A randomized intervention trial to reduce the lending of used injection equipment among injection drug users infected with hepatitis C.
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| Title: | A randomized intervention trial to reduce the lending of used injection equipment among injection drug users infected with hepatitis C. |
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| Authors: | Latka MH (AUTHOR), Hagan H (AUTHOR), Kapadia F (AUTHOR), Golub ET (AUTHOR), Bonner S (AUTHOR), Campbell JV (AUTHOR), Coady MH (AUTHOR), Garfein RS (AUTHOR), Pu M (AUTHOR), Thomas DL (AUTHOR), Thiel TK (AUTHOR), Strathdee SA (AUTHOR) |
| Source: | American Journal of Public Health. May2008, Vol. 98 Issue 5, p853-861. 9p. |
| Subjects: | Hepatitis C, Intravenous drug abusers, Needle sharing, Health behavior, Prevention of communicable diseases |
| Geographic Terms: | United States |
| Abstract: | OBJECTIVES: We evaluated the efficacy of a peer-mentoring behavioral intervention designed to reduce risky distributive injection practices (e.g., syringe lending, unsafe drug preparation) among injection drug users with hepatitis C virus (HCV) infection. METHODS: A randomized trial with a time-equivalent attention-control group was conducted among 418 HCV-positive injection drug users aged 18 to 35 years in 3 US cities. Participants reported their injection-related behaviors at baseline and at 3- and 6-month follow-ups. RESULTS: Compared with the control group, intervention-group participants were less likely to report distributive risk behaviors at 3 months (odds ratio [OR]=0.46; 95% confidence interval [CI]=0.27, 0.79) and 6 months (OR=0.51; 95% CI=0.31, 0.83), a 26% relative risk reduction, but were no more likely to cite their HCV-positive status as a reason for refraining from syringe lending. Effects were strongest among intervention-group participants who had known their HCV-positive status for at least 6 months. Peer mentoring and self-efficacy were significantly increased among intervention-group participants, and intervention effects were mediated through improved self-efficacy. CONCLUSIONS: This behavioral intervention reduced unsafe injection practices that may propagate HCV among injection drug users. [ABSTRACT FROM AUTHOR] |
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| Database: | Psychology and Behavioral Sciences Collection |
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| Abstract: | OBJECTIVES: We evaluated the efficacy of a peer-mentoring behavioral intervention designed to reduce risky distributive injection practices (e.g., syringe lending, unsafe drug preparation) among injection drug users with hepatitis C virus (HCV) infection. METHODS: A randomized trial with a time-equivalent attention-control group was conducted among 418 HCV-positive injection drug users aged 18 to 35 years in 3 US cities. Participants reported their injection-related behaviors at baseline and at 3- and 6-month follow-ups. RESULTS: Compared with the control group, intervention-group participants were less likely to report distributive risk behaviors at 3 months (odds ratio [OR]=0.46; 95% confidence interval [CI]=0.27, 0.79) and 6 months (OR=0.51; 95% CI=0.31, 0.83), a 26% relative risk reduction, but were no more likely to cite their HCV-positive status as a reason for refraining from syringe lending. Effects were strongest among intervention-group participants who had known their HCV-positive status for at least 6 months. Peer mentoring and self-efficacy were significantly increased among intervention-group participants, and intervention effects were mediated through improved self-efficacy. CONCLUSIONS: This behavioral intervention reduced unsafe injection practices that may propagate HCV among injection drug users. [ABSTRACT FROM AUTHOR] |
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| ISSN: | 00900036 |
| DOI: | 10.2105/AJPH.2007.113415 |
