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Reducing CETP activity prevents memory decline in an Alzheimer's disease mouse model.

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Title: Reducing CETP activity prevents memory decline in an Alzheimer's disease mouse model.
Authors: Phénix J; Department of Pharmacology and Therapeutics, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada.; Cell Information Systems group, Bellini Life Sciences Complex, Montreal, QC, Canada.; Centre de Recherche en Biologie Structurale (CRBS), 3649 Promenade Sir William Osler, Montreal, QC, Canada., Sarty I; Integrated Program in Neuroscience, McGill University, Montreal, QC, Canada.; Centre for Studies on the Prevention of Alzheimer's Disease, Verdun, QC, Canada.; Molecular Neurobiology Unit, Douglas Mental Health University Institute, Research Centre, Verdun, QC, Canada.; Department of Psychiatry, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada., Katz MS; Department of Biochemistry, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada.; The Rosalind & Morris Goodman Cancer Institute, McGill University, Montreal, QC, Canada., Vázquez Cobá A; Department of Pharmacology and Therapeutics, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada.; Cell Information Systems group, Bellini Life Sciences Complex, Montreal, QC, Canada.; Centre de Recherche en Biologie Structurale (CRBS), 3649 Promenade Sir William Osler, Montreal, QC, Canada.; Integrated Program in Neuroscience, McGill University, Montreal, QC, Canada., Marure Rojano AE; Department of Pharmacology and Therapeutics, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada.; Cell Information Systems group, Bellini Life Sciences Complex, Montreal, QC, Canada.; Centre de Recherche en Biologie Structurale (CRBS), 3649 Promenade Sir William Osler, Montreal, QC, Canada., Nie H; Department of Biochemistry, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada.; The Rosalind & Morris Goodman Cancer Institute, McGill University, Montreal, QC, Canada., Kerksiek A; Institute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany., Jerry I; Department of Pharmacology and Therapeutics, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada.; Cell Information Systems group, Bellini Life Sciences Complex, Montreal, QC, Canada.; Centre de Recherche en Biologie Structurale (CRBS), 3649 Promenade Sir William Osler, Montreal, QC, Canada., Berger CS; Department of Pharmacology and Therapeutics, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada.; Cell Information Systems group, Bellini Life Sciences Complex, Montreal, QC, Canada.; Centre de Recherche en Biologie Structurale (CRBS), 3649 Promenade Sir William Osler, Montreal, QC, Canada., Kiss RS; Division of Cardiology, Department of Medicine, Faculty of Medicine and Health Sciences, Research Institute of the McGill University Health Centre, McGill University, Montreal, QC, Canada., Lütjohann D; Institute of Clinical Chemistry and Clinical Pharmacology, University Hospital Bonn, Bonn, Germany., Pastor WA; Department of Biochemistry, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada.; The Rosalind & Morris Goodman Cancer Institute, McGill University, Montreal, QC, Canada., Poirier J; Centre for Studies on the Prevention of Alzheimer's Disease, Verdun, QC, Canada.; Molecular Neurobiology Unit, Douglas Mental Health University Institute, Research Centre, Verdun, QC, Canada.; Department of Psychiatry, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada., Munter LM; Department of Pharmacology and Therapeutics, Faculty of Medicine and Health Sciences, McGill University, Montreal, QC, Canada. lisa.munter@mcgill.ca.; Cell Information Systems group, Bellini Life Sciences Complex, Montreal, QC, Canada. lisa.munter@mcgill.ca.; Centre de Recherche en Biologie Structurale (CRBS), 3649 Promenade Sir William Osler, Montreal, QC, Canada. lisa.munter@mcgill.ca.; Integrated Program in Neuroscience, McGill University, Montreal, QC, Canada. lisa.munter@mcgill.ca.
Corporate Authors: PREVENT-AD Research Group
Source: EMBO molecular medicine [EMBO Mol Med] 2026 Aug 03. Date of Electronic Publication: 2026 Aug 03.
Publication Type: Journal Article
Journal Info: Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE
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