Mortality associated with benzodiazepines and benzodiazepine-related drugs among community-dwelling older people in Finland: a population-based retrospective cohort study.
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| Title: | Mortality associated with benzodiazepines and benzodiazepine-related drugs among community-dwelling older people in Finland: a population-based retrospective cohort study. |
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| Authors: | Gisev N (AUTHOR), Hartikainen S (AUTHOR), Chen TF (AUTHOR), Korhonen M (AUTHOR), Bell JS (AUTHOR), Gisev, Natasa (AUTHOR), Hartikainen, Sirpa (AUTHOR), Chen, Timothy F (AUTHOR), Korhonen, Mikko (AUTHOR), Bell, J Simon (AUTHOR) |
| Source: | Canadian Journal of Psychiatry. Jun2011, Vol. 56 Issue 6, p377-381. 5p. |
| Abstract: | |
| Copyright of Canadian Journal of Psychiatry is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 104573766 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Mortality associated with benzodiazepines and benzodiazepine-related drugs among community-dwelling older people in Finland: a population-based retrospective cohort study. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Gisev+N%22">Gisev N</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hartikainen+S%22">Hartikainen S</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Chen+TF%22">Chen TF</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Korhonen+M%22">Korhonen M</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Bell+JS%22">Bell JS</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Gisev%2C+Natasa%22">Gisev, Natasa</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hartikainen%2C+Sirpa%22">Hartikainen, Sirpa</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Chen%2C+Timothy+F%22">Chen, Timothy F</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Korhonen%2C+Mikko%22">Korhonen, Mikko</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Bell%2C+J+Simon%22">Bell, J Simon</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Canadian+Journal+of+Psychiatry%22">Canadian Journal of Psychiatry</searchLink>. Jun2011, Vol. 56 Issue 6, p377-381. 5p. – Name: Abstract Label: Abstract Group: Ab Data: <bold>Objective: </bold>To investigate the association between the use of benzodiazepines (BDZs) and BDZ-related drugs and mortality among community-dwelling people aged 65 years and older in Finland.<bold>Method: </bold>This was a population-based retrospective cohort study. Records of all reimbursed drugs purchased by all 2224 residents of Leppävirta, Finland, aged 65 years and older in 2000 were extracted from the Finnish National Prescription Register. Diagnostic data were extracted from the Special Reimbursement Register. All-cause mortality was assessed after 9 years using national registers. Cox proportional hazards models were used to compute unadjusted and adjusted hazard ratios (HRs) and 95% confidence intervals for mortality among prevalent users of BDZs and BDZ-related drugs in 2000 (n = 325), compared with nonusers of BDZs and BDZ-related drugs between 2000 and 2008 (n = 1520).<bold>Results: </bold>BDZs and BDZ-related drugs were used by 325 out of the 2224 residents (14.6%) in 2000. The 9-year mortality was 50.2% among BDZ and BDZ-related drug users in 2000 and 36.3% among BDZ and BDZ-related drug nonusers between 2000 and 2008 (HR 1.53; 95% CI 1.28 to 1.82). After adjusting for baseline age, sex, antipsychotic drug use, and diagnostic confounders, the HR was 1.01 (95% CI 0.84 to 1.21).<bold>Conclusions: </bold>Use of BDZs and BDZ-related drugs was associated with an increased mortality hazard in unadjusted analyses. However, after adjusting for age, sex, antipsychotic drug use, and diagnostic confounders, the use of BDZs and BDZ-related drugs was not associated with excess mortality. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Canadian Journal of Psychiatry is the property of Sage Publications Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 5 StartPage: 377 Titles: – TitleFull: Mortality associated with benzodiazepines and benzodiazepine-related drugs among community-dwelling older people in Finland: a population-based retrospective cohort study. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Gisev N – PersonEntity: Name: NameFull: Hartikainen S – PersonEntity: Name: NameFull: Chen TF – PersonEntity: Name: NameFull: Korhonen M – PersonEntity: Name: NameFull: Bell JS – PersonEntity: Name: NameFull: Gisev, Natasa – PersonEntity: Name: NameFull: Hartikainen, Sirpa – PersonEntity: Name: NameFull: Chen, Timothy F – PersonEntity: Name: NameFull: Korhonen, Mikko – PersonEntity: Name: NameFull: Bell, J Simon IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 06 Text: Jun2011 Type: published Y: 2011 Identifiers: – Type: issn-print Value: 07067437 Numbering: – Type: volume Value: 56 – Type: issue Value: 6 Titles: – TitleFull: Canadian Journal of Psychiatry Type: main |
| ResultId | 1 |
