Antihistamines for atopic dermatitis (eczema): systematic review and network meta-analysis of randomised trials.

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Title: Antihistamines for atopic dermatitis (eczema): systematic review and network meta-analysis of randomised trials.
Authors: Chu AWL; Evidence in Allergy Group, McMaster University, Hamilton, ON, Canada.; Department of Medicine, McMaster University, Hamilton, ON, Canada.; Department of Medicine, University of Toronto, Toronto, ON, Canada., Wen A; Evidence in Allergy Group, McMaster University, Hamilton, ON, Canada chudk@mcmaster.ca.; Department of Medicine, McMaster University, Hamilton, ON, Canada., Guyatt GH; Department of Medicine, McMaster University, Hamilton, ON, Canada.; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada., Rao M; Evidence in Allergy Group, McMaster University, Hamilton, ON, Canada., Bakaa L; Department of Epidemiology, Harvard T H Chan School of Public Health, Boston, MA, USA., Zhao IX; Evidence in Allergy Group, McMaster University, Hamilton, ON, Canada.; Department of Medicine, McMaster University, Hamilton, ON, Canada., Roldan Y; Department of Medicine, McMaster University, Hamilton, ON, Canada.; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada., Spergel JM; Division of Allergy-Immunology, Department of Pediatrics, Children's Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA., LeBovidge J; Division of Immunology, Boston Children's Hospital, Boston, MA, USA., Boguniewicz M; Division of Allergy and Immunology, Department of Pediatrics, National Jewish Health and University of Colorado School of Medicine, Denver, CO, USA., Martin SA; UMass Chan Medical School, Worcester, MA, USA., Lind ML; Patient author, School for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, AZ, USA., Silverberg JI; Department of Dermatology, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA., Lio PA; Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA., Asiniwasis RN; Department of Dermatology, University of Saskatchewan, Regina, SK, Canada., Wang J; Division of Pediatric Allergy and Immunology, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York City, NY, USA., De Benedetto A; Department of Dermatology, University of Rochester Medical Center, Rochester, NY, USA., Greenhawt M; Asthma and Allergy Foundation of America, Arlington, VA, USA., Wheeler KE; Department of Pediatrics, University of Florida, Gainesville, FL, USA., Ong PY; Division of Clinical Immunology and Allergy, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA, USA., Frazier WT; Department of Family Medicine, UPMC St Margaret, Pittsburgh, PA, USA., Nelson H; Patient author, Department of Health Sciences, Lakehead University, Thunder Bay, ON, Canada., O'Brien M; Patient author, Tufts University School of Medicine, Boston, MA, USA., Capozza K; Public representative, Global Parents for Eczema Research, Santa Barbara, CA, USA., Begolka WS; Public representative, National Eczema Association, Novato, CA, USA., Gardner DD; Public representative, Allergy & Asthma Network, Fairfax, VA, USA., Schneider LC; Division of Immunology, Boston Children's Hospital, Boston, MA, USA., Chu DK; Evidence in Allergy Group, McMaster University, Hamilton, ON, Canada.; Department of Medicine, McMaster University, Hamilton, ON, Canada.; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.; The Research Institute of St Joe's Hamilton, St Joseph's Healthcare Hamilton, Hamilton, ON, Canada.
Source: BMJ (Clinical research ed.) [BMJ] 2026 Jul 29; Vol. 394, pp. e100163. Date of Electronic Publication: 2026 Jul 29.
Publication Type: Journal Article; Systematic Review; Network Meta-Analysis
Journal Info: Publisher: British Medical Association Country of Publication: England NLM ID: 8900488 Publication Model: Electronic Cited Medium: Internet ISSN: 1756-1833 (Electronic) Linking ISSN: 09598138 NLM ISO Abbreviation: BMJ Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Antihistamines for atopic dermatitis (eczema): systematic review and network meta-analysis of randomised trials.
