Genotoxicity of acyl glucuronide metabolites formed from clofibric acid and gemfibrozil: a novel role for phase-II-mediated bioactivation in the hepatocarcinogenicity of the parent aglycones?

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Title: Genotoxicity of acyl glucuronide metabolites formed from clofibric acid and gemfibrozil: a novel role for phase-II-mediated bioactivation in the hepatocarcinogenicity of the parent aglycones?
Authors: Sallustio BC; Department of Clinical Pharmacology, Queen Elizabeth Hospital, Woodville, South Australia., Harkin LA, Mann MC, Krivickas SJ, Burcham PC
Source: Toxicology and applied pharmacology [Toxicol Appl Pharmacol] 1997 Dec; Vol. 147 (2), pp. 459-64.
Publication Type: Comparative Study; Journal Article
Journal Info: Publisher: Academic Press Country of Publication: United States NLM ID: 0416575 Publication Model: Print Cited Medium: Print ISSN: 0041-008X (Print) Linking ISSN: 0041008X NLM ISO Abbreviation: Toxicol Appl Pharmacol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Genotoxicity of acyl glucuronide metabolites formed from clofibric acid and gemfibrozil: a novel role for phase-II-mediated bioactivation in the hepatocarcinogenicity of the parent aglycones?
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  Data: <searchLink fieldCode="AU" term="%22Sallustio+BC%22">Sallustio BC</searchLink>; Department of Clinical Pharmacology, Queen Elizabeth Hospital, Woodville, South Australia.<br /><searchLink fieldCode="AU" term="%22Harkin+LA%22">Harkin LA</searchLink><br /><searchLink fieldCode="AU" term="%22Mann+MC%22">Mann MC</searchLink><br /><searchLink fieldCode="AU" term="%22Krivickas+SJ%22">Krivickas SJ</searchLink><br /><searchLink fieldCode="AU" term="%22Burcham+PC%22">Burcham PC</searchLink>
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  Data: <searchLink fieldCode="JN" term="%220416575%22">Toxicology and applied pharmacology</searchLink> [Toxicol Appl Pharmacol] 1997 Dec; Vol. 147 (2), pp. 459-64.
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  Data: Comparative Study; Journal Article
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Academic+Press%22">Academic Press </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>0416575 <i>Publication Model: </i>Print <i>Cited Medium: </i>Print <i>ISSN: </i>0041-008X (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%220041008X%22">0041008X </searchLink><i>NLM ISO Abbreviation: </i>Toxicol Appl Pharmacol <i>Subsets: </i>MEDLINE
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        Value: 10.1006/taap.1997.8322
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      – Code: eng
        Text: English
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        StartPage: 459
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      – TitleFull: Genotoxicity of acyl glucuronide metabolites formed from clofibric acid and gemfibrozil: a novel role for phase-II-mediated bioactivation in the hepatocarcinogenicity of the parent aglycones?
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            NameFull: Sallustio BC
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            NameFull: Harkin LA
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            NameFull: Mann MC
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            NameFull: Krivickas SJ
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            NameFull: Burcham PC
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            – D: 01
              M: 12
              Text: 1997 Dec
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              Y: 1997
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              Value: 147
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            – TitleFull: Toxicology and applied pharmacology
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