International variation in the prevalence of COPD (the BOLD Study): a population-based prevalence study.
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| Title: | International variation in the prevalence of COPD (the BOLD Study): a population-based prevalence study. |
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| Authors: | Buist AS (AUTHOR), McBurnie MA (AUTHOR), Vollmer WM (AUTHOR), Gillespie S (AUTHOR), Burney P (AUTHOR), Mannino DM (AUTHOR), Menezes AM (AUTHOR), Sullivan SD (AUTHOR), Lee TA (AUTHOR), Weiss KB (AUTHOR), Jensen RL (AUTHOR), Marks GB (AUTHOR), Gulsvik A (AUTHOR), Nizankowska-Mogilnicka E (AUTHOR), BOLD Collaborative Research Group (CORPORATE AUTHOR) |
| Source: | Lancet. 9/1/2007, Vol. 370 Issue 9589, p741-750. 10p. |
| Abstract: | BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a growing cause of morbidity and mortality worldwide, and accurate estimates of the prevalence of this disease are needed to anticipate the future burden of COPD, target key risk factors, and plan for providing COPD-related health services. We aimed to measure the prevalence of COPD and its risk factors and investigate variation across countries by age, sex, and smoking status. METHODS: Participants from 12 sites (n=9425) completed postbronchodilator spirometry testing plus questionnaires about respiratory symptoms, health status, and exposure to COPD risk factors. COPD prevalence estimates based on the Global Initiative for Chronic Obstructive Lung Disease staging criteria were adjusted for the target population. Logistic regression was used to estimate adjusted odds ratios (ORs) for COPD associated with 10-year age increments and 10-pack-year (defined as the number of cigarettes smoked per day divided by 20 and multiplied by the number of years that the participant smoked) increments. Meta-analyses provided pooled estimates for these risk factors. FINDINGS: The prevalence of stage II or higher COPD was 10.1% (SE 4.8) overall, 11.8% (7.9) for men, and 8.5% (5.8) for women. The ORs for 10-year age increments were much the same across sites and for women and men. The overall pooled estimate was 1.94 (95% CI 1.80-2.10) per 10-year increment. Site-specific pack-year ORs varied significantly in women (pooled OR=1.28, 95% CI 1.15-1.42, p=0.012), but not in men (1.16, 1.12-1.21, p=0.743). INTERPRETATION: This worldwide study showed higher levels and more advanced staging of spirometrically confirmed COPD than have typically been reported. However, although age and smoking are strong contributors to COPD, they do not fully explain variations in disease prevalence-other factors also seem to be important. Although smoking cessation is becoming an increasingly urgent objective for an ageing worldwide population, a better understanding of other factors that contribute to COPD is crucial to assist local public-health officials in developing the best possible primary and secondary prevention policies for their regions. [ABSTRACT FROM AUTHOR] |
| Copyright of Lancet is the property of Lancet and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 105642863 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: International variation in the prevalence of COPD (the BOLD Study): a population-based prevalence study. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Buist+AS%22">Buist AS</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22McBurnie+MA%22">McBurnie MA</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Vollmer+WM%22">Vollmer WM</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Gillespie+S%22">Gillespie S</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Burney+P%22">Burney P</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Mannino+DM%22">Mannino DM</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Menezes+AM%22">Menezes AM</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Sullivan+SD%22">Sullivan SD</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Lee+TA%22">Lee TA</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Weiss+KB%22">Weiss KB</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Jensen+RL%22">Jensen RL</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Marks+GB%22">Marks GB</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Gulsvik+A%22">Gulsvik A</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Nizankowska-Mogilnicka+E%22">Nizankowska-Mogilnicka E</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22BOLD+Collaborative+Research+Group%22">BOLD Collaborative Research Group</searchLink> (CORPORATE AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Lancet%22">Lancet</searchLink>. 9/1/2007, Vol. 370 Issue 9589, p741-750. 10p. – Name: Abstract Label: Abstract Group: Ab Data: BACKGROUND: Chronic obstructive pulmonary disease (COPD) is a growing cause of morbidity and mortality worldwide, and accurate estimates of the prevalence of this disease are needed to anticipate the future burden of COPD, target key risk factors, and plan for providing COPD-related health services. We aimed to measure the prevalence of COPD and its risk factors and investigate variation across countries by age, sex, and smoking status. METHODS: Participants from 12 sites (n=9425) completed postbronchodilator spirometry testing plus questionnaires about respiratory symptoms, health status, and exposure to COPD risk factors. COPD prevalence estimates based on the Global Initiative for Chronic Obstructive Lung Disease staging criteria were adjusted for the target population. Logistic regression was used to estimate adjusted odds ratios (ORs) for COPD associated with 10-year age increments and 10-pack-year (defined as the number of cigarettes smoked per day divided by 20 and multiplied by the number of years that the participant smoked) increments. Meta-analyses provided pooled estimates for these risk factors. FINDINGS: The prevalence of stage II or higher COPD was 10.1% (SE 4.8) overall, 11.8% (7.9) for men, and 8.5% (5.8) for women. The ORs for 10-year age increments were much the same across sites and for women and men. The overall pooled estimate was 1.94 (95% CI 1.80-2.10) per 10-year increment. Site-specific pack-year ORs varied significantly in women (pooled OR=1.28, 95% CI 1.15-1.42, p=0.012), but not in men (1.16, 1.12-1.21, p=0.743). INTERPRETATION: This worldwide study showed higher levels and more advanced staging of spirometrically confirmed COPD than have typically been reported. However, although age and smoking are strong contributors to COPD, they do not fully explain variations in disease prevalence-other factors also seem to be important. Although smoking cessation is becoming an increasingly urgent objective for an ageing worldwide population, a better understanding of other factors that contribute to COPD is crucial to assist local public-health officials in developing the best possible primary and secondary prevention policies for their regions. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Lancet is the property of Lancet and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
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| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1016/s0140-6736(07)61377-4 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 10 StartPage: 741 Titles: – TitleFull: International variation in the prevalence of COPD (the BOLD Study): a population-based prevalence study. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Buist AS – PersonEntity: Name: NameFull: McBurnie MA – PersonEntity: Name: NameFull: Vollmer WM – PersonEntity: Name: NameFull: Gillespie S – PersonEntity: Name: NameFull: Burney P – PersonEntity: Name: NameFull: Mannino DM – PersonEntity: Name: NameFull: Menezes AM – PersonEntity: Name: NameFull: Sullivan SD – PersonEntity: Name: NameFull: Lee TA – PersonEntity: Name: NameFull: Weiss KB – PersonEntity: Name: NameFull: Jensen RL – PersonEntity: Name: NameFull: Marks GB – PersonEntity: Name: NameFull: Gulsvik A – PersonEntity: Name: NameFull: Nizankowska-Mogilnicka E – PersonEntity: Name: NameFull: BOLD Collaborative Research Group IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 09 Text: 9/1/2007 Type: published Y: 2007 Identifiers: – Type: issn-print Value: 01406736 Numbering: – Type: volume Value: 370 – Type: issue Value: 9589 Titles: – TitleFull: Lancet Type: main |
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