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Male-mediated Developmental Toxicity

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Title: Male-mediated Developmental Toxicity
Description: Germ cells have a unique and critical role as the conduit for hereditary information. The issue of male germline mutagenesis and the effects on developmental defects in the next generation has become increasingly high profile in recent years. Understanding the mechanisms by which the germline is induced and maintained is one of the effective ways to treat infertility and cancer. Male-mediated Developmental Toxicity discusses these issues and provides analysis of the fundamental mechanisms of mutations covering both clinical and experimental aspects. It helps clarify the data explaining how genotoxicity involves multiple modes of action and highlights novel models and assays being used to assess germ cell genotoxicity. With a clear focus on the various mechanisms that could impact human health, this book is for postgraduate students and researchers in reproductive and developmental toxicology as well as those with an interest in the fields of genetically inherited diseases, developmental biology and, potentially, those with a more clinical background.
Authors: Diana Anderson, Khaled Habas
Resource Type: eBook.
Subjects: Spermatogenesis, Antibody diversity, Mutagenesis
Categories: MEDICAL / Toxicology, SCIENCE / Chemistry / Clinical
Database: eBook Collection (EBSCOhost)
FullText Links:
  – Type: ebook-epub
Text:
  Availability: 0
Header DbId: nlebk
DbLabel: eBook Collection (EBSCOhost)
An: 3848745
RelevancyScore: 1123
AccessLevel: 6
PubType: eBook
PubTypeId: ebook
PreciseRelevancyScore: 1122.83581542969
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Items – Name: Title
  Label: Title
  Group: Ti
  Data: Male-mediated Developmental Toxicity
– Name: Abstract
  Label: Description
  Group: Ab
  Data: Germ cells have a unique and critical role as the conduit for hereditary information. The issue of male germline mutagenesis and the effects on developmental defects in the next generation has become increasingly high profile in recent years. Understanding the mechanisms by which the germline is induced and maintained is one of the effective ways to treat infertility and cancer. Male-mediated Developmental Toxicity discusses these issues and provides analysis of the fundamental mechanisms of mutations covering both clinical and experimental aspects. It helps clarify the data explaining how genotoxicity involves multiple modes of action and highlights novel models and assays being used to assess germ cell genotoxicity. With a clear focus on the various mechanisms that could impact human health, this book is for postgraduate students and researchers in reproductive and developmental toxicology as well as those with an interest in the fields of genetically inherited diseases, developmental biology and, potentially, those with a more clinical background.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Diana+Anderson%22">Diana Anderson</searchLink><br /><searchLink fieldCode="AR" term="%22Khaled+Habas%22">Khaled Habas</searchLink>
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  Data: eBook.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Spermatogenesis%22">Spermatogenesis</searchLink><br /><searchLink fieldCode="DE" term="%22Antibody+diversity%22">Antibody diversity</searchLink><br /><searchLink fieldCode="DE" term="%22Mutagenesis%22">Mutagenesis</searchLink>
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  Data: <searchLink fieldCode="ZK" term="%22MEDICAL+%2F+Toxicology%22">MEDICAL / Toxicology</searchLink><br /><searchLink fieldCode="ZK" term="%22SCIENCE+%2F+Chemistry+%2F+Clinical%22">SCIENCE / Chemistry / Clinical</searchLink>
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RecordInfo BibRecord:
  BibEntity:
    Classifications:
      – Code: 572.838
        Scheme: ddc
        Type: prePub
    Languages:
      – Code: eng
        Text: English
    Subjects:
      – SubjectFull: Spermatogenesis
        Type: general
      – SubjectFull: Antibody diversity
        Type: general
      – SubjectFull: Mutagenesis
        Type: general
    Titles:
      – TitleFull: Male-mediated Developmental Toxicity
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Diana Anderson
      – PersonEntity:
          Name:
            NameFull: Khaled Habas
      – PersonEntity:
          Name:
            NameFull: Diana Anderson
      – PersonEntity:
          Name:
            NameFull: Khaled Habas
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 01
              Type: published
              Y: 2024
            – D: 11
              M: 12
              Type: profile
              Y: 2025
          Identifiers:
            – Type: isbn-print
              Value: 9781839167195
            – Type: isbn-electronic
              Value: 9781837670208
          Titles:
            – TitleFull: Male-mediated Developmental Toxicity
              Type: main
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