Childhood adversities and adult psychopathology in the National Comorbidity Survey Replication (NCS-R) III: associations with functional impairment related to DSM-IV disorders.
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| Title: | Childhood adversities and adult psychopathology in the National Comorbidity Survey Replication (NCS-R) III: associations with functional impairment related to DSM-IV disorders. |
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| Authors: | McLaughlin KA (AUTHOR), Green JG (AUTHOR), Gruber MJ (AUTHOR), Sampson NA (AUTHOR), Zaslavsky AM (AUTHOR), Kessler RC (AUTHOR) |
| Source: | Psychological Medicine. May2010, Vol. 40 Issue 5, p847-859. 13p. |
| Abstract: | BACKGROUND: Despite evidence that childhood adversities (CAs) are associated with increased risk of mental disorders, little is known about their associations with disorder-related impairment. We report the associations between CAs and functional impairment associated with 12-month DSM-IV disorders in a national sample. METHOD: We used data from the US National Comorbidity Survey Replication (NCS-R). Respondents completed diagnostic interviews that assessed 12-month DSM-IV disorder prevalence and impairment. Associations of 12 retrospectively reported CAs with impairment among cases (n=2242) were assessed using multiple regression analysis. Impairment measures included a dichotomous measure of classification in the severe range of impairment on the Sheehan Disability Scale (SDS) and a measure of self-reported number of days out of role due to emotional problems in the past 12 months. RESULTS: CAs were positively and significantly associated with impairment. Predictive effects of CAs on the SDS were particularly pronounced for anxiety disorders and were significant in predicting increased days out of role associated with mood, anxiety and disruptive behavior disorders. Predictive effects persisted throughout the life course and were not accounted for by disorder co-morbidity. CAs associated with maladaptive family functioning (MFF; parental mental illness, substance disorder, criminality, family violence, abuse, neglect) were more consistently associated with impairment than other CAs. The joint effects of co-morbid MFF CAs were significantly subadditive. Simulations suggest that CAs account for 19.6% of severely impairing disorders and 17.4% of days out of role. CONCLUSIONS: CAs predict greater disorder-related impairment, highlighting the ongoing clinical significance of CAs at every stage of the life course. [ABSTRACT FROM AUTHOR] |
| Copyright of Psychological Medicine is the property of Cambridge University Press and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 105191003 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Childhood adversities and adult psychopathology in the National Comorbidity Survey Replication (NCS-R) III: associations with functional impairment related to DSM-IV disorders. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22McLaughlin+KA%22">McLaughlin KA</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Green+JG%22">Green JG</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Gruber+MJ%22">Gruber MJ</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Sampson+NA%22">Sampson NA</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Zaslavsky+AM%22">Zaslavsky AM</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kessler+RC%22">Kessler RC</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Psychological+Medicine%22">Psychological Medicine</searchLink>. May2010, Vol. 40 Issue 5, p847-859. 13p. – Name: Abstract Label: Abstract Group: Ab Data: BACKGROUND: Despite evidence that childhood adversities (CAs) are associated with increased risk of mental disorders, little is known about their associations with disorder-related impairment. We report the associations between CAs and functional impairment associated with 12-month DSM-IV disorders in a national sample. METHOD: We used data from the US National Comorbidity Survey Replication (NCS-R). Respondents completed diagnostic interviews that assessed 12-month DSM-IV disorder prevalence and impairment. Associations of 12 retrospectively reported CAs with impairment among cases (n=2242) were assessed using multiple regression analysis. Impairment measures included a dichotomous measure of classification in the severe range of impairment on the Sheehan Disability Scale (SDS) and a measure of self-reported number of days out of role due to emotional problems in the past 12 months. RESULTS: CAs were positively and significantly associated with impairment. Predictive effects of CAs on the SDS were particularly pronounced for anxiety disorders and were significant in predicting increased days out of role associated with mood, anxiety and disruptive behavior disorders. Predictive effects persisted throughout the life course and were not accounted for by disorder co-morbidity. CAs associated with maladaptive family functioning (MFF; parental mental illness, substance disorder, criminality, family violence, abuse, neglect) were more consistently associated with impairment than other CAs. The joint effects of co-morbid MFF CAs were significantly subadditive. Simulations suggest that CAs account for 19.6% of severely impairing disorders and 17.4% of days out of role. CONCLUSIONS: CAs predict greater disorder-related impairment, highlighting the ongoing clinical significance of CAs at every stage of the life course. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Psychological Medicine is the property of Cambridge University Press and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=105191003 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1017/s0033291709991115 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 13 StartPage: 847 Titles: – TitleFull: Childhood adversities and adult psychopathology in the National Comorbidity Survey Replication (NCS-R) III: associations with functional impairment related to DSM-IV disorders. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: McLaughlin KA – PersonEntity: Name: NameFull: Green JG – PersonEntity: Name: NameFull: Gruber MJ – PersonEntity: Name: NameFull: Sampson NA – PersonEntity: Name: NameFull: Zaslavsky AM – PersonEntity: Name: NameFull: Kessler RC IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 05 Text: May2010 Type: published Y: 2010 Identifiers: – Type: issn-print Value: 00332917 Numbering: – Type: volume Value: 40 – Type: issue Value: 5 Titles: – TitleFull: Psychological Medicine Type: main |
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