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A founder population reveals genetic variation with major effect on serious mental illness.

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Title: A founder population reveals genetic variation with major effect on serious mental illness.
Authors: Gerdes G; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, USA., Tozzo V; Department of Computational Medicine, David Geffen School of Medicine, UCLA, Los Angeles, California, USA., Service SK; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, USA., Frydman-Gani C; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, USA., Diaz-Zuluaga AM; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, USA.; BD2: Breakthrough Discoveries for Thriving with Bipolar Disorder, Santa Monica, California, USA., Valencia-Echeverry J; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia., Arias A; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia., Bicks LK; Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA., Ramirez-Diaz AM; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, USA., Sealock JM; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.; Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Liao C; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.; Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Howrigan DP; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.; Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Liu C; Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Lopera-Maya EA; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, USA., Pimplaskar A; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, USA., De la Hoz JF; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, USA.; Center for Precision Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA., Arango-Gómez MA; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia., Arango-Restrepo C; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia., Arbelaez-Herrera MC; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia., Camacho-Gualteros K; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia., Cardona-Arango M; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia., Castaño-Ramirez M; Department of Mental Health and Human Behavior, Universidad de Caldas, Colombia., Castañeda-Hoyos JA; Data Engineering Lead, Center for Biosciences, SURA, Colombia., Cerrato F; Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Chapman SB; Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Franco-Gómez RE; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia., Londoño-Martinez JD; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia., Mazo-Morales JS; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia., Mejía-Piedrahita JC; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia., Mir E; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, USA., Moore TM; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Lifespan Brain Institute (LiBI) of Penn Medicine and CHOP, University of Pennsylvania, Philadelphia, PA, USA., Perez-Jaramillo LE; Director of Epidemiology and Data Science, Center for Biosciences, SURA, Colombia., Pérez-Vallejo M; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia., Posada-Ricardo ME; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia., Riscanevo-Posada V; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia., Restrepo-Osorio C; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia., Restrepo-Osorio D; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia., Ruparel K; Neurodevelopment and Psychosis Section, Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA., Sánchez-Patiño D; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia., Teshiba T; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, USA., Valdez J; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, USA., Valencia-Londoño W; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia., Valencia-Zuluaga OA; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia., Velez-Arango JM; Center for Biosciences, SURA, Colombia., Crossley NA; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia.; Department of Psychiatry, Pontificia Universidad Católica de Chile, Santiago, Chile.; Centro de Interés Nacional para Investigación e Innovación en Niñez, Adolescencia, Resiliencia y Adversidad (IINARA), Santiago, Chile., Palacio-Ortiz JD; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia.; Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia., Geschwind DH; Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.; Center for Autism Research and Treatment, Semel Institute, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.; Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.; Institute for Precision Health, University of California Los Angeles, Los Angeles, CA, USA., Martin AR; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.; Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Gur RC; Lifespan Brain Institute (LiBI) of Penn Medicine and CHOP, University of Pennsylvania, Philadelphia, PA, USA.; Brain Behavior Laboratory, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA., Sawaya MR; Department of Biological Chemistry, University of California, Los Angeles, CA, USA.; Department of Chemistry and Biochemistry, University of California, Los Angeles, CA, USA.; Department of Energy Institute for Genomics and Proteomics, University of California, Los Angeles, CA, USA.; Molecular Biology Institute, University of California, Los Angeles, CA, USA., Eisenberg DS; Department of Biological Chemistry, University of California, Los Angeles, CA, USA.; Department of Chemistry and Biochemistry, University of California, Los Angeles, CA, USA.; Department of Energy Institute for Genomics and Proteomics, University of California, Los Angeles, CA, USA.; Molecular Biology Institute, University of California, Los Angeles, CA, USA., Escobar JI; Rutgers University, New Brunswick, NJ, USA., Sabatti C; Department of Biomedical Data Science, Stanford, CA, USA., Reus VI; Department of Psychiatry and Behavioral Sciences, School of Medicine, University of California, San Francisco, San Francisco, California, USA., Bearden CE; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, USA.; Department of Psychology, University of California Los Angeles, Los Angeles, California, USA., Neale BM; BD2: Breakthrough Discoveries for Thriving with Bipolar Disorder, Santa Monica, California, USA.; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.; Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA., Lopez-Jaramillo C; BD2: Breakthrough Discoveries for Thriving with Bipolar Disorder, Santa Monica, California, USA.; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia.; Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia., Freimer NB; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, USA.; BD2: Breakthrough Discoveries for Thriving with Bipolar Disorder, Santa Monica, California, USA.; Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.; Institute for Precision Health, University of California Los Angeles, Los Angeles, CA, USA., Olde Loohuis LM; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, USA.; Department of Computational Medicine, David Geffen School of Medicine, UCLA, Los Angeles, California, USA.; BD2: Breakthrough Discoveries for Thriving with Bipolar Disorder, Santa Monica, California, USA.; Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.; Department of Psychiatry, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA.
