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A xeno-free human iPSC-derived prostate organoid platform for multilineage differentiation and genetic manipulation.

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Title: A xeno-free human iPSC-derived prostate organoid platform for multilineage differentiation and genetic manipulation.
Authors: Shaikh N; Newcastle University, Newcastle, UK., Teasdale M; Newcastle University, Newcastle, UK., Walker LJ; Newcastle University, Newcastle, UK., Wilson L; Newcastle University, Newcastle, UK., Howarth R; Newcastle University, Newcastle, UK., Saleem S; Newcastle University, Newcastle, UK., Logsdon J; Newcastle University, Newcastle, UK., Hepburn AC; Newcastle University, Newcastle, UK., Nelson R; Newcastle University, Newcastle, UK., Lian Q; University of Cambridge, Cambridge, UK., Elizondo AC; Newcastle University, Newcastle, UK., Hussain R; Newcastle University, Newcastle, UK., Coxhead J; Newcastle University, Newcastle, UK., Gaughan L; Newcastle University, Newcastle, UK., Lako M; Newcastle University, Newcastle, UK., Scott E; Newcastle University, Newcastle, UK., Robson CN; Newcastle University, Newcastle, UK., Simons B; University of Cambridge, Cambridge, UK., Hayward SW; Endeavor Health Research Institute, Evanston, IL, USA; Pritzker School of Medicine, University of Chicago, Chicago, IL, USA., Strand DW; UT Southwestern Medical Center, Dallas, TX, USA., Heer R; Newcastle University, Newcastle, UK; Imperial College London, London, UK., Buskin A; Newcastle University, Newcastle, UK. Electronic address: adriana.buskin@ncl.ac.uk.
Source: Cell reports methods [Cell Rep Methods] 2026 Jul 29, pp. 101538. Date of Electronic Publication: 2026 Jul 29.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier Inc Country of Publication: United States NLM ID: 9918227360606676 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2667-2375 (Electronic) Linking ISSN: 26672375 NLM ISO Abbreviation: Cell Rep Methods Subsets: MEDLINE
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  Data: A xeno-free human iPSC-derived prostate organoid platform for multilineage differentiation and genetic manipulation.
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  Data: <searchLink fieldCode="AU" term="%22Shaikh+N%22">Shaikh N</searchLink>; Newcastle University, Newcastle, UK.<br /><searchLink fieldCode="AU" term="%22Teasdale+M%22">Teasdale M</searchLink>; Newcastle University, Newcastle, UK.<br /><searchLink fieldCode="AU" term="%22Walker+LJ%22">Walker LJ</searchLink>; Newcastle University, Newcastle, UK.<br /><searchLink fieldCode="AU" term="%22Wilson+L%22">Wilson L</searchLink>; Newcastle University, Newcastle, UK.<br /><searchLink fieldCode="AU" term="%22Howarth+R%22">Howarth R</searchLink>; Newcastle University, Newcastle, UK.<br /><searchLink fieldCode="AU" term="%22Saleem+S%22">Saleem S</searchLink>; Newcastle University, Newcastle, UK.<br /><searchLink fieldCode="AU" term="%22Logsdon+J%22">Logsdon J</searchLink>; Newcastle University, Newcastle, UK.<br /><searchLink fieldCode="AU" term="%22Hepburn+AC%22">Hepburn AC</searchLink>; Newcastle University, Newcastle, UK.<br /><searchLink fieldCode="AU" term="%22Nelson+R%22">Nelson R</searchLink>; Newcastle University, Newcastle, UK.<br /><searchLink fieldCode="AU" term="%22Lian+Q%22">Lian Q</searchLink>; University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Elizondo+AC%22">Elizondo AC</searchLink>; Newcastle University, Newcastle, UK.<br /><searchLink fieldCode="AU" term="%22Hussain+R%22">Hussain R</searchLink>; Newcastle University, Newcastle, UK.<br /><searchLink fieldCode="AU" term="%22Coxhead+J%22">Coxhead J</searchLink>; Newcastle University, Newcastle, UK.<br /><searchLink fieldCode="AU" term="%22Gaughan+L%22">Gaughan L</searchLink>; Newcastle University, Newcastle, UK.<br /><searchLink fieldCode="AU" term="%22Lako+M%22">Lako M</searchLink>; Newcastle University, Newcastle, UK.<br /><searchLink fieldCode="AU" term="%22Scott+E%22">Scott E</searchLink>; Newcastle University, Newcastle, UK.<br /><searchLink fieldCode="AU" term="%22Robson+CN%22">Robson CN</searchLink>; Newcastle University, Newcastle, UK.<br /><searchLink fieldCode="AU" term="%22Simons+B%22">Simons B</searchLink>; University of Cambridge, Cambridge, UK.<br /><searchLink fieldCode="AU" term="%22Hayward+SW%22">Hayward SW</searchLink>; Endeavor Health Research Institute, Evanston, IL, USA; Pritzker School of Medicine, University of Chicago, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Strand+DW%22">Strand DW</searchLink>; UT Southwestern Medical Center, Dallas, TX, USA.<br /><searchLink fieldCode="AU" term="%22Heer+R%22">Heer R</searchLink>; Newcastle University, Newcastle, UK; Imperial College London, London, UK.<br /><searchLink fieldCode="AU" term="%22Buskin+A%22">Buskin A</searchLink>; Newcastle University, Newcastle, UK. Electronic address: adriana.buskin@ncl.ac.uk.
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  Data: <searchLink fieldCode="JN" term="%229918227360606676%22">Cell reports methods</searchLink> [Cell Rep Methods] 2026 Jul 29, pp. 101538. <i>Date of Electronic Publication: </i>2026 Jul 29.
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