CIO-IAA is a dual ETA/ETB receptor antagonist that suppresses endothelin-1-induced macrophage activation and inflammatory signaling.
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| Title: | CIO-IAA is a dual ET |
|---|---|
| Authors: | Nguyen T; Department of Pharmaceutical Sciences, College of Pharmacy, Mercer University, Atlanta, GA, USA., Hoque N; Department of Pharmaceutical Sciences, College of Pharmacy, Mercer University, Atlanta, GA, USA; Department of Pharmacy, East West University, Dhaka, Bangladesh., Islam N; Department of Pharmaceutical Sciences, College of Pharmacy, Mercer University, Atlanta, GA, USA., Sooreni S; Department of Pharmaceutical Sciences, College of Pharmacy, Mercer University, Atlanta, GA, USA., Naser A; Department of Pharmaceutical Sciences, College of Pharmacy, Mercer University, Atlanta, GA, USA., Begum M; Department of Pharmaceutical Sciences, College of Pharmacy, Mercer University, Atlanta, GA, USA., Menon SN; Department of Pharmaceutical Sciences, College of Pharmacy, Mercer University, Atlanta, GA, USA., Jones M; Department of Pharmaceutical Sciences, College of Pharmacy, Mercer University, Atlanta, GA, USA., Ezewudo E; Department of Pharmaceutical Sciences, College of Pharmacy, Mercer University, Atlanta, GA, USA., Islam T; Caprico Biotechnologies, Duluth, GA, USA., Rubio-Alarcón M; Department of Pharmacology, University of Cambridge, Cambridge, UK., Rahman T; Department of Pharmacology, University of Cambridge, Cambridge, UK., Hasan R; Department of Pharmaceutical Sciences, College of Pharmacy, Mercer University, Atlanta, GA, USA. Electronic address: hasan_r@mercer.edu. |
| Source: | Biochemical pharmacology [Biochem Pharmacol] 2026 Oct 03; Vol. 254 (Pt 3), pp. 118517. Date of Electronic Publication: 2026 Oct 03. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Elsevier Science Country of Publication: England NLM ID: 0101032 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2968 (Electronic) Linking ISSN: 00062952 NLM ISO Abbreviation: Biochem Pharmacol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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