Source: MedRxiv : the preprint server for health sciences [medRxiv] 2026 Sep 27. Date of Electronic Publication: 2026 Sep 27.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
FullText Text:
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Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 42818201
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
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Items – Name: Title
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  Data: A founder population reveals genetic variation with major effect on serious mental illness.
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  Data: <searchLink fieldCode="AU" term="%22Gerdes+G%22">Gerdes G</searchLink>; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, USA.<br /><searchLink fieldCode="AU" term="%22Tozzo+V%22">Tozzo V</searchLink>; Department of Computational Medicine, David Geffen School of Medicine, UCLA, Los Angeles, California, USA.<br /><searchLink fieldCode="AU" term="%22Service+SK%22">Service SK</searchLink>; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, USA.<br /><searchLink fieldCode="AU" term="%22Frydman-Gani+C%22">Frydman-Gani C</searchLink>; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, USA.<br /><searchLink fieldCode="AU" term="%22Diaz-Zuluaga+AM%22">Diaz-Zuluaga AM</searchLink>; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, USA.; BD2: Breakthrough Discoveries for Thriving with Bipolar Disorder, Santa Monica, California, USA.<br /><searchLink fieldCode="AU" term="%22Valencia-Echeverry+J%22">Valencia-Echeverry J</searchLink>; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia.<br /><searchLink fieldCode="AU" term="%22Arias+A%22">Arias A</searchLink>; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia.<br /><searchLink fieldCode="AU" term="%22Bicks+LK%22">Bicks LK</searchLink>; Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Ramirez-Diaz+AM%22">Ramirez-Diaz AM</searchLink>; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, USA.<br /><searchLink fieldCode="AU" term="%22Sealock+JM%22">Sealock JM</searchLink>; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.; Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Liao+C%22">Liao C</searchLink>; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.; Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Howrigan+DP%22">Howrigan DP</searchLink>; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.; Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Liu+C%22">Liu C</searchLink>; Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Lopera-Maya+EA%22">Lopera-Maya EA</searchLink>; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, USA.<br /><searchLink fieldCode="AU" term="%22Pimplaskar+A%22">Pimplaskar A</searchLink>; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, USA.<br /><searchLink fieldCode="AU" term="%22De+la+Hoz+JF%22">De la Hoz JF</searchLink>; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, USA.; Center for Precision Psychiatry, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.; Center for Genomic Medicine, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Arango-Gómez+MA%22">Arango-Gómez MA</searchLink>; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia.<br /><searchLink fieldCode="AU" term="%22Arango-Restrepo+C%22">Arango-Restrepo C</searchLink>; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia.<br /><searchLink fieldCode="AU" term="%22Arbelaez-Herrera+MC%22">Arbelaez-Herrera MC</searchLink>; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia.<br /><searchLink fieldCode="AU" term="%22Camacho-Gualteros+K%22">Camacho-Gualteros K</searchLink>; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia.<br /><searchLink fieldCode="AU" term="%22Cardona-Arango+M%22">Cardona-Arango M</searchLink>; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia.<br /><searchLink fieldCode="AU" term="%22Castaño-Ramirez+M%22">Castaño-Ramirez M</searchLink>; Department of Mental Health and Human Behavior, Universidad de Caldas, Colombia.<br /><searchLink fieldCode="AU" term="%22Castañeda-Hoyos+JA%22">Castañeda-Hoyos JA</searchLink>; Data Engineering Lead, Center for Biosciences, SURA, Colombia.<br /><searchLink fieldCode="AU" term="%22Cerrato+F%22">Cerrato F</searchLink>; Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Chapman+SB%22">Chapman SB</searchLink>; Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Franco-Gómez+RE%22">Franco-Gómez RE</searchLink>; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia.<br /><searchLink fieldCode="AU" term="%22Londoño-Martinez+JD%22">Londoño-Martinez JD</searchLink>; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia.<br /><searchLink fieldCode="AU" term="%22Mazo-Morales+JS%22">Mazo-Morales JS</searchLink>; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia.<br /><searchLink fieldCode="AU" term="%22Mejía-Piedrahita+JC%22">Mejía-Piedrahita JC</searchLink>; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia.<br /><searchLink fieldCode="AU" term="%22Mir+E%22">Mir E</searchLink>; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, USA.<br /><searchLink fieldCode="AU" term="%22Moore+TM%22">Moore TM</searchLink>; Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.; Lifespan Brain Institute (LiBI) of Penn Medicine and CHOP, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Perez-Jaramillo+LE%22">Perez-Jaramillo LE</searchLink>; Director of Epidemiology and Data Science, Center for Biosciences, SURA, Colombia.