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Palmitate promotes liver metastases by decreasing neutrophil antitumour behaviour.

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Title: Palmitate promotes liver metastases by decreasing neutrophil antitumour behaviour.
Authors: Vandekeere A; Laboratory for Tumor Evolution and Metastasis, VIB-KU Leuven Center for Cancer Biology, VIB, Herestraat 49, Leuven, Belgium.; Laboratory for Tumor Evolution and Metastasis, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium., Fernández-García J; Laboratory for Tumor Evolution and Metastasis, VIB-KU Leuven Center for Cancer Biology, VIB, Herestraat 49, Leuven, Belgium.; Laboratory for Tumor Evolution and Metastasis, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium., Peng-Winkler Y; Laboratory for Tumor Evolution and Metastasis, VIB-KU Leuven Center for Cancer Biology, VIB, Herestraat 49, Leuven, Belgium.; Laboratory for Tumor Evolution and Metastasis, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium.; Department of Gastroenterology, Hepatology and Infectious Diseases, University Hospital Dusseldorf, Dusseldorf, Germany., Martín Pérez M; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.; Department of Cell Biology, Physiology and Immunology, University of Barcelona, Barcelona, Spain.; Serra Húnter Programme (PSH), Departament de Recerca i Universitats de la Generalitat de Catalunya, Barcelona, Spain., Liu M; Laboratory for Tumor Evolution and Metastasis, VIB-KU Leuven Center for Cancer Biology, VIB, Herestraat 49, Leuven, Belgium.; Laboratory for Tumor Evolution and Metastasis, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium., Fernandes SI; Laboratory for Tumor Evolution and Metastasis, VIB-KU Leuven Center for Cancer Biology, VIB, Herestraat 49, Leuven, Belgium.; Laboratory for Tumor Evolution and Metastasis, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium., Theile J; Laboratory for Tumor Evolution and Metastasis, VIB-KU Leuven Center for Cancer Biology, VIB, Herestraat 49, Leuven, Belgium.; Laboratory for Tumor Evolution and Metastasis, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium., Willnow P; Laboratory for Tumor Evolution and Metastasis, VIB-KU Leuven Center for Cancer Biology, VIB, Herestraat 49, Leuven, Belgium.; Laboratory for Tumor Evolution and Metastasis, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium., Verheul S; Department of Surgery, Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Zels G; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium., Pabba A; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium., Desmedt C; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium., Verhoef C; Department of Surgery, Erasmus MC Cancer Institute, Rotterdam, The Netherlands., Altea-Manzano P; Laboratory for Tumor Evolution and Metastasis, VIB-KU Leuven Center for Cancer Biology, VIB, Herestraat 49, Leuven, Belgium.; Laboratory for Tumor Evolution and Metastasis, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium.; Laboratory of Metabolic Regulation and Signaling in Cancer, Andalusian Molecular Biology and Regenerative Medicine Centre (CABIMER)-University of Seville -CSIC-University Pablo de Olavide, Seville, Spain., Benitah SA; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.; Catalan Institution for Research and Advanced Studies (ICREA), Barcelona, Spain., Elia I; Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium., Malanchi I; Tumour Host Interaction laboratory, The Francis Crick Institute, London, UK., Fendt SM; Laboratory for Tumor Evolution and Metastasis, VIB-KU Leuven Center for Cancer Biology, VIB, Herestraat 49, Leuven, Belgium. sarah-maria.fendt@kuleuven.be.; Laboratory for Tumor Evolution and Metastasis, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium. sarah-maria.fendt@kuleuven.be.
Source: Nature metabolism [Nat Metab] 2026 Aug; Vol. 8 (8), pp. 1730-1750. Date of Electronic Publication: 2026 Aug 05.
Publication Type: Journal Article
Journal Info: Publisher: Springer Nature Country of Publication: Germany NLM ID: 101736592 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2522-5812 (Electronic) Linking ISSN: 25225812 NLM ISO Abbreviation: Nat Metab Subsets: MEDLINE
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  Data: Palmitate promotes liver metastases by decreasing neutrophil antitumour behaviour.
