Brief report: abnormal association between the thalamus and brain size in Asperger's disorder.
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| Title: | Brief report: abnormal association between the thalamus and brain size in Asperger's disorder. |
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| Authors: | Hardan AY (AUTHOR), Girgis RR (AUTHOR), Adams J (AUTHOR), Gilbert AR (AUTHOR), Melhem NM (AUTHOR), Keshavan MS (AUTHOR), Minshew NJ (AUTHOR) |
| Source: | Journal of Autism & Developmental Disorders. Feb2008, Vol. 38 Issue 2, p390-394. 5p. |
| Abstract: | The objective of this study was to examine the relationship between thalamic volume and brain size in individuals with Asperger's disorder (ASP). Volumetric measurements of the thalamus were performed on MRI scans obtained from 12 individuals with ASP (age range: 10-35 years) and 12 healthy controls (age range: 9-33 years). A positive correlation was found between total brain volume and thalamic size in controls, but not in ASP subjects. This occurred in the absence of differences in mean thalamic volumes between the study groups. Findings from this investigation point to an abnormal relationship between the thalamus and its projection areas in ASP and are consistent with similar studies in autism, supporting that these disorders are qualitatively similar and possibly quantitatively different. [ABSTRACT FROM AUTHOR] |
| Copyright of Journal of Autism & Developmental Disorders is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 105913467 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: Brief report: abnormal association between the thalamus and brain size in Asperger's disorder. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Hardan+AY%22">Hardan AY</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Girgis+RR%22">Girgis RR</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Adams+J%22">Adams J</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Gilbert+AR%22">Gilbert AR</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Melhem+NM%22">Melhem NM</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Keshavan+MS%22">Keshavan MS</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Minshew+NJ%22">Minshew NJ</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Journal+of+Autism+%26+Developmental+Disorders%22">Journal of Autism & Developmental Disorders</searchLink>. Feb2008, Vol. 38 Issue 2, p390-394. 5p. – Name: Abstract Label: Abstract Group: Ab Data: The objective of this study was to examine the relationship between thalamic volume and brain size in individuals with Asperger's disorder (ASP). Volumetric measurements of the thalamus were performed on MRI scans obtained from 12 individuals with ASP (age range: 10-35 years) and 12 healthy controls (age range: 9-33 years). A positive correlation was found between total brain volume and thalamic size in controls, but not in ASP subjects. This occurred in the absence of differences in mean thalamic volumes between the study groups. Findings from this investigation point to an abnormal relationship between the thalamus and its projection areas in ASP and are consistent with similar studies in autism, supporting that these disorders are qualitatively similar and possibly quantitatively different. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Journal of Autism & Developmental Disorders is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=105913467 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s10803-007-0385-1 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 5 StartPage: 390 Titles: – TitleFull: Brief report: abnormal association between the thalamus and brain size in Asperger's disorder. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Hardan AY – PersonEntity: Name: NameFull: Girgis RR – PersonEntity: Name: NameFull: Adams J – PersonEntity: Name: NameFull: Gilbert AR – PersonEntity: Name: NameFull: Melhem NM – PersonEntity: Name: NameFull: Keshavan MS – PersonEntity: Name: NameFull: Minshew NJ IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 02 Text: Feb2008 Type: published Y: 2008 Identifiers: – Type: issn-print Value: 01623257 Numbering: – Type: volume Value: 38 – Type: issue Value: 2 Titles: – TitleFull: Journal of Autism & Developmental Disorders Type: main |
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