A family genetic study of autism associated with profound mental retardation.
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| Title: | A family genetic study of autism associated with profound mental retardation. |
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| Authors: | Starr E (AUTHOR), Berument SK (AUTHOR), Pickles A (AUTHOR), Tomlins M (AUTHOR), Bailey A (AUTHOR), Papanikolaou K (AUTHOR), Rutter M (AUTHOR) |
| Source: | Journal of Autism & Developmental Disorders. Feb2001, Vol. 31 Issue 1, p89-96. 8p. |
| Abstract: | We sought to determine if the family loading for either the broader autism phenotype or for cognitive impairment differed according to whether or not autism was accompanied by severe mental retardation. The sample comprised 47 probands with autism meeting ICD-10 criteria, as assessed by the Autism Diagnostic Interview and the Autism Diagnostic Observation Schedule. Family history interview and findings were compared with those for the higher IQ autism and Down syndrome samples in the Bolton et al. (1994) study. The familial loading for autism and for the broader phenotype was closely comparable to that in the study of higher IQ autism, and different from that for Down syndrome. The family loading for scholastic achievement difficulties was slightly, but significantly, higher when autism was accompanied by severe retardation. [ABSTRACT FROM AUTHOR] |
| Copyright of Journal of Autism & Developmental Disorders is the property of Springer Nature and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Links: – Type: pdflink Text: Availability: 0 |
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| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 106080084 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=106080084 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1023/a:1005669915105 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 8 StartPage: 89 Titles: – TitleFull: A family genetic study of autism associated with profound mental retardation. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Starr E – PersonEntity: Name: NameFull: Berument SK – PersonEntity: Name: NameFull: Pickles A – PersonEntity: Name: NameFull: Tomlins M – PersonEntity: Name: NameFull: Bailey A – PersonEntity: Name: NameFull: Papanikolaou K – PersonEntity: Name: NameFull: Rutter M IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 02 Text: Feb2001 Type: published Y: 2001 Identifiers: – Type: issn-print Value: 01623257 Numbering: – Type: volume Value: 31 – Type: issue Value: 1 Titles: – TitleFull: Journal of Autism & Developmental Disorders Type: main |
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