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WF-1801: Single-arm pilot study of ramipril for prevention of radiation-induced cognitive decline in glioblastoma patients receiving chemoradiotherapy.

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Title: WF-1801: Single-arm pilot study of ramipril for prevention of radiation-induced cognitive decline in glioblastoma patients receiving chemoradiotherapy.
Authors: Cramer CK; Department of Radiation Oncology, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Smith S; Department of Biostatistics and Data Science, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Dressler EV; Department of Biostatistics and Data Science, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Page B; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins School of Medicine, Baltimore, MD, USA., Wefel JS; Department of Neuro-Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA., Rapp SR; Department of Psychiatry and Behavioral Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA.; Department of Social Sciences and Health Policy, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Ip EH; Department of Biostatistics and Data Science, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Pugh SL; Department of Statistics, American College of Radiology, NRG Oncology Statistics and Data Management Center, Philadelphia, PA, USA., Sumrall A; Department of Cancer Medicine, Wake Forest University School of Medicine, Charlotte, NC, USA., Strowd RE; Department of Neurology, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Vaslow ZK; Department of Neuro-Oncology, Cone Health Cancer Center, Greensboro, NC, USA., Volas-Redd G; Georgia Cancer Specialists, Northside Hospital Cancer Institute, Atlanta, GA, USA., Weaver KE; Department of Social Sciences and Health Policy, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Lesser GJ; Department of Cancer Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA., Chan MD; Department of Radiation Oncology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
Source: Neuro-oncology practice [Neurooncol Pract] 2026 May 22; Vol. 13 (5), pp. 962-972. Date of Electronic Publication: 2026 May 22 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Oxford University Press Country of Publication: England NLM ID: 101640528 Publication Model: eCollection Cited Medium: Print ISSN: 2054-2577 (Print) Linking ISSN: 20542577 NLM ISO Abbreviation: Neurooncol Pract Subsets: PubMed not MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Cramer+CK%22">Cramer CK</searchLink>; Department of Radiation Oncology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.<br /><searchLink fieldCode="AU" term="%22Smith+S%22">Smith S</searchLink>; Department of Biostatistics and Data Science, Wake Forest University School of Medicine, Winston-Salem, NC, USA.<br /><searchLink fieldCode="AU" term="%22Dressler+EV%22">Dressler EV</searchLink>; Department of Biostatistics and Data Science, Wake Forest University School of Medicine, Winston-Salem, NC, USA.<br /><searchLink fieldCode="AU" term="%22Page+B%22">Page B</searchLink>; Department of Radiation Oncology and Molecular Radiation Sciences, Johns Hopkins School of Medicine, Baltimore, MD, USA.<br /><searchLink fieldCode="AU" term="%22Wefel+JS%22">Wefel JS</searchLink>; Department of Neuro-Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.; Department of Radiation Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA.<br /><searchLink fieldCode="AU" term="%22Rapp+SR%22">Rapp SR</searchLink>; Department of Psychiatry and Behavioral Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA.; Department of Social Sciences and Health Policy, Wake Forest University School of Medicine, Winston-Salem, NC, USA.<br /><searchLink fieldCode="AU" term="%22Ip+EH%22">Ip EH</searchLink>; Department of Biostatistics and Data Science, Wake Forest University School of Medicine, Winston-Salem, NC, USA.<br /><searchLink fieldCode="AU" term="%22Pugh+SL%22">Pugh SL</searchLink>; Department of Statistics, American College of Radiology, NRG Oncology Statistics and Data Management Center, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Sumrall+A%22">Sumrall A</searchLink>; Department of Cancer Medicine, Wake Forest University School of Medicine, Charlotte, NC, USA.<br /><searchLink fieldCode="AU" term="%22Strowd+RE%22">Strowd RE</searchLink>; Department of Neurology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.<br /><searchLink fieldCode="AU" term="%22Vaslow+ZK%22">Vaslow ZK</searchLink>; Department of Neuro-Oncology, Cone Health Cancer Center, Greensboro, NC, USA.<br /><searchLink fieldCode="AU" term="%22Volas-Redd+G%22">Volas-Redd G</searchLink>; Georgia Cancer Specialists, Northside Hospital Cancer Institute, Atlanta, GA, USA.<br /><searchLink fieldCode="AU" term="%22Weaver+KE%22">Weaver KE</searchLink>; Department of Social Sciences and Health Policy, Wake Forest University School of Medicine, Winston-Salem, NC, USA.<br /><searchLink fieldCode="AU" term="%22Lesser+GJ%22">Lesser GJ</searchLink>; Department of Cancer Medicine, Wake Forest University School of Medicine, Winston-Salem, NC, USA.<br /><searchLink fieldCode="AU" term="%22Chan+MD%22">Chan MD</searchLink>; Department of Radiation Oncology, Wake Forest University School of Medicine, Winston-Salem, NC, USA.
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