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Prediction of MGMT promoter methylation in glioblastoma and grade 4 astrocytoma using fluid-suppressed chemical exchange saturation transfer MRI and machine learning-based segmentation.

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Title: Prediction of MGMT promoter methylation in glioblastoma and grade 4 astrocytoma using fluid-suppressed chemical exchange saturation transfer MRI and machine learning-based segmentation.
Authors: Salomonsson T; Division of Radiology, Department of Clinical Sciences, Lund University, Lund, Sweden., Zahirovic E; Division of Radiology, Department of Clinical Sciences, Lund University, Lund, Sweden., Knutsson M; Division of Radiology, Department of Clinical Sciences, Lund University, Lund, Sweden., Seidemo A; Division of Radiology, Department of Clinical Sciences, Lund University, Lund, Sweden.; BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Saenz Sarda X; Division of Pathology, Department of Clinical Sciences, Lund University, Lund, Sweden., Liebig P; Advanced Systems, Magnetic Resonance, Siemens Healthineers AG, Erlangen, Germany., Casagranda S; Innovation Lab, Olea Medical, La Ciotat, France., Lätt J; Department of Medical Imaging and Physiology, Skåne University Hospital, Lund, Sweden., Rydelius A; Division of Neurology, Department of Clinical Sciences, Lund University, Lund, Sweden., Bengzon J; Division of Neurosurgery and Kamprad Laboratory, Department of Clinical Sciences, Lund University, Lund, Sweden., van Zijl PCM; F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, United States.; Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, United States., Knutsson L; F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, United States.; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, United States.; Department of Medical Radiation Physics, Lund University, Lund, Sweden., Sundgren PC; Division of Radiology, Department of Clinical Sciences, Lund University, Lund, Sweden.; Department of Medical Imaging and Physiology, Skåne University Hospital, Lund, Sweden.; Lund University Bioimaging Center (LBIC), Lund University, Lund, Sweden.
Source: Frontiers in oncology [Front Oncol] 2026 Jul 23; Vol. 16, pp. 1829071. Date of Electronic Publication: 2026 Jul 23 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101568867 Publication Model: eCollection Cited Medium: Print ISSN: 2234-943X (Print) Linking ISSN: 2234943X NLM ISO Abbreviation: Front Oncol Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: Prediction of MGMT promoter methylation in glioblastoma and grade 4 astrocytoma using fluid-suppressed chemical exchange saturation transfer MRI and machine learning-based segmentation.
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  Data: <searchLink fieldCode="AU" term="%22Salomonsson+T%22">Salomonsson T</searchLink>; Division of Radiology, Department of Clinical Sciences, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Zahirovic+E%22">Zahirovic E</searchLink>; Division of Radiology, Department of Clinical Sciences, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Knutsson+M%22">Knutsson M</searchLink>; Division of Radiology, Department of Clinical Sciences, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Seidemo+A%22">Seidemo A</searchLink>; Division of Radiology, Department of Clinical Sciences, Lund University, Lund, Sweden.; BioMedical Engineering and Imaging Institute, Icahn School of Medicine at Mount Sinai, New York, NY, United States.<br /><searchLink fieldCode="AU" term="%22Saenz+Sarda+X%22">Saenz Sarda X</searchLink>; Division of Pathology, Department of Clinical Sciences, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Liebig+P%22">Liebig P</searchLink>; Advanced Systems, Magnetic Resonance, Siemens Healthineers AG, Erlangen, Germany.<br /><searchLink fieldCode="AU" term="%22Casagranda+S%22">Casagranda S</searchLink>; Innovation Lab, Olea Medical, La Ciotat, France.<br /><searchLink fieldCode="AU" term="%22Lätt+J%22">Lätt J</searchLink>; Department of Medical Imaging and Physiology, Skåne University Hospital, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Rydelius+A%22">Rydelius A</searchLink>; Division of Neurology, Department of Clinical Sciences, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Bengzon+J%22">Bengzon J</searchLink>; Division of Neurosurgery and Kamprad Laboratory, Department of Clinical Sciences, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22van+Zijl+PCM%22">van Zijl PCM</searchLink>; F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, United States.; Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, MD, United States.<br /><searchLink fieldCode="AU" term="%22Knutsson+L%22">Knutsson L</searchLink>; F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, United States.; Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, United States.; Department of Medical Radiation Physics, Lund University, Lund, Sweden.<br /><searchLink fieldCode="AU" term="%22Sundgren+PC%22">Sundgren PC</searchLink>; Division of Radiology, Department of Clinical Sciences, Lund University, Lund, Sweden.; Department of Medical Imaging and Physiology, Skåne University Hospital, Lund, Sweden.; Lund University Bioimaging Center (LBIC), Lund University, Lund, Sweden.
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