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Elicitation of stem-directed antibodies in rhesus macaques by a conventional hemagglutinin immunogen.

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Title: Elicitation of stem-directed antibodies in rhesus macaques by a conventional hemagglutinin immunogen.
Authors: Gu S; Infectious Diseases Division, Department of Pediatrics, Duke University, Durham, NC 27710, USA., Finney J; Laboratory of Molecular Medicine, Children's Hospital, Harvard Medical School, Boston, MA 02115, USA., Luo K; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Valencia SM; Infectious Diseases Division, Department of Pediatrics, Duke University, Durham, NC 27710, USA., Mielke D; Department of Surgery, Duke University School of Medicine, Durham, NC 27710, USA., Von Holle TA; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Marshall DJ; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Parks R; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Sutherland LL; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Scearce RM; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Wiehe K; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Santra S; Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA., Harris S; Department of Pathology, Duke University School of Medicine, Durham, NC 27710, USA., DuVall J; Department of Pathology, Duke University School of Medicine, Durham, NC 27710, USA., Landon CD; Department of Pathology, Duke University School of Medicine, Durham, NC 27710, USA., Spurrier MA; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA., Heaton NS; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA.; Duke Cancer Institute, Duke University School of Medicine, Durham, NC 27710, USA., Yassine HM; Biomedical Research Center- QU health, Qatar University, Doha Qatar., Graham BS; Department of Medicine and Microbiology, Biochemistry, & Immunology, Morehouse School of Medicine, Atlanta, GA 30310, USA., Kepler TB; Department of Microbiology, Boston University, Boston, MA 02118, USA., Liao HX; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA., Schmidt AG; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA.; Department of Microbiology, Harvard Medical School, Boston, MA 02115, USA., Ferrari G; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Surgery, Duke University School of Medicine, Durham, NC 27710, USA., Haynes BF; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Integrative Immunobiology, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA., Harrison SC; Laboratory of Molecular Medicine, Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Howard Hughes Medical Institute, Boston, MA 02115, USA., Moody MA; Infectious Diseases Division, Department of Pediatrics, Duke University, Durham, NC 27710, USA.; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Integrative Immunobiology, Duke University School of Medicine, Durham, NC 27710, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Jul 21. Date of Electronic Publication: 2026 Jul 21.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Elicitation of stem-directed antibodies in rhesus macaques by a conventional hemagglutinin immunogen.
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  Data: <searchLink fieldCode="AU" term="%22Gu+S%22">Gu S</searchLink>; Infectious Diseases Division, Department of Pediatrics, Duke University, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Finney+J%22">Finney J</searchLink>; Laboratory of Molecular Medicine, Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Luo+K%22">Luo K</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Valencia+SM%22">Valencia SM</searchLink>; Infectious Diseases Division, Department of Pediatrics, Duke University, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Mielke+D%22">Mielke D</searchLink>; Department of Surgery, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Von+Holle+TA%22">Von Holle TA</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Marshall+DJ%22">Marshall DJ</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Parks+R%22">Parks R</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Sutherland+LL%22">Sutherland LL</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Scearce+RM%22">Scearce RM</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Wiehe+K%22">Wiehe K</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Santra+S%22">Santra S</searchLink>; Beth Israel Deaconess Medical Center, Boston, MA, 02215, USA.<br /><searchLink fieldCode="AU" term="%22Harris+S%22">Harris S</searchLink>; Department of Pathology, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22DuVall+J%22">DuVall J</searchLink>; Department of Pathology, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Landon+CD%22">Landon CD</searchLink>; Department of Pathology, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Spurrier+MA%22">Spurrier MA</searchLink>; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Heaton+NS%22">Heaton NS</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Molecular Genetics and Microbiology, Duke University School of Medicine, Durham, NC 27710, USA.; Duke Cancer Institute, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Yassine+HM%22">Yassine HM</searchLink>; Biomedical Research Center- QU health, Qatar University, Doha Qatar.<br /><searchLink fieldCode="AU" term="%22Graham+BS%22">Graham BS</searchLink>; Department of Medicine and Microbiology, Biochemistry, & Immunology, Morehouse School of Medicine, Atlanta, GA 30310, USA.<br /><searchLink fieldCode="AU" term="%22Kepler+TB%22">Kepler TB</searchLink>; Department of Microbiology, Boston University, Boston, MA 02118, USA.<br /><searchLink fieldCode="AU" term="%22Liao+HX%22">Liao HX</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Schmidt+AG%22">Schmidt AG</searchLink>; Ragon Institute of MGH, MIT and Harvard, Cambridge, MA 02139, USA.; Department of Microbiology, Harvard Medical School, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Ferrari+G%22">Ferrari G</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Surgery, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Haynes+BF%22">Haynes BF</searchLink>; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Integrative Immunobiology, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Medicine, Duke University School of Medicine, Durham, NC 27710, USA.<br /><searchLink fieldCode="AU" term="%22Harrison+SC%22">Harrison SC</searchLink>; Laboratory of Molecular Medicine, Children's Hospital, Harvard Medical School, Boston, MA 02115, USA.; Howard Hughes Medical Institute, Boston, MA 02115, USA.<br /><searchLink fieldCode="AU" term="%22Moody+MA%22">Moody MA</searchLink>; Infectious Diseases Division, Department of Pediatrics, Duke University, Durham, NC 27710, USA.; Duke Human Vaccine Institute, Duke University School of Medicine, Durham, NC 27710, USA.; Department of Integrative Immunobiology, Duke University School of Medicine, Durham, NC 27710, USA.
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