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In silico framework for benchmarking optogenetic hearing restoration.

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Title: In silico framework for benchmarking optogenetic hearing restoration.
Authors: Khurana L; University Medical Center Göttingen, Institute for Auditory Neuroscience, Göttingen, Germany.; Auditory Neuroscience and Optogenetics Laboratory, German Primate Center, Göttingen, Germany.; Auditory Neuroscience & Synaptic Nanophysiology Group, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.; Junior Research Group 'Computational Neuroscience and Neuroengineering', Göttingen, Germany.; University of Göttingen, The doctoral program 'Sensory and Motor Neuroscience', Göttingen Graduate Center for Neurosciences, Biophysics, and Molecular Biosciences (GGNB), Göttingen, Germany., Nejedly P; University Medical Center Göttingen, Institute for Auditory Neuroscience, Göttingen, Germany.; Auditory Neuroscience and Optogenetics Laboratory, German Primate Center, Göttingen, Germany.; University of Göttingen, International Max Planck Research School for Neurosciences (IMPRS), Göttingen Graduate School for Neurosciences, Biophysics, and Molecular Biosciences (GGNB), Göttingen, Germany., Zhang Y; Hannover Medical School (MHH), Hannover, Germany.; Cluster of Excellence 'Hearing4All', Hannover, Germany., Jagger DJ; Centre for Auditory Research, UCL Ear Institute, University College London, London, United Kingdom., Nogueira W; Hannover Medical School (MHH), Hannover, Germany.; Cluster of Excellence 'Hearing4All', Hannover, Germany.; Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain.; Department of Microelectronics and Electronic Systems, Institute of Neuroscience, Universitat Autonoma de Barcelona, Spain., Moser T; University Medical Center Göttingen, Institute for Auditory Neuroscience, Göttingen, Germany.; Auditory Neuroscience and Optogenetics Laboratory, German Primate Center, Göttingen, Germany.; Auditory Neuroscience & Synaptic Nanophysiology Group, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.; University Medical Center Göttingen, InnerEarLab, Göttingen, Germany.; University of Göttingen, Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), Göttingen, Germany.; University of Göttingen, Collaborative Research Center 1690 (CRC1690), Göttingen, Germany.; University Medical Center Göttingen, Else Kröner Fresenius Center for Optogenetic Therapies, 37075 Göttingen, Germany., Jablonski L; University Medical Center Göttingen, Institute for Auditory Neuroscience, Göttingen, Germany.; Auditory Neuroscience and Optogenetics Laboratory, German Primate Center, Göttingen, Germany.; Junior Research Group 'Computational Neuroscience and Neuroengineering', Göttingen, Germany.; University Medical Center Göttingen, InnerEarLab, Göttingen, Germany.; University Medical Center Göttingen, Else Kröner Fresenius Center for Optogenetic Therapies, 37075 Göttingen, Germany.
Source: Journal of neural engineering [J Neural Eng] 2026 Sep 24; Vol. 23 (5). Date of Electronic Publication: 2026 Sep 24.
Publication Type: Journal Article
Journal Info: Publisher: Institute of Physics Pub Country of Publication: England NLM ID: 101217933 Publication Model: Electronic Cited Medium: Internet ISSN: 1741-2552 (Electronic) Linking ISSN: 17412552 NLM ISO Abbreviation: J Neural Eng Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Khurana+L%22">Khurana L</searchLink>; University Medical Center Göttingen, Institute for Auditory Neuroscience, Göttingen, Germany.; Auditory Neuroscience and Optogenetics Laboratory, German Primate Center, Göttingen, Germany.; Auditory Neuroscience & Synaptic Nanophysiology Group, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.; Junior Research Group 'Computational Neuroscience and Neuroengineering', Göttingen, Germany.; University of Göttingen, The doctoral program 'Sensory and Motor Neuroscience', Göttingen Graduate Center for Neurosciences, Biophysics, and Molecular Biosciences (GGNB), Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Nejedly+P%22">Nejedly P</searchLink>; University Medical Center Göttingen, Institute for Auditory Neuroscience, Göttingen, Germany.; Auditory Neuroscience and Optogenetics Laboratory, German Primate Center, Göttingen, Germany.; University of Göttingen, International Max Planck Research School for Neurosciences (IMPRS), Göttingen Graduate School for Neurosciences, Biophysics, and Molecular Biosciences (GGNB), Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; Hannover Medical School (MHH), Hannover, Germany.; Cluster of Excellence 'Hearing4All', Hannover, Germany.<br /><searchLink fieldCode="AU" term="%22Jagger+DJ%22">Jagger DJ</searchLink>; Centre for Auditory Research, UCL Ear Institute, University College London, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Nogueira+W%22">Nogueira W</searchLink>; Hannover Medical School (MHH), Hannover, Germany.; Cluster of Excellence 'Hearing4All', Hannover, Germany.; Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain.; Department of Microelectronics and Electronic Systems, Institute of Neuroscience, Universitat Autonoma de Barcelona, Spain.<br /><searchLink fieldCode="AU" term="%22Moser+T%22">Moser T</searchLink>; University Medical Center Göttingen, Institute for Auditory Neuroscience, Göttingen, Germany.; Auditory Neuroscience and Optogenetics Laboratory, German Primate Center, Göttingen, Germany.; Auditory Neuroscience & Synaptic Nanophysiology Group, Max Planck Institute for Multidisciplinary Sciences, Göttingen, Germany.; University Medical Center Göttingen, InnerEarLab, Göttingen, Germany.; University of Göttingen, Cluster of Excellence 'Multiscale Bioimaging: from Molecular Machines to Networks of Excitable Cells' (MBExC), Göttingen, Germany.; University of Göttingen, Collaborative Research Center 1690 (CRC1690), Göttingen, Germany.; University Medical Center Göttingen, Else Kröner Fresenius Center for Optogenetic Therapies, 37075 Göttingen, Germany.<br /><searchLink fieldCode="AU" term="%22Jablonski+L%22">Jablonski L</searchLink>; University Medical Center Göttingen, Institute for Auditory Neuroscience, Göttingen, Germany.; Auditory Neuroscience and Optogenetics Laboratory, German Primate Center, Göttingen, Germany.; Junior Research Group 'Computational Neuroscience and Neuroengineering', Göttingen, Germany.; University Medical Center Göttingen, InnerEarLab, Göttingen, Germany.; University Medical Center Göttingen, Else Kröner Fresenius Center for Optogenetic Therapies, 37075 Göttingen, Germany.
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              Text: 2026 Sep 24
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