Spatial biology reveals altered macrophage states in immunosuppressed non-melanoma skin cancer.
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| Title: | Spatial biology reveals altered macrophage states in immunosuppressed non-melanoma skin cancer. |
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| Authors: | Naara S; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Kochat V; MD Anderson Epigenomics Therapy Initiative, Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Rao X; Department of Bioinformatics and Computational Biology, Division of Discovery Science, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Arslan E; MD Anderson Epigenomics Therapy Initiative, Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Saddawi-Konefka R; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Department of Otolaryngology-Head and Neck Surgery, Gleiberman Head and Neck Cancer Center, Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA., Satpati S; MD Anderson Epigenomics Therapy Initiative, Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Garbarino J; AtlasXomics, Pierce Laboratory, 290 Congress Ave, New Haven, CT, USA., Anderson JL; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Gleber-Netto FO; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: fonetto@mdanderson.org., Nagarajan P; Department of Anatomical Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: pnagarajan@mdanderson.org., Kerr TD; Department of Cancer Sciences, Cleveland Clinic Research, Cleveland Clinic, Cleveland, OH, USA., Akhter S; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Li S; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Fodor R; Department of Radiation Oncology, Cleveland Clinic, Cleveland, OH, USA., Koyfman SA; Department of Radiation Oncology, Cleveland Clinic, Cleveland, OH, USA., Yaniv D; Department of Otolaryngology, Head and Neck Surgery, Rabin Medical Center, Petah Tikva, Israel., Xie T; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Glaun M; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Bobian M; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Padron WI; MD Anderson Epigenomics Therapy Initiative, Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Ng C; AtlasXomics, Pierce Laboratory, 290 Congress Ave, New Haven, CT, USA., Gunaratne PH; Department of Biology and Biochemistry, University of Houston Sequencing Core, University of Houston, Houston, TX, USA; Department of Molecular and Cellular Biology, Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX , USA., Thevasagayampillai S; Department of Biology and Biochemistry, University of Houston Sequencing Core, University of Houston, Houston, TX, USA; Department of Molecular and Cellular Biology, Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX , USA., Migden MR; Department of Dermatology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: mrmigden@mdanderson.org., Abbas HA; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Reville PK; Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Tsai KY; Department of Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA., McGrail DJ; Department of Cancer Sciences, Cleveland Clinic Research, Cleveland Clinic, Cleveland, OH, USA. Electronic address: mcgraid@ccf.org., Wang J; Department of Bioinformatics and Computational Biology, Division of Discovery Science, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Myers JN; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Gross ND; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA., Rai K; MD Anderson Epigenomics Therapy Initiative, Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: krai@mdanderson.org., Amit M; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; UTHealth Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Cancer Neuroscience Program, UT MD Anderson Cancer Center, Houston, TX, USA. Electronic address: mamit@mdanderson.org. |
| Source: | Cell [Cell] 2026 Aug 05. Date of Electronic Publication: 2026 Aug 05. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 42556334 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Spatial biology reveals altered macrophage states in immunosuppressed non-melanoma skin cancer. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Naara+S%22">Naara S</searchLink>; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Kochat+V%22">Kochat V</searchLink>; MD Anderson Epigenomics Therapy Initiative, Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Rao+X%22">Rao X</searchLink>; Department of Bioinformatics and Computational Biology, Division of Discovery Science, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Arslan+E%22">Arslan E</searchLink>; MD Anderson Epigenomics Therapy Initiative, Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Saddawi-Konefka+R%22">Saddawi-Konefka R</searchLink>; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Department of Otolaryngology-Head and Neck Surgery, Gleiberman Head and Neck Cancer Center, Moores Cancer Center, University of California, San Diego, La Jolla, CA, USA.<br /><searchLink fieldCode="AU" term="%22Satpati+S%22">Satpati S</searchLink>; MD Anderson Epigenomics Therapy Initiative, Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Garbarino+J%22">Garbarino J</searchLink>; AtlasXomics, Pierce Laboratory, 290 Congress Ave, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Anderson+JL%22">Anderson JL</searchLink>; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Gleber-Netto+FO%22">Gleber-Netto FO</searchLink>; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: fonetto@mdanderson.org.<br /><searchLink fieldCode="AU" term="%22Nagarajan+P%22">Nagarajan P</searchLink>; Department of Anatomical Pathology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: pnagarajan@mdanderson.org.