Preferred characteristics of vaginal microbicides in women with bacterial vaginosis.

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Title: Preferred characteristics of vaginal microbicides in women with bacterial vaginosis.
Authors: Cook RL (AUTHOR), Downs JS (AUTHOR), Marrazzo J (AUTHOR), Switzer GE (AUTHOR), Tanriover O (AUTHOR), Wiesenfeld H (AUTHOR), Murray PJ (AUTHOR), Hillier SL (AUTHOR)
Source: Journal of Women's Health (15409996). Aug2009, Vol. 18 Issue 8, p1163-1167. 5p.
Subjects: Anti-infective agents, Bacterial vaginitis, Diseases in women, AIDS prevention, Prevention of sexually transmitted diseases, HIV prevention, Multivariate analysis, Hygiene
Abstract: Background: Vaginal microbicides have the potential to reduce HIV/STD acquisition when used consistently. Our objectives were to determine product attributes associated with willingness to use a vaginal microbicide and whether product preferences varied according to participant characteristics. Methods: Women ( n = 408) with bacterial vaginosis (BV) were recruited as part of a randomized trial to prevent BV. Participants completed a survey interview that assessed demographic information, sexual history, and douching behavior. To assess microbicide preferences, women rated whether specific product attributes would make them more or less likely to use a vaginal microbicide. Principal components analyses revealed two major groupings for the product attribute items. We determined the relative importance of each group of product attributes and whether the importance of the different groupings varied among subgroups of women. Results: The participants' mean age was 24 years (range 14–45), 64% were black, and 74% were unmarried. Overall, participants reported being most likely to use a vaginal product with protection properties (2.54), whereas they were nearly neutral regarding side effects (0.56). The individual product attributes, could prevent BV, could prevent vaginal odor (2.72), and could prevent vaginal itching and burning (2.61), were rated similarly or slightly higher than could reduce the risk of getting an STD (2.58) or could reduce the risk of getting HIV (2.44). In multivariate analyses, protection attributes were rated significantly higher among older women and marginally higher in women with a greater number of lifetime sexual partners. Younger women were most likely to report that side effects would affect their likelihood of using the product. Conclusions: Women with BV rated potential protection features of a vaginal microbicide higher than side effects. A product's personal hygiene aspects were rated equally or more important than the product's ability to prevent HIV/STD infections. Younger women may respond to different factors that influence product acceptability and adherence. [ABSTRACT FROM AUTHOR]
Copyright of Journal of Women's Health (15409996) is the property of Mary Ann Liebert, Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.)
Database: Psychology and Behavioral Sciences Collection
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  Data: Preferred characteristics of vaginal microbicides in women with bacterial vaginosis.
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  Data: <searchLink fieldCode="AR" term="%22Cook+RL%22">Cook RL</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Downs+JS%22">Downs JS</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Marrazzo+J%22">Marrazzo J</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Switzer+GE%22">Switzer GE</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Tanriover+O%22">Tanriover O</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Wiesenfeld+H%22">Wiesenfeld H</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Murray+PJ%22">Murray PJ</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Hillier+SL%22">Hillier SL</searchLink> (AUTHOR)
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  Data: <searchLink fieldCode="JN" term="%22Journal+of+Women's+Health+%2815409996%29%22">Journal of Women's Health (15409996)</searchLink>. Aug2009, Vol. 18 Issue 8, p1163-1167. 5p.
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  Data: <searchLink fieldCode="DE" term="%22Anti-infective+agents%22">Anti-infective agents</searchLink><br /><searchLink fieldCode="DE" term="%22Bacterial+vaginitis%22">Bacterial vaginitis</searchLink><br /><searchLink fieldCode="DE" term="%22Diseases+in+women%22">Diseases in women</searchLink><br /><searchLink fieldCode="DE" term="%22AIDS+prevention%22">AIDS prevention</searchLink><br /><searchLink fieldCode="DE" term="%22Prevention+of+sexually+transmitted+diseases%22">Prevention of sexually transmitted diseases</searchLink><br /><searchLink fieldCode="DE" term="%22HIV+prevention%22">HIV prevention</searchLink><br /><searchLink fieldCode="DE" term="%22Multivariate+analysis%22">Multivariate analysis</searchLink><br /><searchLink fieldCode="DE" term="%22Hygiene%22">Hygiene</searchLink>
– Name: Abstract
  Label: Abstract
  Group: Ab
  Data: Background: Vaginal microbicides have the potential to reduce HIV/STD acquisition when used consistently. Our objectives were to determine product attributes associated with willingness to use a vaginal microbicide and whether product preferences varied according to participant characteristics. Methods: Women ( n = 408) with bacterial vaginosis (BV) were recruited as part of a randomized trial to prevent BV. Participants completed a survey interview that assessed demographic information, sexual history, and douching behavior. To assess microbicide preferences, women rated whether specific product attributes would make them more or less likely to use a vaginal microbicide. Principal components analyses revealed two major groupings for the product attribute items. We determined the relative importance of each group of product attributes and whether the importance of the different groupings varied among subgroups of women. Results: The participants' mean age was 24 years (range 14–45), 64% were black, and 74% were unmarried. Overall, participants reported being most likely to use a vaginal product with protection properties (2.54), whereas they were nearly neutral regarding side effects (0.56). The individual product attributes, could prevent BV, could prevent vaginal odor (2.72), and could prevent vaginal itching and burning (2.61), were rated similarly or slightly higher than could reduce the risk of getting an STD (2.58) or could reduce the risk of getting HIV (2.44). In multivariate analyses, protection attributes were rated significantly higher among older women and marginally higher in women with a greater number of lifetime sexual partners. Younger women were most likely to report that side effects would affect their likelihood of using the product. Conclusions: Women with BV rated potential protection features of a vaginal microbicide higher than side effects. A product's personal hygiene aspects were rated equally or more important than the product's ability to prevent HIV/STD infections. Younger women may respond to different factors that influence product acceptability and adherence. [ABSTRACT FROM AUTHOR]
– Name: AbstractSuppliedCopyright
  Label:
  Group: Ab
  Data: <i>Copyright of Journal of Women's Health (15409996) is the property of Mary Ann Liebert, Inc. and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.)
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      – Type: doi
        Value: 10.1089/jwh.2008.1067
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        Text: English
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      – SubjectFull: Anti-infective agents
        Type: general
      – SubjectFull: Bacterial vaginitis
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      – SubjectFull: Diseases in women
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      – SubjectFull: AIDS prevention
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      – SubjectFull: Prevention of sexually transmitted diseases
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      – SubjectFull: HIV prevention
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      – SubjectFull: Multivariate analysis
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      – SubjectFull: Hygiene
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      – TitleFull: Preferred characteristics of vaginal microbicides in women with bacterial vaginosis.
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              Text: Aug2009
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