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Epigenetics: Mechanisms, Functions and Human Effects

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Title: Epigenetics: Mechanisms, Functions and Human Effects
Description: Epigenetics refers to DNA and chromatin modifications that persist from one cell division to the next despite a lack of change in the underlying DNA sequence. It is an emergent field since its implication in physiological and disease processes is now widely accepted. The effects of epigenetics play an important role in development but can also arise stochastically with aging. Since their discovery in 1983, cancer-associated epigenetic changes have become accepted as playing a pivotal role in carcinogenesis, in conjunction with classical genomic mutations. Thus it is now well established that an epigenetic mechanism underlies the pathogenesis of cancer and there is evidence implicating epigenetic factors in the pathogenesis of idiopathic mental disorders such as schizophrenia, bipolar disorder and even autism. This new book gathers the latest research from around the globe in this field of study and related topics.
Authors: Balázs Pintér
Resource Type: eBook.
Subjects: Cancer--Etiology, Cancer--Genetic aspects, Epigenesis
Categories: SCIENCE / Life Sciences / Genetics & Genomics
Database: eBook Collection (EBSCOhost)
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  – Type: ebook-pdf
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  Availability: 0
Header DbId: nlebk
DbLabel: eBook Collection (EBSCOhost)
An: 347497
RelevancyScore: 1031
AccessLevel: 6
PubType: eBook
PubTypeId: ebook
PreciseRelevancyScore: 1031.17456054688
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  Label: Title
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  Data: Epigenetics: Mechanisms, Functions and Human Effects
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  Label: Description
  Group: Ab
  Data: Epigenetics refers to DNA and chromatin modifications that persist from one cell division to the next despite a lack of change in the underlying DNA sequence. It is an emergent field since its implication in physiological and disease processes is now widely accepted. The effects of epigenetics play an important role in development but can also arise stochastically with aging. Since their discovery in 1983, cancer-associated epigenetic changes have become accepted as playing a pivotal role in carcinogenesis, in conjunction with classical genomic mutations. Thus it is now well established that an epigenetic mechanism underlies the pathogenesis of cancer and there is evidence implicating epigenetic factors in the pathogenesis of idiopathic mental disorders such as schizophrenia, bipolar disorder and even autism. This new book gathers the latest research from around the globe in this field of study and related topics.
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  Data: <searchLink fieldCode="AR" term="%22Balázs+Pintér%22">Balázs Pintér</searchLink>
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  Data: <searchLink fieldCode="DE" term="%22Cancer--Etiology%22">Cancer--Etiology</searchLink><br /><searchLink fieldCode="DE" term="%22Cancer--Genetic+aspects%22">Cancer--Genetic aspects</searchLink><br /><searchLink fieldCode="DE" term="%22Epigenesis%22">Epigenesis</searchLink>
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RecordInfo BibRecord:
  BibEntity:
    Classifications:
      – Code: 616.994042
        Scheme: ddc
        Type: prePub
    Languages:
      – Code: eng
        Text: English
    Subjects:
      – SubjectFull: Cancer--Etiology
        Type: general
      – SubjectFull: Cancer--Genetic aspects
        Type: general
      – SubjectFull: Epigenesis
        Type: general
    Titles:
      – TitleFull: Epigenetics: Mechanisms, Functions and Human Effects
        Type: main
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      – PersonEntity:
          Name:
            NameFull: Balázs Pintér
      – PersonEntity:
          Name:
            NameFull: Balázs Pintér
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      – BibEntity:
          Dates:
            – D: 01
              M: 01
              Type: published
              Y: 2010
            – D: 04
              M: 02
              Type: profile
              Y: 2014
          Identifiers:
            – Type: isbn-print
              Value: 9781607414544
            – Type: isbn-electronic
              Value: 9781616688738
          Titles:
            – TitleFull: Epigenetics: Mechanisms, Functions and Human Effects
              Type: main
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