Challenges in Endocrine Disruptor Toxicology and Risk Assessment

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Title: Challenges in Endocrine Disruptor Toxicology and Risk Assessment
Description: Insight into the role of hormones, particularly estrogen and testosterone, in health and disease etiology – including interactions with other hormone pathways – has dramatically changed. Estrogen and androgen receptors, with their polymorphisms, are key molecules in all tissues and are involved in a number of homeostatic mechanisms but also pathological processes including carcinogenesis and the development of metabolic and neurological disorders such as diabetes and Alzheimer's disease. Endocrine disrupting chemicals (EDCs) can interfere with the endocrine (hormone) systems at certain dosages and play a key role in the pathology of disease. Most known EDCs are manmade and are therefore an increasing concern given the number commonly found in household products and the environment. This book will cover the mechanisms of EDC pathology across the spectrum of disease, as well as risk assessment and government and legal regulation to provide a holistic view of the current issues and cutting-edge research in the topic. With contributions from global leaders in the field, this book will be an ideal reference for toxicologists, endocrinologists and researchers interested in developmental biology, regulatory toxicology and the interface between environment and human health.
Authors: Alberto Mantovani, Alexandra Fucic
Resource Type: eBook.
Subjects: Endocrine glands--Diseases--Pathogenesis, Endocrine toxicology, Endocrine glands--Diseases--Treatment
Categories: SCIENCE / Chemistry / Toxicology, SCIENCE / Life Sciences / Developmental Biology
Database: eBook Collection (EBSCOhost)
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  – Type: ebook-pdf
  – Type: ebook-epub
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  Availability: 0
Header DbId: nlebk
DbLabel: eBook Collection (EBSCOhost)
An: 2705686
RelevancyScore: 1103
AccessLevel: 6
PubType: eBook
PubTypeId: ebook
PreciseRelevancyScore: 1103.19409179688
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  Data: Challenges in Endocrine Disruptor Toxicology and Risk Assessment
– Name: Abstract
  Label: Description
  Group: Ab
  Data: Insight into the role of hormones, particularly estrogen and testosterone, in health and disease etiology – including interactions with other hormone pathways – has dramatically changed. Estrogen and androgen receptors, with their polymorphisms, are key molecules in all tissues and are involved in a number of homeostatic mechanisms but also pathological processes including carcinogenesis and the development of metabolic and neurological disorders such as diabetes and Alzheimer's disease. Endocrine disrupting chemicals (EDCs) can interfere with the endocrine (hormone) systems at certain dosages and play a key role in the pathology of disease. Most known EDCs are manmade and are therefore an increasing concern given the number commonly found in household products and the environment. This book will cover the mechanisms of EDC pathology across the spectrum of disease, as well as risk assessment and government and legal regulation to provide a holistic view of the current issues and cutting-edge research in the topic. With contributions from global leaders in the field, this book will be an ideal reference for toxicologists, endocrinologists and researchers interested in developmental biology, regulatory toxicology and the interface between environment and human health.
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  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Alberto+Mantovani%22">Alberto Mantovani</searchLink><br /><searchLink fieldCode="AR" term="%22Alexandra+Fucic%22">Alexandra Fucic</searchLink>
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  Data: eBook.
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  Data: <searchLink fieldCode="DE" term="%22Endocrine+glands--Diseases--Pathogenesis%22">Endocrine glands--Diseases--Pathogenesis</searchLink><br /><searchLink fieldCode="DE" term="%22Endocrine+toxicology%22">Endocrine toxicology</searchLink><br /><searchLink fieldCode="DE" term="%22Endocrine+glands--Diseases--Treatment%22">Endocrine glands--Diseases--Treatment</searchLink>
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RecordInfo BibRecord:
  BibEntity:
    Classifications:
      – Code: 616.4071
        Scheme: ddc
        Type: prePub
    Languages:
      – Code: eng
        Text: English
    Subjects:
      – SubjectFull: Endocrine glands--Diseases--Pathogenesis
        Type: general
      – SubjectFull: Endocrine toxicology
        Type: general
      – SubjectFull: Endocrine glands--Diseases--Treatment
        Type: general
    Titles:
      – TitleFull: Challenges in Endocrine Disruptor Toxicology and Risk Assessment
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Alberto Mantovani
      – PersonEntity:
          Name:
            NameFull: Alexandra Fucic
      – PersonEntity:
          Name:
            NameFull: Alberto Mantovani
      – PersonEntity:
          Name:
            NameFull: Alexandra Fucic
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 01
              Type: published
              Y: 2021
            – D: 07
              M: 01
              Type: profile
              Y: 2021
          Identifiers:
            – Type: isbn-print
              Value: 9781788017411
            – Type: isbn-electronic
              Value: 9781839160837
            – Type: isbn-electronic
              Value: 9781839160738
          Numbering:
            – Type: volume
              Value: 00042
          Titles:
            – TitleFull: Challenges in Endocrine Disruptor Toxicology and Risk Assessment
              Type: main
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