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Fc-optimized GITR antibody enhances a CD4 T cell-dendritic cell crosstalk to promote antitumor immunity.

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Title: Fc-optimized GITR antibody enhances a CD4 T cell-dendritic cell crosstalk to promote antitumor immunity.
Authors: Avraham Y; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel., Barth N; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel., Yair Bar-On T; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel., Toval B; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel., Habshush Menachem A; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel., Blanga J; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel., Herzog E; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel., Rotem H; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel., Shapir Itai Y; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel., Feferman T; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel., Biton M; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel., Dahan R; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel. rony.dahan@weizmann.ac.il.
Source: Nature cancer [Nat Cancer] 2026 Aug 05. Date of Electronic Publication: 2026 Aug 05.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101761119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2662-1347 (Electronic) Linking ISSN: 26621347 NLM ISO Abbreviation: Nat Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Fc-optimized GITR antibody enhances a CD4 T cell-dendritic cell crosstalk to promote antitumor immunity.
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  Data: <searchLink fieldCode="AU" term="%22Avraham+Y%22">Avraham Y</searchLink>; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Barth+N%22">Barth N</searchLink>; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Yair+Bar-On+T%22">Yair Bar-On T</searchLink>; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Toval+B%22">Toval B</searchLink>; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Habshush+Menachem+A%22">Habshush Menachem A</searchLink>; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Blanga+J%22">Blanga J</searchLink>; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Herzog+E%22">Herzog E</searchLink>; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Rotem+H%22">Rotem H</searchLink>; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Shapir+Itai+Y%22">Shapir Itai Y</searchLink>; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Feferman+T%22">Feferman T</searchLink>; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Biton+M%22">Biton M</searchLink>; Department of Immunology and Regenerative Biology, Weizmann Institute of Science, Rehovot, Israel.<br /><searchLink fieldCode="AU" term="%22Dahan+R%22">Dahan R</searchLink>; Department of Systems Immunology, Weizmann Institute of Science, Rehovot, Israel. rony.dahan@weizmann.ac.il.
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  Data: <searchLink fieldCode="JN" term="%22101761119%22">Nature cancer</searchLink> [Nat Cancer] 2026 Aug 05. <i>Date of Electronic Publication: </i>2026 Aug 05.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101761119 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2662-1347 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2226621347%22">26621347 </searchLink><i>NLM ISO Abbreviation: </i>Nat Cancer <i>Subsets: </i>MEDLINE
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        Value: 10.1038/s43018-026-01207-1
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              Text: 2026 Aug 05
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