<br /><searchLink fieldCode="AU" term="%22Kerr+TD%22">Kerr TD</searchLink>; Department of Cancer Sciences, Cleveland Clinic Research, Cleveland Clinic, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Akhter+S%22">Akhter S</searchLink>; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Li+S%22">Li S</searchLink>; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Fodor+R%22">Fodor R</searchLink>; Department of Radiation Oncology, Cleveland Clinic, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Koyfman+SA%22">Koyfman SA</searchLink>; Department of Radiation Oncology, Cleveland Clinic, Cleveland, OH, USA.<br /><searchLink fieldCode="AU" term="%22Yaniv+D%22">Yaniv D</searchLink>; Department of Otolaryngology, Head and Neck Surgery, Rabin Medical Center, Petah Tikva, Israel.<br /><searchLink fieldCode="AU" term="%22Xie+T%22">Xie T</searchLink>; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Glaun+M%22">Glaun M</searchLink>; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Bobian+M%22">Bobian M</searchLink>; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Padron+WI%22">Padron WI</searchLink>; MD Anderson Epigenomics Therapy Initiative, Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Ng+C%22">Ng C</searchLink>; AtlasXomics, Pierce Laboratory, 290 Congress Ave, New Haven, CT, USA.<br /><searchLink fieldCode="AU" term="%22Gunaratne+PH%22">Gunaratne PH</searchLink>; Department of Biology and Biochemistry, University of Houston Sequencing Core, University of Houston, Houston, TX, USA; Department of Molecular and Cellular Biology, Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX , USA.<br /><searchLink fieldCode="AU" term="%22Thevasagayampillai+S%22">Thevasagayampillai S</searchLink>; Department of Biology and Biochemistry, University of Houston Sequencing Core, University of Houston, Houston, TX, USA; Department of Molecular and Cellular Biology, Human Genome Sequencing Center, Baylor College of Medicine, Houston, TX , USA.<br /><searchLink fieldCode="AU" term="%22Migden+MR%22">Migden MR</searchLink>; Department of Dermatology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: mrmigden@mdanderson.org.<br /><searchLink fieldCode="AU" term="%22Abbas+HA%22">Abbas HA</searchLink>; Department of Leukemia, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Reville+PK%22">Reville PK</searchLink>; Division of Cancer Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Tsai+KY%22">Tsai KY</searchLink>; Department of Pathology, H. Lee Moffitt Cancer Center and Research Institute, Tampa, FL, USA.<br /><searchLink fieldCode="AU" term="%22McGrail+DJ%22">McGrail DJ</searchLink>; Department of Cancer Sciences, Cleveland Clinic Research, Cleveland Clinic, Cleveland, OH, USA. Electronic address: mcgraid@ccf.org.<br /><searchLink fieldCode="AU" term="%22Wang+J%22">Wang J</searchLink>; Department of Bioinformatics and Computational Biology, Division of Discovery Science, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Myers+JN%22">Myers JN</searchLink>; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Gross+ND%22">Gross ND</searchLink>; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Rai+K%22">Rai K</searchLink>; MD Anderson Epigenomics Therapy Initiative, Department of Genomic Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. Electronic address: krai@mdanderson.org.<br /><searchLink fieldCode="AU" term="%22Amit+M%22">Amit M</searchLink>; Department of Head and Neck Surgery, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; UTHealth Graduate School of Biomedical Sciences, The University of Texas MD Anderson Cancer Center, Houston, TX, USA; Cancer Neuroscience Program, UT MD Anderson Cancer Center, Houston, TX, USA. Electronic address: mamit@mdanderson.org. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%220413066%22">Cell</searchLink> [Cell] 2026 Aug 05. <i>Date of Electronic Publication: </i>2026 Aug 05. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Cell+Press%22">Cell Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0413066 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1097-4172 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200928674%22">00928674 </searchLink><i>NLM ISO Abbreviation: </i>Cell <i>Subsets: </i>MEDLINE |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/j.cell.2026.07.031 Languages: – Code: eng Text: English Titles: – TitleFull: Spatial biology reveals altered macrophage states in immunosuppressed non-melanoma skin cancer. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Naara S – PersonEntity: Name: NameFull: Kochat V – PersonEntity: Name: NameFull: Rao X – PersonEntity: Name: NameFull: Arslan E – PersonEntity: Name: NameFull: Saddawi-Konefka R – PersonEntity: Name: NameFull: Satpati S – PersonEntity: Name: NameFull: Garbarino J – PersonEntity: Name: NameFull: Anderson JL – PersonEntity: Name: NameFull: Gleber-Netto FO – PersonEntity: Name: NameFull: Nagarajan P – PersonEntity: Name: NameFull: Kerr TD – PersonEntity: Name: NameFull: Akhter S – PersonEntity: Name: NameFull: Li S – PersonEntity: Name: NameFull: Fodor R – PersonEntity: Name: NameFull: Koyfman SA – PersonEntity: Name: NameFull: Yaniv D – PersonEntity: Name: NameFull: Xie T – PersonEntity: Name: NameFull: Glaun M – PersonEntity: Name: NameFull: Bobian M – PersonEntity: Name: NameFull: Padron WI – PersonEntity: Name: NameFull: Ng C – PersonEntity: Name: NameFull: Gunaratne PH – PersonEntity: Name: NameFull: Thevasagayampillai S – PersonEntity: Name: NameFull: Migden MR – PersonEntity: Name: NameFull: Abbas HA – PersonEntity: Name: NameFull: Reville PK – PersonEntity: Name: NameFull: Tsai KY – PersonEntity: Name: NameFull: McGrail DJ – PersonEntity: Name: NameFull: Wang J – PersonEntity: Name: NameFull: Myers JN – PersonEntity: Name: NameFull: Gross ND – PersonEntity: Name: NameFull: Rai K – PersonEntity: Name: NameFull: Amit M IsPartOfRelationships: – BibEntity: Dates: – D: 05 M: 08 Text: 2026 Aug 05 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1097-4172 Titles: – TitleFull: Cell Type: main |
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