View in EDS PDF Full Text

Distal myasthenia gravis – frequency and clinical course in a large prospective series.

Saved in:
Bibliographic Details
Title: Distal myasthenia gravis – frequency and clinical course in a large prospective series.
Authors: Werner, P., Kiechl, S., Löscher, W., Poewe, W., Willeit, J.
Source: Acta Neurologica Scandinavica. Sep2003, Vol. 108 Issue 3, p209-211. 3p.
Subjects: Myasthenia gravis, Neuromuscular diseases, Neurological disorders, Muscle diseases
Abstract: Objectives – In Myasthenia gravis (MG) proximal limb, ocular and/or bulbar muscles are most commonly affected, whereas distal extremity muscles are typically spared. The aim of the current study was to assess the frequency of primarily distal MG in the Tyrol and to describe its clinical peculiarities. Material and methods – Over the past 20 years 84 patients with MG have undergone follow-up at the Department of Neurology of Innsbruck University. Types of presentation, clinical course and treatment response were followed over a period of 20 years (1980–2000). Results – Six of 84 MG patients showed a predominance of muscle weakness and fatigability in distal limb muscles (two at presentation, four over the later course of the illness). There was no difference between distal MG and MG with a more typical distribution of muscle weakness regarding age, gender and response to therapy. Conclusions – The case series indicates that predominantly distal presentations of otherwise typical MG are more frequent than generally assumed and should be considered in the differential diagnosis of diseases with distal limb weakness. [ABSTRACT FROM AUTHOR]
Copyright of Acta Neurologica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
FullText Links:
  – Type: pdflink
Text:
  Availability: 0
Header DbId: pbh
DbLabel: Psychology and Behavioral Sciences Collection
An: 10531445
AccessLevel: 6
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: Distal myasthenia gravis – frequency and clinical course in a large prospective series.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AR" term="%22Werner%2C+P%2E%22">Werner, P.</searchLink><br /><searchLink fieldCode="AR" term="%22Kiechl%2C+S%2E%22">Kiechl, S.</searchLink><br /><searchLink fieldCode="AR" term="%22Löscher%2C+W%2E%22">Löscher, W.</searchLink><br /><searchLink fieldCode="AR" term="%22Poewe%2C+W%2E%22">Poewe, W.</searchLink><br /><searchLink fieldCode="AR" term="%22Willeit%2C+J%2E%22">Willeit, J.</searchLink>
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22Acta+Neurologica+Scandinavica%22">Acta Neurologica Scandinavica</searchLink>. Sep2003, Vol. 108 Issue 3, p209-211. 3p.
– Name: Subject
  Label: Subjects
  Group: Su
  Data: <searchLink fieldCode="DE" term="%22Myasthenia+gravis%22">Myasthenia gravis</searchLink><br /><searchLink fieldCode="DE" term="%22Neuromuscular+diseases%22">Neuromuscular diseases</searchLink><br /><searchLink fieldCode="DE" term="%22Neurological+disorders%22">Neurological disorders</searchLink><br /><searchLink fieldCode="DE" term="%22Muscle+diseases%22">Muscle diseases</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Objectives – In Myasthenia gravis (MG) proximal limb, ocular and/or bulbar muscles are most commonly affected, whereas distal extremity muscles are typically spared. The aim of the current study was to assess the frequency of primarily distal MG in the Tyrol and to describe its clinical peculiarities. Material and methods – Over the past 20 years 84 patients with MG have undergone follow-up at the Department of Neurology of Innsbruck University. Types of presentation, clinical course and treatment response were followed over a period of 20 years (1980–2000). Results – Six of 84 MG patients showed a predominance of muscle weakness and fatigability in distal limb muscles (two at presentation, four over the later course of the illness). There was no difference between distal MG and MG with a more typical distribution of muscle weakness regarding age, gender and response to therapy. Conclusions – The case series indicates that predominantly distal presentations of otherwise typical MG are more frequent than generally assumed and should be considered in the differential diagnosis of diseases with distal limb weakness. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Acta Neurologica Scandinavica is the property of Wiley-Blackwell and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=10531445
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1034/j.1600-0404.2003.00136.x
    Languages:
      – Code: eng
        Text: English
    PhysicalDescription:
      Pagination:
        PageCount: 3
        StartPage: 209
    Subjects:
      – SubjectFull: Myasthenia gravis
        Type: general
      – SubjectFull: Neuromuscular diseases
        Type: general
      – SubjectFull: Neurological disorders
        Type: general
      – SubjectFull: Muscle diseases
        Type: general
    Titles:
      – TitleFull: Distal myasthenia gravis – frequency and clinical course in a large prospective series.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Werner, P.
      – PersonEntity:
          Name:
            NameFull: Kiechl, S.
      – PersonEntity:
          Name:
            NameFull: Löscher, W.
      – PersonEntity:
          Name:
            NameFull: Poewe, W.
      – PersonEntity:
          Name:
            NameFull: Willeit, J.
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 01
              M: 09
              Text: Sep2003
              Type: published
              Y: 2003
          Identifiers:
            – Type: issn-print
              Value: 00016314
          Numbering:
            – Type: volume
              Value: 108
            – Type: issue
              Value: 3
          Titles:
            – TitleFull: Acta Neurologica Scandinavica
              Type: main
ResultId 1