FAP adipogenesis drives early spinal muscle loss in dysferlinopathy and reveals a therapeutic target.
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| Title: | FAP adipogenesis drives early spinal muscle loss in dysferlinopathy and reveals a therapeutic target. |
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| Authors: | Moon YJ; Center for Precision Medicine and Genomics Research, Children's National Research Institute, Children's National Hospital, 7144 13th Pl NW, Washington, DC, USA.; Departments of Biochemistry and Orthopaedic Surgery, Research Institute of Clinical Medicine of Jeonbuk National University - Biomedical Research Institute of Jeonbuk National University Hospital, Jeonbuk National University Medical School, Jeonju, Republic of Korea.; Institute for Medical Science of Jeonbuk National University Medical School, Jeonju, Republic of Korea., McCormack N; Center for Precision Medicine and Genomics Research, Children's National Research Institute, Children's National Hospital, 7144 13th Pl NW, Washington, DC, USA., Diehn T; Center for Precision Medicine and Genomics Research, Children's National Research Institute, Children's National Hospital, 7144 13th Pl NW, Washington, DC, USA., Lin S; Molecular Imaging Laboratory, Department of Radiology, Howard University, Washington, DC, USA., Staedler K; Sorbonne Université, Service de Neuromyologie, Centre de référence Nord-Est-Ile-de-France, Institut de Myologie, Hôpital Pitié-Salpêtrière, 47-83 boulevard de l'Hôpital 75651 Paris Cedex 13, Paris, France.; Department of Neurology, Neurocenter of Southern Switzerland, Ente Ospedaliero Cantonale, Lugano, Switzerland., Bhattacharya S; Center for Precision Medicine and Genomics Research, Children's National Research Institute, Children's National Hospital, 7144 13th Pl NW, Washington, DC, USA., Bittel DC; Center for Precision Medicine and Genomics Research, Children's National Research Institute, Children's National Hospital, 7144 13th Pl NW, Washington, DC, USA., Wang PC; Molecular Imaging Laboratory, Department of Radiology, Howard University, Washington, DC, USA., Hogarth M; Center for Precision Medicine and Genomics Research, Children's National Research Institute, Children's National Hospital, 7144 13th Pl NW, Washington, DC, USA.; Department of Pediatrics, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA., Oh JS; Department of Orthopaedic Surgery, Jeonbuk National University Hospital, Jeonju, Republic of Korea., Goh TS; Department of Orthopaedic Surgery, Biomedical Research Institute, Pusan National University School of Medicine, Busan, Republic of Korea., Min JH; Department of Rehabilitation Medicine, Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Yangsan, Republic of Korea., Stojkovic T; Sorbonne Université, Service de Neuromyologie, Centre de référence Nord-Est-Ile-de-France, Institut de Myologie, Hôpital Pitié-Salpêtrière, 47-83 boulevard de l'Hôpital 75651 Paris Cedex 13, Paris, France., Ackermann-Bonan I; Sorbonne Université, Service de Neuromyologie, Centre de référence Nord-Est-Ile-de-France, Institut de Myologie, Hôpital Pitié-Salpêtrière, 47-83 boulevard de l'Hôpital 75651 Paris Cedex 13, Paris, France., Jaiswal JK; Center for Precision Medicine and Genomics Research, Children's National Research Institute, Children's National Hospital, 7144 13th Pl NW, Washington, DC, USA. jkjaiswal@cnmc.org.; Department of Pediatrics, The George Washington University School of Medicine and Health Sciences, Washington, DC, USA. jkjaiswal@cnmc.org. |
| Source: | EMBO molecular medicine [EMBO Mol Med] 2026 Oct; Vol. 18 (10), pp. 4034-4058. Date of Electronic Publication: 2026 Oct 12. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: EMBO Press Country of Publication: Germany NLM ID: 101487380 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1757-4684 (Electronic) Linking ISSN: 17574676 NLM ISO Abbreviation: EMBO Mol Med Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1757-4684 |
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| DOI: | 10.1038/s44321-026-00514-5 |
