The role of botulinum toxin injections in the management of muscle overactivity of the lower limb.
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| Title: | The role of botulinum toxin injections in the management of muscle overactivity of the lower limb. |
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| Authors: | Gracies J (AUTHOR), Singer BJ (AUTHOR), Dunne JW (AUTHOR) |
| Source: | Disability & Rehabilitation. Dec2007, Vol. 29 Issue 23, p1789-1805. 17p. |
| Abstract: | Muscle overactivity is common in patients with adult onset central nervous system damage. It can produce significant disablement in conjunction with other impairments such as adaptive soft tissue shortening and loss of muscle strength. Muscle overactivity is not evenly distributed throughout the body; across joints there is frequently imbalance between agonist and antagonist, producing abnormal joint postures and movement patterns. Due to the asymmetric nature of the abnormal activity across joints, in general we recommend local treatment targeting the more overactive of the two agonists, rather than systemic treatment. Considerable experience with the use of botulinum toxin, both serotypes A and B, in the treatment of muscle overactivity has been accumulated in the last two decades through pragmatic clinical practice and open label studies, supported by an increasing number of randomized controlled trials. In most cases, it is important to use botulinum toxin injection for treatment of muscle overactivity in the setting of wider rehabilitation goals and interventions. Focal and partial blocks with botulinum toxin should be used as a component of a general neurorehabilitation programme rather than as an alternative to other treatments. We review the evidence supporting the use of botulinum toxin to treat muscle overactivity in the lower limb, present practical guidelines on when and how to use botulinum toxin and provide direction for future research. [ABSTRACT FROM AUTHOR] |
| Copyright of Disability & Rehabilitation is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 105864922 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: The role of botulinum toxin injections in the management of muscle overactivity of the lower limb. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Gracies+J%22">Gracies J</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Singer+BJ%22">Singer BJ</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Dunne+JW%22">Dunne JW</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Disability+%26+Rehabilitation%22">Disability & Rehabilitation</searchLink>. Dec2007, Vol. 29 Issue 23, p1789-1805. 17p. – Name: Abstract Label: Abstract Group: Ab Data: Muscle overactivity is common in patients with adult onset central nervous system damage. It can produce significant disablement in conjunction with other impairments such as adaptive soft tissue shortening and loss of muscle strength. Muscle overactivity is not evenly distributed throughout the body; across joints there is frequently imbalance between agonist and antagonist, producing abnormal joint postures and movement patterns. Due to the asymmetric nature of the abnormal activity across joints, in general we recommend local treatment targeting the more overactive of the two agonists, rather than systemic treatment. Considerable experience with the use of botulinum toxin, both serotypes A and B, in the treatment of muscle overactivity has been accumulated in the last two decades through pragmatic clinical practice and open label studies, supported by an increasing number of randomized controlled trials. In most cases, it is important to use botulinum toxin injection for treatment of muscle overactivity in the setting of wider rehabilitation goals and interventions. Focal and partial blocks with botulinum toxin should be used as a component of a general neurorehabilitation programme rather than as an alternative to other treatments. We review the evidence supporting the use of botulinum toxin to treat muscle overactivity in the lower limb, present practical guidelines on when and how to use botulinum toxin and provide direction for future research. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Disability & Rehabilitation is the property of Taylor & Francis Ltd and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=105864922 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1080/09638280701568437 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 17 StartPage: 1789 Titles: – TitleFull: The role of botulinum toxin injections in the management of muscle overactivity of the lower limb. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Gracies J – PersonEntity: Name: NameFull: Singer BJ – PersonEntity: Name: NameFull: Dunne JW IsPartOfRelationships: – BibEntity: Dates: – D: 15 M: 12 Text: Dec2007 Type: published Y: 2007 Identifiers: – Type: issn-print Value: 09638288 Numbering: – Type: volume Value: 29 – Type: issue Value: 23 Titles: – TitleFull: Disability & Rehabilitation Type: main |
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