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Establishment of Cancer Gene Therapy

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Title: Establishment of Cancer Gene Therapy
Description: This book describes a 40-year research battle against cancer and, more specifically, glioblastoma, one of the most fatal brain tumours. Using different immunological strategies to fight this disease, the author was able to finally establish a revolutionary and successful treatment based principally on molecular biology named Cancer Gene Therapy. Although this cancer immuno-gene therapy was proposed as an experimental technique back in 1993, clinical results were not fully demonstrated until the 2005-2020s. This therapy can be summarized as follows: after arrest in cancer cells of the principal cancer growth factor IGF-I, using anti-gene IGF-I technology (antisense and triple helix), cells become immunogenic vaccines. Vaccination of glioblastoma patients induces an immune anti-tumour response, allowing an increase in median survival up to two years and a better quality of life.
Authors: Jerzy Trojan, Author
Resource Type: eBook.
Subjects: Cancer--Gene therapy--History
Categories: MEDICAL / Oncology / General, MEDICAL / Chemotherapy, MEDICAL / History
Database: eBook Collection (EBSCOhost)
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  – Type: ebook-pdf
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  Availability: 0
Header DbId: nlebk
DbLabel: eBook Collection (EBSCOhost)
An: 3570785
RelevancyScore: 1116
AccessLevel: 6
PubType: eBook
PubTypeId: ebook
PreciseRelevancyScore: 1116.28857421875
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  Data: Establishment of Cancer Gene Therapy
– Name: Abstract
  Label: Description
  Group: Ab
  Data: This book describes a 40-year research battle against cancer and, more specifically, glioblastoma, one of the most fatal brain tumours. Using different immunological strategies to fight this disease, the author was able to finally establish a revolutionary and successful treatment based principally on molecular biology named Cancer Gene Therapy. Although this cancer immuno-gene therapy was proposed as an experimental technique back in 1993, clinical results were not fully demonstrated until the 2005-2020s. This therapy can be summarized as follows: after arrest in cancer cells of the principal cancer growth factor IGF-I, using anti-gene IGF-I technology (antisense and triple helix), cells become immunogenic vaccines. Vaccination of glioblastoma patients induces an immune anti-tumour response, allowing an increase in median survival up to two years and a better quality of life.
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RecordInfo BibRecord:
  BibEntity:
    Classifications:
      – Code: 616.994042
        Scheme: ddc
        Type: prePub
    Languages:
      – Code: eng
        Text: English
    Subjects:
      – SubjectFull: Cancer--Gene therapy--History
        Type: general
    Titles:
      – TitleFull: Establishment of Cancer Gene Therapy
        Type: main
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      – PersonEntity:
          Name:
            NameFull: Jerzy Trojan, Author
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          Name:
            NameFull: Jerzy Trojan, Author
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          Dates:
            – D: 01
              M: 01
              Type: published
              Y: 2023
            – D: 18
              M: 05
              Type: profile
              Y: 2023
          Identifiers:
            – Type: isbn-print
              Value: 9781527593893
            – Type: isbn-electronic
              Value: 9781527593909
          Titles:
            – TitleFull: Establishment of Cancer Gene Therapy
              Type: main
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