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  Data: <searchLink fieldCode="AU" term="%22Chu+AWL%22">Chu AWL</searchLink>; Evidence in Allergy Group, McMaster University, Hamilton, ON, Canada.; Department of Medicine, McMaster University, Hamilton, ON, Canada.; Department of Medicine, University of Toronto, Toronto, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Wen+A%22">Wen A</searchLink>; Evidence in Allergy Group, McMaster University, Hamilton, ON, Canada chudk@mcmaster.ca.; Department of Medicine, McMaster University, Hamilton, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Guyatt+GH%22">Guyatt GH</searchLink>; Department of Medicine, McMaster University, Hamilton, ON, Canada.; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Rao+M%22">Rao M</searchLink>; Evidence in Allergy Group, McMaster University, Hamilton, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Bakaa+L%22">Bakaa L</searchLink>; Department of Epidemiology, Harvard T H Chan School of Public Health, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Zhao+IX%22">Zhao IX</searchLink>; Evidence in Allergy Group, McMaster University, Hamilton, ON, Canada.; Department of Medicine, McMaster University, Hamilton, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Roldan+Y%22">Roldan Y</searchLink>; Department of Medicine, McMaster University, Hamilton, ON, Canada.; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.<br /><searchLink fieldCode="AU" term="%22Spergel+JM%22">Spergel JM</searchLink>; Division of Allergy-Immunology, Department of Pediatrics, Children's Hospital of Philadelphia and Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22LeBovidge+J%22">LeBovidge J</searchLink>; Division of Immunology, Boston Children's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Boguniewicz+M%22">Boguniewicz M</searchLink>; Division of Allergy and Immunology, Department of Pediatrics, National Jewish Health and University of Colorado School of Medicine, Denver, CO, USA.<br /><searchLink fieldCode="AU" term="%22Martin+SA%22">Martin SA</searchLink>; UMass Chan Medical School, Worcester, MA, USA.<br /><searchLink fieldCode="AU" term="%22Lind+ML%22">Lind ML</searchLink>; Patient author, School for Engineering of Matter, Transport and Energy, Arizona State University, Tempe, AZ, USA.<br /><searchLink fieldCode="AU" term="%22Silverberg+JI%22">Silverberg JI</searchLink>; Department of Dermatology, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA.<br /><searchLink fieldCode="AU" term="%22Lio+PA%22">Lio PA</searchLink>; Department of Dermatology, Northwestern University Feinberg School of Medicine, Chicago, IL, USA.<br /><searchLink fieldCode="AU" term="%22Asiniwasis+RN%22">Asiniwasis RN</searchLink>; Department of Dermatology, University of Saskatchewan, Regina, SK, Canada.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Division of Pediatric Allergy and Immunology, Department of Pediatrics, Icahn School of Medicine at Mount Sinai, New York City, NY, USA.<br /><searchLink fieldCode="AU" term="%22De+Benedetto+A%22">De Benedetto A</searchLink>; Department of Dermatology, University of Rochester Medical Center, Rochester, NY, USA.<br /><searchLink fieldCode="AU" term="%22Greenhawt+M%22">Greenhawt M</searchLink>; Asthma and Allergy Foundation of America, Arlington, VA, USA.<br /><searchLink fieldCode="AU" term="%22Wheeler+KE%22">Wheeler KE</searchLink>; Department of Pediatrics, University of Florida, Gainesville, FL, USA.<br /><searchLink fieldCode="AU" term="%22Ong+PY%22">Ong PY</searchLink>; Division of Clinical Immunology and Allergy, Children's Hospital Los Angeles, University of Southern California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Frazier+WT%22">Frazier WT</searchLink>; Department of Family Medicine, UPMC St Margaret, Pittsburgh, PA, USA.<br /><searchLink fieldCode="AU" term="%22Nelson+H%22">Nelson H</searchLink>; Patient author, Department of Health Sciences, Lakehead University, Thunder Bay, ON, Canada.<br /><searchLink fieldCode="AU" term="%22O'Brien+M%22">O'Brien M</searchLink>; Patient author, Tufts University School of Medicine, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Capozza+K%22">Capozza K</searchLink>; Public representative, Global Parents for Eczema Research, Santa Barbara, CA, USA.<br /><searchLink fieldCode="AU" term="%22Begolka+WS%22">Begolka WS</searchLink>; Public representative, National Eczema Association, Novato, CA, USA.<br /><searchLink fieldCode="AU" term="%22Gardner+DD%22">Gardner DD</searchLink>; Public representative, Allergy & Asthma Network, Fairfax, VA, USA.<br /><searchLink fieldCode="AU" term="%22Schneider+LC%22">Schneider LC</searchLink>; Division of Immunology, Boston Children's Hospital, Boston, MA, USA.<br /><searchLink fieldCode="AU" term="%22Chu+DK%22">Chu DK</searchLink>; Evidence in Allergy Group, McMaster University, Hamilton, ON, Canada.; Department of Medicine, McMaster University, Hamilton, ON, Canada.; Department of Health Research Methods, Evidence, and Impact, McMaster University, Hamilton, ON, Canada.; The Research Institute of St Joe's Hamilton, St Joseph's Healthcare Hamilton, Hamilton, ON, Canada.
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  Data: <searchLink fieldCode="JN" term="%228900488%22">BMJ (Clinical research ed.)</searchLink> [BMJ] 2026 Jul 29; Vol. 394, pp. e100163. <i>Date of Electronic Publication: </i>2026 Jul 29.
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