<br /><searchLink fieldCode="AU" term="%22Pérez-Vallejo+M%22">Pérez-Vallejo M</searchLink>; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia.<br /><searchLink fieldCode="AU" term="%22Posada-Ricardo+ME%22">Posada-Ricardo ME</searchLink>; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia.<br /><searchLink fieldCode="AU" term="%22Riscanevo-Posada+V%22">Riscanevo-Posada V</searchLink>; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia.<br /><searchLink fieldCode="AU" term="%22Restrepo-Osorio+C%22">Restrepo-Osorio C</searchLink>; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia.<br /><searchLink fieldCode="AU" term="%22Restrepo-Osorio+D%22">Restrepo-Osorio D</searchLink>; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia.<br /><searchLink fieldCode="AU" term="%22Ruparel+K%22">Ruparel K</searchLink>; Neurodevelopment and Psychosis Section, Department of Psychiatry, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Sánchez-Patiño+D%22">Sánchez-Patiño D</searchLink>; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia.<br /><searchLink fieldCode="AU" term="%22Teshiba+T%22">Teshiba T</searchLink>; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, USA.<br /><searchLink fieldCode="AU" term="%22Valdez+J%22">Valdez J</searchLink>; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, USA.<br /><searchLink fieldCode="AU" term="%22Valencia-Londoño+W%22">Valencia-Londoño W</searchLink>; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia.<br /><searchLink fieldCode="AU" term="%22Valencia-Zuluaga+OA%22">Valencia-Zuluaga OA</searchLink>; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia.<br /><searchLink fieldCode="AU" term="%22Velez-Arango+JM%22">Velez-Arango JM</searchLink>; Center for Biosciences, SURA, Colombia.<br /><searchLink fieldCode="AU" term="%22Crossley+NA%22">Crossley NA</searchLink>; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia.; Department of Psychiatry, Pontificia Universidad Católica de Chile, Santiago, Chile.; Centro de Interés Nacional para Investigación e Innovación en Niñez, Adolescencia, Resiliencia y Adversidad (IINARA), Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Palacio-Ortiz+JD%22">Palacio-Ortiz JD</searchLink>; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia.; Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia.<br /><searchLink fieldCode="AU" term="%22Geschwind+DH%22">Geschwind DH</searchLink>; Program in Neurogenetics, Department of Neurology, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.; Center for Autism Research and Treatment, Semel Institute, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.; Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.; Institute for Precision Health, University of California Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Martin+AR%22">Martin AR</searchLink>; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.; Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Gur+RC%22">Gur RC</searchLink>; Lifespan Brain Institute (LiBI) of Penn Medicine and CHOP, University of Pennsylvania, Philadelphia, PA, USA.; Brain Behavior Laboratory, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA, USA.<br /><searchLink fieldCode="AU" term="%22Sawaya+MR%22">Sawaya MR</searchLink>; Department of Biological Chemistry, University of California, Los Angeles, CA, USA.; Department of Chemistry and Biochemistry, University of California, Los Angeles, CA, USA.; Department of Energy Institute for Genomics and Proteomics, University of California, Los Angeles, CA, USA.; Molecular Biology Institute, University of California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Eisenberg+DS%22">Eisenberg DS</searchLink>; Department of Biological Chemistry, University of California, Los Angeles, CA, USA.; Department of Chemistry and Biochemistry, University of California, Los Angeles, CA, USA.; Department of Energy Institute for Genomics and Proteomics, University of California, Los Angeles, CA, USA.; Molecular Biology Institute, University of California, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Escobar+JI%22">Escobar JI</searchLink>; Rutgers University, New Brunswick, NJ, USA.<br /><searchLink fieldCode="AU" term="%22Sabatti+C%22">Sabatti C</searchLink>; Department of Biomedical Data Science, Stanford, CA, USA.<br /><searchLink fieldCode="AU" term="%22Reus+VI%22">Reus VI</searchLink>; Department of Psychiatry and Behavioral Sciences, School of Medicine, University of California, San Francisco, San Francisco, California, USA.<br /><searchLink fieldCode="AU" term="%22Bearden+CE%22">Bearden CE</searchLink>; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, USA.; Department of Psychology, University of California Los Angeles, Los Angeles, California, USA.<br /><searchLink fieldCode="AU" term="%22Neale+BM%22">Neale BM</searchLink>; BD2: Breakthrough Discoveries for Thriving with Bipolar Disorder, Santa Monica, California, USA.; Analytic and Translational Genetics Unit, Department of Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA.; Stanley Center for Psychiatric Research, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Program in Medical and Population Genetics, The Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.