View in EDS PDF Full Text

Eye, Retina, and Visual System of the Mouse

Saved in:
Bibliographic Details
Title: Eye, Retina, and Visual System of the Mouse
Description: A comprehensive guide to current research, reflecting recent technical breakthroughs that have established the usefulness of the mouse model as part of a bilateral exchange between experimental and clinical research.Recent years have seen a burst of studies on the mouse eye and visual system, fueled in large part by the relatively recent ability to produce mice with precisely defined changes in gene sequence. Mouse models have contributed to a wide range of scientific breakthroughs for a number of ocular and neurological diseases and have allowed researchers to address fundamental issues that were difficult to approach with other experimental models. This comprehensive guide to current research captures the first wave of studies in the field, with fifty-nine chapters by leading scholars that demonstrate the usefulness of mouse models as a bridge between experimental and clinical research. The opening chapters introduce the mouse as a species and research model, discussing such topics as the mouse's evolutionary history and the mammalian visual system. Subsequent sections explore more specialized subjects, considering optics, psychophysics, and the visual behaviors of mice; the organization of the adult mouse eye and central visual system; the development of the mouse eye (including comparisons to human development); the development and plasticity of retinal projections and visuotopic maps; mouse models for human eye disease (including glaucoma and cataracts); and the application of advanced genomic technologies (including gene therapy and genetic knockouts) to the mouse visual system. Readers of this unique reference will see that the study of mouse models has already demonstrated real translational prowess in vision research.
Authors: Leo M. Chalupa, Robert W. Williams
Resource Type: eBook.
Subjects: Visual pathways, Eye, Mice--Sense organs
Categories: MEDICAL / Neuroscience, HEALTH & FITNESS / Vision
Database: eBook Collection (EBSCOhost)
FullText Links:
  – Type: ebook-pdf
Text:
  Availability: 0
Header DbId: nlebk
DbLabel: eBook Collection (EBSCOhost)
An: 235124
RelevancyScore: 1018
AccessLevel: 6
PubType: eBook
PubTypeId: ebook
PreciseRelevancyScore: 1018.08020019531
IllustrationInfo
ImageInfo – Size: thumb
  Target: https://rps2images.ebscohost.com/rpsweb/othumb?id=NL$235124$PDF&s=r
– Size: medium
  Target: https://rps2images.ebscohost.com/rpsweb/othumb?id=NL$235124$PDF&s=d
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Eye, Retina, and Visual System of the Mouse
– Name: Abstract
  Label: Description
  Group: Ab
  Data: A comprehensive guide to current research, reflecting recent technical breakthroughs that have established the usefulness of the mouse model as part of a bilateral exchange between experimental and clinical research.Recent years have seen a burst of studies on the mouse eye and visual system, fueled in large part by the relatively recent ability to produce mice with precisely defined changes in gene sequence. Mouse models have contributed to a wide range of scientific breakthroughs for a number of ocular and neurological diseases and have allowed researchers to address fundamental issues that were difficult to approach with other experimental models. This comprehensive guide to current research captures the first wave of studies in the field, with fifty-nine chapters by leading scholars that demonstrate the usefulness of mouse models as a bridge between experimental and clinical research. The opening chapters introduce the mouse as a species and research model, discussing such topics as the mouse's evolutionary history and the mammalian visual system. Subsequent sections explore more specialized subjects, considering optics, psychophysics, and the visual behaviors of mice; the organization of the adult mouse eye and central visual system; the development of the mouse eye (including comparisons to human development); the development and plasticity of retinal projections and visuotopic maps; mouse models for human eye disease (including glaucoma and cataracts); and the application of advanced genomic technologies (including gene therapy and genetic knockouts) to the mouse visual system. Readers of this unique reference will see that the study of mouse models has already demonstrated real translational prowess in vision research.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Leo+M%2E+Chalupa%22">Leo M. Chalupa</searchLink><br /><searchLink fieldCode="AR" term="%22Robert+W%2E+Williams%22">Robert W. Williams</searchLink>
– Name: TypePub
  Label: Resource Type
  Group: TypPub
  Data: eBook.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Visual+pathways%22">Visual pathways</searchLink><br /><searchLink fieldCode="DE" term="%22Eye%22">Eye</searchLink><br /><searchLink fieldCode="DE" term="%22Mice--Sense+organs%22">Mice--Sense organs</searchLink>
– Name: SubjectBISAC
  Label: Categories
  Group: Su
  Data: <searchLink fieldCode="ZK" term="%22MEDICAL+%2F+Neuroscience%22">MEDICAL / Neuroscience</searchLink><br /><searchLink fieldCode="ZK" term="%22HEALTH+%26+FITNESS+%2F+Vision%22">HEALTH & FITNESS / Vision</searchLink>
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=nlebk&AN=235124
RecordInfo BibRecord:
  BibEntity:
    Classifications:
      – Code: 573.8819353
        Scheme: ddc
        Type: prePub
    Languages:
      – Code: eng
        Text: English
    Subjects:
      – SubjectFull: Visual pathways
        Type: general
      – SubjectFull: Eye
        Type: general
      – SubjectFull: Mice--Sense organs
        Type: general
    Titles:
      – TitleFull: Eye, Retina, and Visual System of the Mouse
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Leo M. Chalupa
      – PersonEntity:
          Name:
            NameFull: Robert W. Williams
      – PersonEntity:
          Name:
            NameFull: Leo M. Chalupa
      – PersonEntity:
          Name:
            NameFull: Robert W. Williams
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 01
              Type: published
              Y: 2008
            – D: 04
              M: 02
              Type: profile
              Y: 2014
          Identifiers:
            – Type: isbn-print
              Value: 9780262033817
            – Type: isbn-electronic
              Value: 9780262270137
          Titles:
            – TitleFull: Eye, Retina, and Visual System of the Mouse
              Type: main
ResultId 1