SK; Indiana University School of Medicine, Indianapolis., Hung CC; Department of Internal Medicine, National Taiwan University Hospital Yunlin Branch, Yunlin., O'Reilly M; East Sydney Doctors, Darlinghurst, NSW, Australia.; Taylor Square Private Clinic, Surry Hills, NSW, Australia., Slim J; New York Medical College, Valhalla., Gatanaga H; Japan Institute for Health Security, National Center for Global Health and Medicine, Tokyo., Shalit P; Peter Shalit MD and Associates, Seattle., Liu SY; Gilead Sciences, Foster City, CA., Klopfer SO; Merck, Rahway, NJ., Shihadeh F; Gilead Sciences, Foster City, CA., Patel N; Merck, Rahway, NJ., Mercier RC; Gilead Sciences, Foster City, CA., Shaughnessy M; Merck, Rahway, NJ., Dvory-Sobol H; Gilead Sciences, Foster City, CA., SenGupta D; Gilead Sciences, Foster City, CA., Llamoso C; Merck, Rahway, NJ., Rhee MS; Gilead Sciences, Foster City, CA., Orkin C; SHARE Collaborative, Blizard Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London.
Corporate Authors: ISLEND-1 Study Team
Source: The New England journal of medicine [N Engl J Med] 2026 Jul 29. Date of Electronic Publication: 2026 Jul 29.
Publication Type: Journal Article
Journal Info: Publisher: Massachusetts Medical Society Country of Publication: United States NLM ID: 0255562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1533-4406 (Electronic) Linking ISSN: 00284793 NLM ISO Abbreviation: N Engl J Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Rockstroh+JK%22">Rockstroh JK</searchLink>; Department of Medicine I, University Hospital Bonn, Bonn, Germany.<br /><searchLink fieldCode="AU" term="%22Ramgopal+MN%22">Ramgopal MN</searchLink>; Midway Immunology and Research Center, Fort Pierce, FL.<br /><searchLink fieldCode="AU" term="%22Curran+Fàbregas+A%22">Curran Fàbregas A</searchLink>; Department of Infectious Diseases, Vall d'Hebron University Hospital, Barcelona.<br /><searchLink fieldCode="AU" term="%22Hedgcock+M%22">Hedgcock M</searchLink>; Spectrum Health, Vancouver, BC, Canada.<br /><searchLink fieldCode="AU" term="%22Workowski+KA%22">Workowski KA</searchLink>; Department of Medicine, Emory University, Atlanta.<br /><searchLink fieldCode="AU" term="%22Ronot-Bregigeon+S%22">Ronot-Bregigeon S</searchLink>; Hôpital Sainte-Marguerite, Aix-Marseille Université, Assistance Publique-Hôpitaux de Marseille, Marseille, France.<br /><searchLink fieldCode="AU" term="%22Cassetti+I%22">Cassetti I</searchLink>; Helios Salud, Buenos Aires.<br /><searchLink fieldCode="AU" term="%22Brinson+C%22">Brinson C</searchLink>; Central Texas Clinical Research, Austin.<br /><searchLink fieldCode="AU" term="%22Gupta+SK%22">Gupta SK</searchLink>; Indiana University School of Medicine, Indianapolis.<br /><searchLink fieldCode="AU" term="%22Hung+CC%22">Hung CC</searchLink>; Department of Internal Medicine, National Taiwan University Hospital Yunlin Branch, Yunlin.<br /><searchLink fieldCode="AU" term="%22O'Reilly+M%22">O'Reilly M</searchLink>; East Sydney Doctors, Darlinghurst, NSW, Australia.; Taylor Square Private Clinic, Surry Hills, NSW, Australia.<br /><searchLink fieldCode="AU" term="%22Slim+J%22">Slim J</searchLink>; New York Medical College, Valhalla.<br /><searchLink fieldCode="AU" term="%22Gatanaga+H%22">Gatanaga H</searchLink>; Japan Institute for Health Security, National Center for Global Health and Medicine, Tokyo.<br /><searchLink fieldCode="AU" term="%22Shalit+P%22">Shalit P</searchLink>; Peter Shalit MD and Associates, Seattle.<br /><searchLink fieldCode="AU" term="%22Liu+SY%22">Liu SY</searchLink>; Gilead Sciences, Foster City, CA.<br /><searchLink fieldCode="AU" term="%22Klopfer+SO%22">Klopfer SO</searchLink>; Merck, Rahway, NJ.<br /><searchLink fieldCode="AU" term="%22Shihadeh+F%22">Shihadeh F</searchLink>; Gilead Sciences, Foster City, CA.<br /><searchLink fieldCode="AU" term="%22Patel+N%22">Patel N</searchLink>; Merck, Rahway, NJ.<br /><searchLink fieldCode="AU" term="%22Mercier+RC%22">Mercier RC</searchLink>; Gilead Sciences, Foster City, CA.<br /><searchLink fieldCode="AU" term="%22Shaughnessy+M%22">Shaughnessy M</searchLink>; Merck, Rahway, NJ.<br /><searchLink fieldCode="AU" term="%22Dvory-Sobol+H%22">Dvory-Sobol H</searchLink>; Gilead Sciences, Foster City, CA.<br /><searchLink fieldCode="AU" term="%22SenGupta+D%22">SenGupta D</searchLink>; Gilead Sciences, Foster City, CA.<br /><searchLink fieldCode="AU" term="%22Llamoso+C%22">Llamoso C</searchLink>; Merck, Rahway, NJ.<br /><searchLink fieldCode="AU" term="%22Rhee+MS%22">Rhee MS</searchLink>; Gilead Sciences, Foster City, CA.<br /><searchLink fieldCode="AU" term="%22Orkin+C%22">Orkin C</searchLink>; SHARE Collaborative, Blizard Institute, Faculty of Medicine and Dentistry, Queen Mary University of London, London.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Massachusetts+Medical+Society%22">Massachusetts Medical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0255562 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1533-4406 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200284793%22">00284793 </searchLink><i>NLM ISO Abbreviation: </i>N Engl J Med <i>Subsets: </i>MEDLINE
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