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The Brain-Gut-Microbiome Axis: Exploring the Link Between Depression and Irritable Bowel Syndrome.

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Title: The Brain-Gut-Microbiome Axis: Exploring the Link Between Depression and Irritable Bowel Syndrome.
Authors: Chang L; Vatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine at UCLA, University of California, Los Angeles, California, USA; email: linchang@mednet.ucla.edu.; Goodman-Luskin Microbiome Center, Vatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine at UCLA, University of California, Los Angeles, California, USA., Freimer NB; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, California, USA.; Department of Human Genetics, University of California, Los Angeles, California, USA.; Depression Grand Challenge, University of California, Los Angeles, California, USA., Hsiao EY; Vatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine at UCLA, University of California, Los Angeles, California, USA; email: linchang@mednet.ucla.edu.; Goodman-Luskin Microbiome Center, Vatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine at UCLA, University of California, Los Angeles, California, USA.; Department of Integrative Biology and Physiology, University of California, Los Angeles, California, USA.; Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, California, USA.
Source: Annual review of physiology [Annu Rev Physiol] 2026 Oct 14. Date of Electronic Publication: 2026 Oct 14.
Publication Type: Journal Article; Review
Journal Info: Publisher: Annual Reviews Country of Publication: United States NLM ID: 0370600 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-1585 (Electronic) Linking ISSN: 00664278 NLM ISO Abbreviation: Annu Rev Physiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Chang+L%22">Chang L</searchLink>; Vatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine at UCLA, University of California, Los Angeles, California, USA; email: linchang@mednet.ucla.edu.; Goodman-Luskin Microbiome Center, Vatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine at UCLA, University of California, Los Angeles, California, USA.<br /><searchLink fieldCode="AU" term="%22Freimer+NB%22">Freimer NB</searchLink>; Center for Neurobehavioral Genetics, Semel Institute for Neuroscience and Human Behavior, University of California, Los Angeles, California, USA.; Department of Human Genetics, University of California, Los Angeles, California, USA.; Depression Grand Challenge, University of California, Los Angeles, California, USA.<br /><searchLink fieldCode="AU" term="%22Hsiao+EY%22">Hsiao EY</searchLink>; Vatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine at UCLA, University of California, Los Angeles, California, USA; email: linchang@mednet.ucla.edu.; Goodman-Luskin Microbiome Center, Vatche and Tamar Manoukian Division of Digestive Diseases, David Geffen School of Medicine at UCLA, University of California, Los Angeles, California, USA.; Department of Integrative Biology and Physiology, University of California, Los Angeles, California, USA.; Department of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, California, USA.
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        Value: 10.1146/annurev-physiol-040225-111420
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