DNA Methylation: Patterns, Functions and Roles in Disease
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| Title: | DNA Methylation: Patterns, Functions and Roles in Disease |
|---|---|
| Description: | This book provides new research on the patterns, functions and roles in disease of DNA methylation. Chapter One studies the disruption of DNA methylation patterns caused by exposure to environmental factors during the developmental period. Chapter Two presents transcriptional regulation by cytosine modifications through a broad concept of molecular sciences in physics, chemistry and biology, and suggests a complex network for cytosine modifications-mediated transcription depending on multiple factors. Chapter Three reviews the loss of Insulin-like growth factor 2 (IGF2) imprinting in human tumors, focusing especially on the mechanisms underlying this abnormality in epigenetic control; and summarizes recent progress on targeting this tumor specific imprinting abnormality as a novel anti-cancer approach. |
| Authors: | Holland, Kathleen Mary |
| Resource Type: | eBook. |
| Subjects: | DNA--Methylation |
| Categories: | SCIENCE / Life Sciences / Biochemistry |
| Database: | eBook Collection (EBSCOhost) |
| FullText | Links: – Type: ebook-pdf Text: Availability: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: DNA Methylation: Patterns, Functions and Roles in Disease – Name: Abstract Label: Description Group: Ab Data: This book provides new research on the patterns, functions and roles in disease of DNA methylation. Chapter One studies the disruption of DNA methylation patterns caused by exposure to environmental factors during the developmental period. Chapter Two presents transcriptional regulation by cytosine modifications through a broad concept of molecular sciences in physics, chemistry and biology, and suggests a complex network for cytosine modifications-mediated transcription depending on multiple factors. Chapter Three reviews the loss of Insulin-like growth factor 2 (IGF2) imprinting in human tumors, focusing especially on the mechanisms underlying this abnormality in epigenetic control; and summarizes recent progress on targeting this tumor specific imprinting abnormality as a novel anti-cancer approach. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Holland%2C+Kathleen+Mary%22">Holland, Kathleen Mary</searchLink> – Name: TypePub Label: Resource Type Group: TypPub Data: eBook. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22DNA--Methylation%22">DNA--Methylation</searchLink> – Name: SubjectBISAC Label: Categories Group: Su Data: <searchLink fieldCode="ZK" term="%22SCIENCE+%2F+Life+Sciences+%2F+Biochemistry%22">SCIENCE / Life Sciences / Biochemistry</searchLink> |
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| RecordInfo | BibRecord: BibEntity: Classifications: – Code: 572.86 Scheme: ddc Type: prePub Languages: – Code: eng Text: English Subjects: – SubjectFull: DNA--Methylation Type: general Titles: – TitleFull: DNA Methylation: Patterns, Functions and Roles in Disease Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Holland, Kathleen Mary – PersonEntity: Name: NameFull: Holland, Kathleen Mary IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Type: published Y: 2016 – D: 03 M: 11 Type: profile Y: 2016 Identifiers: – Type: isbn-print Value: 9781536102444 – Type: isbn-electronic Value: 9781536102611 Titles: – TitleFull: DNA Methylation: Patterns, Functions and Roles in Disease Type: main |
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