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Lifetime comorbidities between phobic disorders and major depression in Japan: results from the World Mental Health Japan 2002-2004 Survey.

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Title: Lifetime comorbidities between phobic disorders and major depression in Japan: results from the World Mental Health Japan 2002-2004 Survey.
Authors: Tsuchiya M (AUTHOR), Kawakami N (AUTHOR), Ono Y (AUTHOR), Nakane Y (AUTHOR), Nakamura Y (AUTHOR), Tachimori H (AUTHOR), Iwata N (AUTHOR), Uda H (AUTHOR), Nakane H (AUTHOR), Watanabe M (AUTHOR), Naganuma Y (AUTHOR), Furukawa TA (AUTHOR), Hata Y (AUTHOR), Kobayashi M (AUTHOR), Miyake Y (AUTHOR), Takeshima T (AUTHOR), Kikkawa T (AUTHOR), Kessler RC (AUTHOR), Tsuchiya, Masao (AUTHOR), Kawakami, Norito (AUTHOR)
Source: Depression & Anxiety (1091-4269). Oct2009, Vol. 26 Issue 10, p949-955. 7p.
Abstract: Background: Although often considered of minor significance in themselves, evidence exists that early-onset phobic disorders might be predictors of later more serious disorders, such as major depressive disorder (MDD). The purpose of this study is to investigate the association of phobic disorders with the onset of MDD in the community in Japan.Methods: Data from the World Mental Health Japan 2002-2004 Survey were analyzed. A total of 2,436 community residents aged 20 and older were interviewed using the WHO Composite International Diagnostic Interview 3.0 (response rate, 58.4%). A Cox proportional hazard model was used to predict the onset of MDD as a function of prior history of DSM-IV specific phobia, agoraphobia, or social phobia, adjusting for gender, birth-cohort, other anxiety disorders, education, and marital status at survey.Results: Social phobia was strongly associated with the subsequent onset of MDD (hazard ratio [HR]=4.1 [95% CI: 2.0-8.7]) after adjusting for sex, birth cohort, and the number of other anxiety disorders. The association between agoraphobia or specific phobia and MDD was not statistically significant after adjusting for these variables.Conclusions: Social phobia is a powerful predictor of the subsequent first onset of MDD in Japan. Although this finding argues against a simple neurobiological model and in favor of a model in which the cultural meanings of phobia play a part in promoting MDD, an elucidation of causal pathways will require more fine-grained comparative research. [ABSTRACT FROM AUTHOR]
Copyright of Depression & Anxiety (1091-4269) is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
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  Data: Lifetime comorbidities between phobic disorders and major depression in Japan: results from the World Mental Health Japan 2002-2004 Survey.
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  Data: <searchLink fieldCode="AR" term="%22Tsuchiya+M%22">Tsuchiya M</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kawakami+N%22">Kawakami N</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Ono+Y%22">Ono Y</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Nakane+Y%22">Nakane Y</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Nakamura+Y%22">Nakamura Y</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Tachimori+H%22">Tachimori H</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Iwata+N%22">Iwata N</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Uda+H%22">Uda H</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Nakane+H%22">Nakane H</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Watanabe+M%22">Watanabe M</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Naganuma+Y%22">Naganuma Y</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Furukawa+TA%22">Furukawa TA</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hata+Y%22">Hata Y</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kobayashi+M%22">Kobayashi M</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Miyake+Y%22">Miyake Y</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Takeshima+T%22">Takeshima T</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kikkawa+T%22">Kikkawa T</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kessler+RC%22">Kessler RC</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Tsuchiya%2C+Masao%22">Tsuchiya, Masao</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Kawakami%2C+Norito%22">Kawakami, Norito</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Depression+%26+Anxiety+%281091-4269%29%22">Depression & Anxiety (1091-4269)</searchLink>. Oct2009, Vol. 26 Issue 10, p949-955. 7p.
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: <bold>Background: </bold>Although often considered of minor significance in themselves, evidence exists that early-onset phobic disorders might be predictors of later more serious disorders, such as major depressive disorder (MDD). The purpose of this study is to investigate the association of phobic disorders with the onset of MDD in the community in Japan.<bold>Methods: </bold>Data from the World Mental Health Japan 2002-2004 Survey were analyzed. A total of 2,436 community residents aged 20 and older were interviewed using the WHO Composite International Diagnostic Interview 3.0 (response rate, 58.4%). A Cox proportional hazard model was used to predict the onset of MDD as a function of prior history of DSM-IV specific phobia, agoraphobia, or social phobia, adjusting for gender, birth-cohort, other anxiety disorders, education, and marital status at survey.<bold>Results: </bold>Social phobia was strongly associated with the subsequent onset of MDD (hazard ratio [HR]=4.1 [95% CI: 2.0-8.7]) after adjusting for sex, birth cohort, and the number of other anxiety disorders. The association between agoraphobia or specific phobia and MDD was not statistically significant after adjusting for these variables.<bold>Conclusions: </bold>Social phobia is a powerful predictor of the subsequent first onset of MDD in Japan. Although this finding argues against a simple neurobiological model and in favor of a model in which the cultural meanings of phobia play a part in promoting MDD, an elucidation of causal pathways will require more fine-grained comparative research. [ABSTRACT FROM AUTHOR]
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  Label:
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  Data: <i>Copyright of Depression & Anxiety (1091-4269) is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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