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  Data: <searchLink fieldCode="AU" term="%22Vandekeere+A%22">Vandekeere A</searchLink>; Laboratory for Tumor Evolution and Metastasis, VIB-KU Leuven Center for Cancer Biology, VIB, Herestraat 49, Leuven, Belgium.; Laboratory for Tumor Evolution and Metastasis, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Fernández-García+J%22">Fernández-García J</searchLink>; Laboratory for Tumor Evolution and Metastasis, VIB-KU Leuven Center for Cancer Biology, VIB, Herestraat 49, Leuven, Belgium.; Laboratory for Tumor Evolution and Metastasis, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Peng-Winkler+Y%22">Peng-Winkler Y</searchLink>; Laboratory for Tumor Evolution and Metastasis, VIB-KU Leuven Center for Cancer Biology, VIB, Herestraat 49, Leuven, Belgium.; Laboratory for Tumor Evolution and Metastasis, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium.; Department of Gastroenterology, Hepatology and Infectious Diseases, University Hospital Dusseldorf, Dusseldorf, Germany.<br /><searchLink fieldCode="AU" term="%22Martín+Pérez+M%22">Martín Pérez M</searchLink>; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.; Department of Cell Biology, Physiology and Immunology, University of Barcelona, Barcelona, Spain.; Serra Húnter Programme (PSH), Departament de Recerca i Universitats de la Generalitat de Catalunya, Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Liu+M%22">Liu M</searchLink>; Laboratory for Tumor Evolution and Metastasis, VIB-KU Leuven Center for Cancer Biology, VIB, Herestraat 49, Leuven, Belgium.; Laboratory for Tumor Evolution and Metastasis, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Fernandes+SI%22">Fernandes SI</searchLink>; Laboratory for Tumor Evolution and Metastasis, VIB-KU Leuven Center for Cancer Biology, VIB, Herestraat 49, Leuven, Belgium.; Laboratory for Tumor Evolution and Metastasis, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Theile+J%22">Theile J</searchLink>; Laboratory for Tumor Evolution and Metastasis, VIB-KU Leuven Center for Cancer Biology, VIB, Herestraat 49, Leuven, Belgium.; Laboratory for Tumor Evolution and Metastasis, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Willnow+P%22">Willnow P</searchLink>; Laboratory for Tumor Evolution and Metastasis, VIB-KU Leuven Center for Cancer Biology, VIB, Herestraat 49, Leuven, Belgium.; Laboratory for Tumor Evolution and Metastasis, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Verheul+S%22">Verheul S</searchLink>; Department of Surgery, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Zels+G%22">Zels G</searchLink>; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Pabba+A%22">Pabba A</searchLink>; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Desmedt+C%22">Desmedt C</searchLink>; Laboratory for Translational Breast Cancer Research, Department of Oncology, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Verhoef+C%22">Verhoef C</searchLink>; Department of Surgery, Erasmus MC Cancer Institute, Rotterdam, The Netherlands.<br /><searchLink fieldCode="AU" term="%22Altea-Manzano+P%22">Altea-Manzano P</searchLink>; Laboratory for Tumor Evolution and Metastasis, VIB-KU Leuven Center for Cancer Biology, VIB, Herestraat 49, Leuven, Belgium.; Laboratory for Tumor Evolution and Metastasis, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium.; Laboratory of Metabolic Regulation and Signaling in Cancer, Andalusian Molecular Biology and Regenerative Medicine Centre (CABIMER)-University of Seville -CSIC-University Pablo de Olavide, Seville, Spain.<br /><searchLink fieldCode="AU" term="%22Benitah+SA%22">Benitah SA</searchLink>; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.; Catalan Institution for Research and Advanced Studies (ICREA), Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Elia+I%22">Elia I</searchLink>; Department of Cellular and Molecular Medicine, KU Leuven, Leuven, Belgium.<br /><searchLink fieldCode="AU" term="%22Malanchi+I%22">Malanchi I</searchLink>; Tumour Host Interaction laboratory, The Francis Crick Institute, London, UK.<br /><searchLink fieldCode="AU" term="%22Fendt+SM%22">Fendt SM</searchLink>; Laboratory for Tumor Evolution and Metastasis, VIB-KU Leuven Center for Cancer Biology, VIB, Herestraat 49, Leuven, Belgium. sarah-maria.fendt@kuleuven.be.; Laboratory for Tumor Evolution and Metastasis, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium. sarah-maria.fendt@kuleuven.be.
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  Data: <searchLink fieldCode="JN" term="%22101736592%22">Nature metabolism</searchLink> [Nat Metab] 2026 Aug; Vol. 8 (8), pp. 1730-1750. <i>Date of Electronic Publication: </i>2026 Aug 05.
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