Biophysics of Molecular Chaperones : Function, Mechanisms and Client Protein Interactions

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Title: Biophysics of Molecular Chaperones : Function, Mechanisms and Client Protein Interactions
Description: Molecular chaperones are critical to control protein quality in all living cells. Understanding chaperone function at the atomic level, and in particular its mode of interaction with client proteins, is crucial to understanding the fundamental roles chaperones play in biology. This book fills a gap in the literature by comprehensively summarizing and discussing new advanced experimental techniques for their analysis. Providing a comprehensive overview of advanced biophysical methods for the characterization of molecular mechanisms of molecular chaperones, the majority of the contributions are NMR methodology. This is the method of choice for atomic resolution studies of such systems. Additional notable biophysical approaches are considered to present all relevant current developments in exploring chaperone function and the transient and dynamic interactions with their client proteins. The book is targeted at both current practitioners of structural biology and biophysical chemistry and scientists who are interested in entering the field. It could be useful for graduate students as supplementary reading.
Authors: Sebastian Hiller, Maili Liu, Lichun He
Resource Type: eBook.
Subjects: Biophysics, Molecular chaperones
Categories: SCIENCE / Physics / General, SCIENCE / Chemistry / Analytic, SCIENCE / Life Sciences / Molecular Biology
Database: eBook Collection (EBSCOhost)
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  – Type: ebook-pdf
  – Type: ebook-epub
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  Availability: 0
Header DbId: nlebk
DbLabel: eBook Collection (EBSCOhost)
An: 3717248
RelevancyScore: 1123
AccessLevel: 6
PubType: eBook
PubTypeId: ebook
PreciseRelevancyScore: 1122.83581542969
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  Label: Title
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  Data: Biophysics of Molecular Chaperones : Function, Mechanisms and Client Protein Interactions
– Name: Abstract
  Label: Description
  Group: Ab
  Data: Molecular chaperones are critical to control protein quality in all living cells. Understanding chaperone function at the atomic level, and in particular its mode of interaction with client proteins, is crucial to understanding the fundamental roles chaperones play in biology. This book fills a gap in the literature by comprehensively summarizing and discussing new advanced experimental techniques for their analysis. Providing a comprehensive overview of advanced biophysical methods for the characterization of molecular mechanisms of molecular chaperones, the majority of the contributions are NMR methodology. This is the method of choice for atomic resolution studies of such systems. Additional notable biophysical approaches are considered to present all relevant current developments in exploring chaperone function and the transient and dynamic interactions with their client proteins. The book is targeted at both current practitioners of structural biology and biophysical chemistry and scientists who are interested in entering the field. It could be useful for graduate students as supplementary reading.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Sebastian+Hiller%22">Sebastian Hiller</searchLink><br /><searchLink fieldCode="AR" term="%22Maili+Liu%22">Maili Liu</searchLink><br /><searchLink fieldCode="AR" term="%22Lichun+He%22">Lichun He</searchLink>
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  Data: eBook.
– Name: Subject
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  Data: <searchLink fieldCode="DE" term="%22Biophysics%22">Biophysics</searchLink><br /><searchLink fieldCode="DE" term="%22Molecular+chaperones%22">Molecular chaperones</searchLink>
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RecordInfo BibRecord:
  BibEntity:
    Classifications:
      – Code: 572.633
        Scheme: ddc
        Type: prePub
    Languages:
      – Code: eng
        Text: English
    Subjects:
      – SubjectFull: Biophysics
        Type: general
      – SubjectFull: Molecular chaperones
        Type: general
    Titles:
      – TitleFull: Biophysics of Molecular Chaperones : Function, Mechanisms and Client Protein Interactions
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Sebastian Hiller
      – PersonEntity:
          Name:
            NameFull: Maili Liu
      – PersonEntity:
          Name:
            NameFull: Lichun He
      – PersonEntity:
          Name:
            NameFull: Sebastian Hiller
      – PersonEntity:
          Name:
            NameFull: Maili Liu
      – PersonEntity:
          Name:
            NameFull: Lichun He
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      – BibEntity:
          Dates:
            – D: 01
              M: 01
              Type: published
              Y: 2024
            – D: 01
              M: 12
              Type: profile
              Y: 2023
          Identifiers:
            – Type: isbn-print
              Value: 9781839162824
            – Type: isbn-electronic
              Value: 9781839165993
          Numbering:
            – Type: volume
              Value: 00029
          Titles:
            – TitleFull: Biophysics of Molecular Chaperones : Function, Mechanisms and Client Protein Interactions
              Type: main
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