Mitochondrial Dysfunction, Cerebral Metabolic Crisis, and Exploratory Bioenergetic Biomarkers in a Translational Swine Model of Acute Carbon Monoxide Poisoning.

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Title: Mitochondrial Dysfunction, Cerebral Metabolic Crisis, and Exploratory Bioenergetic Biomarkers in a Translational Swine Model of Acute Carbon Monoxide Poisoning.
Authors: Insana A; Drexel University, Philadelphia, PA 19104., Lewis A; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.; Division of Neurology, Children's Hospital of Philadelphia, Philadelphia, PA 19104., Greenwood JC; Department of Emergency Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104., Kelly M; Department of Emergency Medicine, Heersink School of Medicine, The University of Alabama at Birmingham, Birmingham, AL 35233., Shofer FS; Department of Emergency Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104., Kao SH; Resuscitation Science Center, The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104., Mason M; Resuscitation Science Center, The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104., Baak S; Resuscitation Science Center, The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104., Starr J; Resuscitation Science Center, The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104., Cabrera J; Resuscitation Science Center, The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104., Ehinger JK; Mitochondrial Medicine, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.; Otorhinolaryngology, Head and Neck Surgery, Department of Clinical Sciences Lund, Lund University, Lund, Sweden., Kilbaugh TJ; Resuscitation Science Center, The Children's Hospital of Philadelphia, Philadelphia, PA 19104.; Department of Anesthesiology and Critical Care Medicine, Children's Hospital of Philadelphia, Philadelphia, PA 19104., Ko T; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.; Division of Neurology, Children's Hospital of Philadelphia, Philadelphia, PA 19104., Viaene AN; Division of Neuropathology, Department of Pathology and Laboratory Medicine, Children's Hospital of Philadelphia, Philadelphia, PA, USA.; Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA., Baker WB; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.; Division of Neurology, Children's Hospital of Philadelphia, Philadelphia, PA 19104., Jang DH; Department of Emergency Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104.
Source: Toxicological sciences : an official journal of the Society of Toxicology [Toxicol Sci] 2026 Jul 29. Date of Electronic Publication: 2026 Jul 29.
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: United States NLM ID: 9805461 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1096-0929 (Electronic) Linking ISSN: 10960929 NLM ISO Abbreviation: Toxicol Sci Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1096-0929
DOI:10.1093/toxsci/kfag093