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Statistical Methods in Genetic Epidemiology

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Title: Statistical Methods in Genetic Epidemiology
Description: This well-organized and clearly written text has a unique focus on methods of identifying the joint effects of genes and environment on disease patterns. It follows the natural sequence of research, taking readers through the study designs and statistical analysis techniques for determining whether a trait runs in families, testing hypotheses about whether a familial tendency is due to genetic or environmental factors or both, estimating the parameters of a genetic model, localizing and ultimately isolating the responsible genes, and finally characterizing their effects in the population. Examples from the literature on the genetic epidemiology of breast and colorectal cancer, among other diseases, illustrate this process. Although the book is oriented primarily towards graduate students in epidemiology, biostatistics and human genetics, it will also serve as a comprehensive reference work for researchers. Introductory chapters on molecular biology, Mendelian genetics, epidemiology, statistics, and population genetics will help make the book accessible to those coming from one of these fields without a background in the others. It strikes a good balance between epidemiologic study designs and statistical methods of data analysis.
Authors: Duncan C. Thomas
Resource Type: eBook.
Subjects: Molecular epidemiology, Genetic epidemiology--Statistical methods, Epidemiology
Categories: MEDICAL / Epidemiology, MEDICAL / Biostatistics, MEDICAL / Genetics
Database: eBook Collection (EBSCOhost)
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  Availability: 0
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PubType: eBook
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  Data: Statistical Methods in Genetic Epidemiology
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  Data: This well-organized and clearly written text has a unique focus on methods of identifying the joint effects of genes and environment on disease patterns. It follows the natural sequence of research, taking readers through the study designs and statistical analysis techniques for determining whether a trait runs in families, testing hypotheses about whether a familial tendency is due to genetic or environmental factors or both, estimating the parameters of a genetic model, localizing and ultimately isolating the responsible genes, and finally characterizing their effects in the population. Examples from the literature on the genetic epidemiology of breast and colorectal cancer, among other diseases, illustrate this process. Although the book is oriented primarily towards graduate students in epidemiology, biostatistics and human genetics, it will also serve as a comprehensive reference work for researchers. Introductory chapters on molecular biology, Mendelian genetics, epidemiology, statistics, and population genetics will help make the book accessible to those coming from one of these fields without a background in the others. It strikes a good balance between epidemiologic study designs and statistical methods of data analysis.
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  Data: <searchLink fieldCode="DE" term="%22Molecular+epidemiology%22">Molecular epidemiology</searchLink><br /><searchLink fieldCode="DE" term="%22Genetic+epidemiology--Statistical+methods%22">Genetic epidemiology--Statistical methods</searchLink><br /><searchLink fieldCode="DE" term="%22Epidemiology%22">Epidemiology</searchLink>
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      – Code: 616.042
        Scheme: ddc
        Type: prePub
    Languages:
      – Code: eng
        Text: English
    Subjects:
      – SubjectFull: Molecular epidemiology
        Type: general
      – SubjectFull: Genetic epidemiology--Statistical methods
        Type: general
      – SubjectFull: Epidemiology
        Type: general
    Titles:
      – TitleFull: Statistical Methods in Genetic Epidemiology
        Type: main
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          Name:
            NameFull: Duncan C. Thomas
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            NameFull: Duncan C. Thomas
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          Dates:
            – D: 01
              M: 01
              Type: published
              Y: 2004
            – D: 04
              M: 02
              Type: profile
              Y: 2014
          Identifiers:
            – Type: isbn-print
              Value: 9780195159394
            – Type: isbn-electronic
              Value: 9780199748051
          Titles:
            – TitleFull: Statistical Methods in Genetic Epidemiology
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