Gene Sharing and Evolution : The Diversity of Protein Functions
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| Title: | Gene Sharing and Evolution : The Diversity of Protein Functions |
|---|---|
| Description: | 'Gene sharing'means that the different functions of a protein may share the same gene--that is, a protein produced by a gene evolved to fulfill a specialized function for one biological role may also perform alternate functions for other biological roles.In the 1980s and early 1990s, Joram Piatigorsky and colleagues coined the term'gene sharing'to describe the use of multifunctional proteins as crystallins in the eye lens. In Gene Sharing and Evolution Piatigorsky explores the generality and implications of gene sharing throughout evolution and argues that most if not all proteins perform a variety of functions in the same and in different species, and that this is a fundamental necessity for evolution. How is a gene identified, by its structure or its function? Do the boundaries of a gene include its regulatory elements? What is the influence of gene expression on natural selection of protein functions, and how is variation in gene expression selected in evolution? These are neither new nor resolved questions. Piatigorsky shows us that the extensiveness of gene sharing and protein multifunctionality offers a way of responding to these questions that sheds light on the complex interrelationships among genes, proteins, and evolution. |
| Authors: | Joram Piatigorsky |
| Resource Type: | eBook. |
| Subjects: | Gene expression, Crystalline lens, Genetic regulation, Proteins--Evolution, Eye--Molecular aspects |
| Categories: | SCIENCE / Life Sciences / Molecular Biology, SCIENCE / Life Sciences / Genetics & Genomics |
| Database: | eBook Collection (EBSCOhost) |
| FullText | Links: – Type: ebook-pdf Text: Availability: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Gene Sharing and Evolution : The Diversity of Protein Functions – Name: Abstract Label: Description Group: Ab Data: 'Gene sharing'means that the different functions of a protein may share the same gene--that is, a protein produced by a gene evolved to fulfill a specialized function for one biological role may also perform alternate functions for other biological roles.In the 1980s and early 1990s, Joram Piatigorsky and colleagues coined the term'gene sharing'to describe the use of multifunctional proteins as crystallins in the eye lens. In Gene Sharing and Evolution Piatigorsky explores the generality and implications of gene sharing throughout evolution and argues that most if not all proteins perform a variety of functions in the same and in different species, and that this is a fundamental necessity for evolution. How is a gene identified, by its structure or its function? Do the boundaries of a gene include its regulatory elements? What is the influence of gene expression on natural selection of protein functions, and how is variation in gene expression selected in evolution? These are neither new nor resolved questions. Piatigorsky shows us that the extensiveness of gene sharing and protein multifunctionality offers a way of responding to these questions that sheds light on the complex interrelationships among genes, proteins, and evolution. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Joram+Piatigorsky%22">Joram Piatigorsky</searchLink> – Name: TypePub Label: Resource Type Group: TypPub Data: eBook. – Name: Subject Label: Subjects Group: Su Data: <searchLink fieldCode="DE" term="%22Gene+expression%22">Gene expression</searchLink><br /><searchLink fieldCode="DE" term="%22Crystalline+lens%22">Crystalline lens</searchLink><br /><searchLink fieldCode="DE" term="%22Genetic+regulation%22">Genetic regulation</searchLink><br /><searchLink fieldCode="DE" term="%22Proteins--Evolution%22">Proteins--Evolution</searchLink><br /><searchLink fieldCode="DE" term="%22Eye--Molecular+aspects%22">Eye--Molecular aspects</searchLink> – Name: SubjectBISAC Label: Categories Group: Su Data: <searchLink fieldCode="ZK" term="%22SCIENCE+%2F+Life+Sciences+%2F+Molecular+Biology%22">SCIENCE / Life Sciences / Molecular Biology</searchLink><br /><searchLink fieldCode="ZK" term="%22SCIENCE+%2F+Life+Sciences+%2F+Genetics+%26+Genomics%22">SCIENCE / Life Sciences / Genetics & Genomics</searchLink> |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=nlebk&AN=282328 |
| RecordInfo | BibRecord: BibEntity: Classifications: – Code: 572.6 Scheme: ddc Type: prePub Languages: – Code: eng Text: English Subjects: – SubjectFull: Gene expression Type: general – SubjectFull: Crystalline lens Type: general – SubjectFull: Genetic regulation Type: general – SubjectFull: Proteins--Evolution Type: general – SubjectFull: Eye--Molecular aspects Type: general Titles: – TitleFull: Gene Sharing and Evolution : The Diversity of Protein Functions Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Joram Piatigorsky – PersonEntity: Name: NameFull: Joram Piatigorsky IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 01 Type: published Y: 2007 – D: 04 M: 02 Type: profile Y: 2014 Identifiers: – Type: isbn-print Value: 9780674023413 – Type: isbn-electronic Value: 9780674042124 Titles: – TitleFull: Gene Sharing and Evolution : The Diversity of Protein Functions Type: main |
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