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Optogenetic Therapy for Restoring Aspects of Visual Function.

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Title: Optogenetic Therapy for Restoring Aspects of Visual Function.
Authors: Sahel JA; Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh.; Sorbonne Université, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, Institut de la Vision, Paris.; L'Hôpital Fondation Adolphe de Rothschild, Paris.; Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts, Paris., Futterknecht S; Institute of Molecular and Clinical Ophthalmology Basel, Basel, Switzerland.; University of Basel, Department of Ophthalmology, Basel, Switzerland., Audo I; Sorbonne Université, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, Institut de la Vision, Paris.; Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts, Paris., Martel JN; Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh., Ling S; Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh., Pagot C; Streetlab, Paris., Arleo A; Sorbonne Université, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, Institut de la Vision, Paris., Boulanger-Scemama E; L'Hôpital Fondation Adolphe de Rothschild, Paris., Duret A; Sorbonne Université, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, Institut de la Vision, Paris., de Saint Aubert JB; Sorbonne Université, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, Institut de la Vision, Paris., Delaux A; Sorbonne Université, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, Institut de la Vision, Paris., Degli Esposti S; Moorfields Eye Hospital NHS Foundation Trust, London., Coen C; Streetlab, Paris., de Montleau C; Streetlab, Paris., Aravich D; Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh., Smith W; Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh., Hayem C; Acefas, Paris., Taiel M; GenSight Biologics, Paris., Behrmann M; Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh., Roska B; Institute of Molecular and Clinical Ophthalmology Basel, Basel, Switzerland.; University of Basel, Department of Ophthalmology, Basel, Switzerland.
Source: The New England journal of medicine [N Engl J Med] 2026 Oct 08; Vol. 395 (14), pp. 1399-1408.
Publication Type: Clinical Trial, Phase I; Journal Article; Multicenter Study; Video-Audio Media
Journal Info: Publisher: Massachusetts Medical Society Country of Publication: United States NLM ID: 0255562 Publication Model: Print Cited Medium: Internet ISSN: 1533-4406 (Electronic) Linking ISSN: 00284793 NLM ISO Abbreviation: N Engl J Med Subsets: MEDLINE
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  Data: Optogenetic Therapy for Restoring Aspects of Visual Function.
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  Data: <searchLink fieldCode="AU" term="%22Sahel+JA%22">Sahel JA</searchLink>; Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh.; Sorbonne Université, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, Institut de la Vision, Paris.; L'Hôpital Fondation Adolphe de Rothschild, Paris.; Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts, Paris.<br /><searchLink fieldCode="AU" term="%22Futterknecht+S%22">Futterknecht S</searchLink>; Institute of Molecular and Clinical Ophthalmology Basel, Basel, Switzerland.; University of Basel, Department of Ophthalmology, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Audo+I%22">Audo I</searchLink>; Sorbonne Université, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, Institut de la Vision, Paris.; Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts, Paris.<br /><searchLink fieldCode="AU" term="%22Martel+JN%22">Martel JN</searchLink>; Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh.<br /><searchLink fieldCode="AU" term="%22Ling+S%22">Ling S</searchLink>; Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh.<br /><searchLink fieldCode="AU" term="%22Pagot+C%22">Pagot C</searchLink>; Streetlab, Paris.<br /><searchLink fieldCode="AU" term="%22Arleo+A%22">Arleo A</searchLink>; Sorbonne Université, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, Institut de la Vision, Paris.<br /><searchLink fieldCode="AU" term="%22Boulanger-Scemama+E%22">Boulanger-Scemama E</searchLink>; L'Hôpital Fondation Adolphe de Rothschild, Paris.<br /><searchLink fieldCode="AU" term="%22Duret+A%22">Duret A</searchLink>; Sorbonne Université, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, Institut de la Vision, Paris.<br /><searchLink fieldCode="AU" term="%22de+Saint+Aubert+JB%22">de Saint Aubert JB</searchLink>; Sorbonne Université, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, Institut de la Vision, Paris.<br /><searchLink fieldCode="AU" term="%22Delaux+A%22">Delaux A</searchLink>; Sorbonne Université, Institut National de la Santé et de la Recherche Médicale, Centre National de la Recherche Scientifique, Institut de la Vision, Paris.<br /><searchLink fieldCode="AU" term="%22Degli+Esposti+S%22">Degli Esposti S</searchLink>; Moorfields Eye Hospital NHS Foundation Trust, London.<br /><searchLink fieldCode="AU" term="%22Coen+C%22">Coen C</searchLink>; Streetlab, Paris.<br /><searchLink fieldCode="AU" term="%22de+Montleau+C%22">de Montleau C</searchLink>; Streetlab, Paris.<br /><searchLink fieldCode="AU" term="%22Aravich+D%22">Aravich D</searchLink>; Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh.<br /><searchLink fieldCode="AU" term="%22Smith+W%22">Smith W</searchLink>; Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh.<br /><searchLink fieldCode="AU" term="%22Hayem+C%22">Hayem C</searchLink>; Acefas, Paris.<br /><searchLink fieldCode="AU" term="%22Taiel+M%22">Taiel M</searchLink>; GenSight Biologics, Paris.<br /><searchLink fieldCode="AU" term="%22Behrmann+M%22">Behrmann M</searchLink>; Department of Ophthalmology, University of Pittsburgh School of Medicine, Pittsburgh.<br /><searchLink fieldCode="AU" term="%22Roska+B%22">Roska B</searchLink>; Institute of Molecular and Clinical Ophthalmology Basel, Basel, Switzerland.; University of Basel, Department of Ophthalmology, Basel, Switzerland.
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  Data: <searchLink fieldCode="JN" term="%220255562%22">The New England journal of medicine</searchLink> [N Engl J Med] 2026 Oct 08; Vol. 395 (14), pp. 1399-1408.
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