View in EDS HTML Full Text PDF Full Text

Loss of the tumor suppressor p53 generates a signaling gradient that drives epithelial clonal expansion.

Saved in:
Bibliographic Details
Title: Loss of the tumor suppressor p53 generates a signaling gradient that drives epithelial clonal expansion.
Authors: Gan Q; Department of Stem Cell Biology and Regenerative Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Li W; Division of Human Biology, Fred Hutchinson Cancer Center, Seattle, WA, USA., Lex RK; Division of Human Biology, Fred Hutchinson Cancer Center, Seattle, WA, USA., Ying Z; Department of Stem Cell Biology and Regenerative Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Beronja S; Division of Human Biology, Fred Hutchinson Cancer Center, Seattle, WA, USA.
Source: Science (New York, N.Y.) [Science] 2026 Oct; Vol. 394 (6819), pp. eaed3065. Date of Electronic Publication: 2026 Oct 01.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 42821692
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Loss of the tumor suppressor p53 generates a signaling gradient that drives epithelial clonal expansion.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Gan+Q%22">Gan Q</searchLink>; Department of Stem Cell Biology and Regenerative Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Li+W%22">Li W</searchLink>; Division of Human Biology, Fred Hutchinson Cancer Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Lex+RK%22">Lex RK</searchLink>; Division of Human Biology, Fred Hutchinson Cancer Center, Seattle, WA, USA.<br /><searchLink fieldCode="AU" term="%22Ying+Z%22">Ying Z</searchLink>; Department of Stem Cell Biology and Regenerative Medicine, Icahn School of Medicine at Mount Sinai, New York, NY, USA.<br /><searchLink fieldCode="AU" term="%22Beronja+S%22">Beronja S</searchLink>; Division of Human Biology, Fred Hutchinson Cancer Center, Seattle, WA, USA.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%220404511%22">Science (New York, N.Y.)</searchLink> [Science] 2026 Oct; Vol. 394 (6819), pp. eaed3065. <i>Date of Electronic Publication: </i>2026 Oct 01.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Association+for+the+Advancement+of+Science%22">American Association for the Advancement of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0404511 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1095-9203 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200368075%22">00368075 </searchLink><i>NLM ISO Abbreviation: </i>Science <i>Subsets: </i>MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=42821692
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1126/science.aed3065
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        StartPage: eaed3065
    Titles:
      – TitleFull: Loss of the tumor suppressor p53 generates a signaling gradient that drives epithelial clonal expansion.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Gan Q
      – PersonEntity:
          Name:
            NameFull: Li W
      – PersonEntity:
          Name:
            NameFull: Lex RK
      – PersonEntity:
          Name:
            NameFull: Ying Z
      – PersonEntity:
          Name:
            NameFull: Beronja S
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 10
              Text: 2026 Oct
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-electronic
              Value: 1095-9203
          Numbering:
            – Type: volume
              Value: 394
            – Type: issue
              Value: 6819
          Titles:
            – TitleFull: Science (New York, N.Y.)
              Type: main
ResultId 1