<br /><searchLink fieldCode="AU" term="%22Lopez-Jaramillo+C%22">Lopez-Jaramillo C</searchLink>; BD2: Breakthrough Discoveries for Thriving with Bipolar Disorder, Santa Monica, California, USA.; Research Group in Psychiatry, Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia.; Department of Psychiatry, School of Medicine, Universidad de Antioquia, Medellín, Antioquia, Colombia.<br /><searchLink fieldCode="AU" term="%22Freimer+NB%22">Freimer NB</searchLink>; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, USA.; BD2: Breakthrough Discoveries for Thriving with Bipolar Disorder, Santa Monica, California, USA.; Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.; Institute for Precision Health, University of California Los Angeles, Los Angeles, CA, USA.<br /><searchLink fieldCode="AU" term="%22Olde+Loohuis+LM%22">Olde Loohuis LM</searchLink>; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California Los Angeles, Los Angeles, California, USA.; Department of Computational Medicine, David Geffen School of Medicine, UCLA, Los Angeles, California, USA.; BD2: Breakthrough Discoveries for Thriving with Bipolar Disorder, Santa Monica, California, USA.; Department of Human Genetics, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, CA, USA.; Department of Psychiatry, David Geffen School of Medicine, University of California Los Angeles, Los Angeles, California, USA.
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  Data: <searchLink fieldCode="JN" term="%22101767986%22">MedRxiv : the preprint server for health sciences</searchLink> [medRxiv] 2026 Sep 27. <i>Date of Electronic Publication: </i>2026 Sep 27.
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        Value: 10.64898/2026.09.25.26363706
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        Text: English
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      – TitleFull: A founder population reveals genetic variation with major effect on serious mental illness.
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            NameFull: Gerdes G
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            NameFull: Tozzo V
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      – PersonEntity:
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            NameFull: Valencia-Echeverry J
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      – PersonEntity:
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      – PersonEntity:
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            NameFull: Arango-Restrepo C
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      – PersonEntity:
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      – PersonEntity:
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      – PersonEntity:
          Name:
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      – PersonEntity:
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      – PersonEntity:
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            NameFull: Mejía-Piedrahita JC
      – PersonEntity:
          Name:
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      – PersonEntity:
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      – PersonEntity:
          Name:
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      – PersonEntity:
          Name:
            NameFull: Pérez-Vallejo M
      – PersonEntity:
          Name:
            NameFull: Posada-Ricardo ME
      – PersonEntity:
          Name:
            NameFull: Riscanevo-Posada V
      – PersonEntity:
          Name:
            NameFull: Restrepo-Osorio C
      – PersonEntity:
          Name:
            NameFull: Restrepo-Osorio D
      – PersonEntity:
          Name:
            NameFull: Ruparel K
      – PersonEntity:
          Name:
            NameFull: Sánchez-Patiño D
      – PersonEntity:
          Name:
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      – PersonEntity:
          Name:
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      – PersonEntity:
          Name:
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      – PersonEntity:
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      – PersonEntity:
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          Name:
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          Name:
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          Name:
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      – PersonEntity:
          Name:
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      – PersonEntity:
          Name:
            NameFull: Escobar JI
      – PersonEntity:
          Name:
            NameFull: Sabatti C
      – PersonEntity:
          Name:
            NameFull: Reus VI
      – PersonEntity:
          Name:
            NameFull: Bearden CE
      – PersonEntity:
          Name:
            NameFull: Neale BM
      – PersonEntity:
          Name:
            NameFull: Lopez-Jaramillo C
      – PersonEntity:
          Name:
            NameFull: Freimer NB
      – PersonEntity:
          Name:
            NameFull: Olde Loohuis LM
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 27
              M: 09
              Text: 2026 Sep 27
              Type: published
              Y: 2026
          Titles:
            – TitleFull: MedRxiv : the preprint server for health sciences
              Type: main
ResultId 1