Birth weight, postnatal growth, and risk for high blood pressure at 7 years of age: results from the Collaborative Perinatal Project.
Saved in:
| Title: | Birth weight, postnatal growth, and risk for high blood pressure at 7 years of age: results from the Collaborative Perinatal Project. |
|---|---|
| Authors: | Hemachandra AH (AUTHOR), Howards PP (AUTHOR), Furth SL (AUTHOR), Klebanoff MA (AUTHOR) |
| Source: | Pediatrics. Jun2007, Vol. 119 Issue 6, pe1264-70. 1p. |
| Abstract: | OBJECTIVE: A physiologic predisposition toward hypertension is theorized to result from the combination of intrauterine growth restriction followed by rapid catch-up growth. The objective of this study was to evaluate the effects of birth weight and weight gain during childhood on the risk for high blood pressure in childhood and to identify discrete periods of catch-up growth that put children with intrauterine growth restriction at increased risk for the development of high blood pressure later in life. METHODS: The US Collaborative Perinatal Project (1959-1974) studied 55,908 pregnancies in an observational cohort at 12 medical centers in the United States and followed the offspring through 7 years of age. All white or black children who were born at term and completed the follow-up without kidney or heart disease were included in this posthoc analysis. z scores were calculated for weight at birth, 4 months, 1 year, 4 years, and 7 years on the basis of study means and SD. Changes in z scores were calculated for each interval. RESULTS: Each 1-kg increase in birth weight increased the odds for high systolic blood pressure by 2.19 and high diastolic blood pressure by 1.82 when race and change in weight z scores were also included in the regression model. An increase in weight z score of 1 SD above the previous weight z score increased the odds for high systolic blood pressure at 7 years by 1.65 (birth to 4 months), 1.79 (4 months to 1 year), 1.71 (1-4 years), and 1.94 (4-7 years) in the full model. White race increased the odds for high systolic blood pressure by 1.51. CONCLUSIONS: In this large biracial US cohort, infants who were small for gestational age were not at increased risk for high blood pressure at 7 years of age. However, children who crossed weight percentiles upward during early childhood did demonstrate an increased risk. [ABSTRACT FROM AUTHOR] |
| Copyright of Pediatrics is the property of American Academy of Pediatrics and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract. (Copyright applies to all Abstracts.) | |
| Database: | Psychology and Behavioral Sciences Collection |
| FullText | Text: Availability: 0 |
|---|---|
| Header | DbId: pbh DbLabel: Psychology and Behavioral Sciences Collection An: 106135416 AccessLevel: 6 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Birth weight, postnatal growth, and risk for high blood pressure at 7 years of age: results from the Collaborative Perinatal Project. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AR" term="%22Hemachandra+AH%22">Hemachandra AH</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Howards+PP%22">Howards PP</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Furth+SL%22">Furth SL</searchLink> (AUTHOR)<br /><searchLink fieldCode="AR" term="%22Klebanoff+MA%22">Klebanoff MA</searchLink> (AUTHOR) – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22Pediatrics%22">Pediatrics</searchLink>. Jun2007, Vol. 119 Issue 6, pe1264-70. 1p. – Name: Abstract Label: Abstract Group: Ab Data: OBJECTIVE: A physiologic predisposition toward hypertension is theorized to result from the combination of intrauterine growth restriction followed by rapid catch-up growth. The objective of this study was to evaluate the effects of birth weight and weight gain during childhood on the risk for high blood pressure in childhood and to identify discrete periods of catch-up growth that put children with intrauterine growth restriction at increased risk for the development of high blood pressure later in life. METHODS: The US Collaborative Perinatal Project (1959-1974) studied 55,908 pregnancies in an observational cohort at 12 medical centers in the United States and followed the offspring through 7 years of age. All white or black children who were born at term and completed the follow-up without kidney or heart disease were included in this posthoc analysis. z scores were calculated for weight at birth, 4 months, 1 year, 4 years, and 7 years on the basis of study means and SD. Changes in z scores were calculated for each interval. RESULTS: Each 1-kg increase in birth weight increased the odds for high systolic blood pressure by 2.19 and high diastolic blood pressure by 1.82 when race and change in weight z scores were also included in the regression model. An increase in weight z score of 1 SD above the previous weight z score increased the odds for high systolic blood pressure at 7 years by 1.65 (birth to 4 months), 1.79 (4 months to 1 year), 1.71 (1-4 years), and 1.94 (4-7 years) in the full model. White race increased the odds for high systolic blood pressure by 1.51. CONCLUSIONS: In this large biracial US cohort, infants who were small for gestational age were not at increased risk for high blood pressure at 7 years of age. However, children who crossed weight percentiles upward during early childhood did demonstrate an increased risk. [ABSTRACT FROM AUTHOR] – Name: AbstractSuppliedCopyright Label: Group: Ab Data: <i>Copyright of Pediatrics is the property of American Academy of Pediatrics and its content may not be copied or emailed to multiple sites without the copyright holder's express written permission. Additionally, content may not be used with any artificial intelligence tools or machine learning technologies. However, users may print, download, or email articles for individual use. This abstract may be abridged. No warranty is given about the accuracy of the copy. Users should refer to the original published version of the material for the full abstract.</i> (Copyright applies to all Abstracts.) |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=pbh&AN=106135416 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1542/peds.2005-2486 Languages: – Code: eng Text: English PhysicalDescription: Pagination: PageCount: 1 StartPage: e1264 Titles: – TitleFull: Birth weight, postnatal growth, and risk for high blood pressure at 7 years of age: results from the Collaborative Perinatal Project. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Hemachandra AH – PersonEntity: Name: NameFull: Howards PP – PersonEntity: Name: NameFull: Furth SL – PersonEntity: Name: NameFull: Klebanoff MA IsPartOfRelationships: – BibEntity: Dates: – D: 01 M: 06 Text: Jun2007 Type: published Y: 2007 Identifiers: – Type: issn-print Value: 00314005 Numbering: – Type: volume Value: 119 – Type: issue Value: 6 Titles: – TitleFull: Pediatrics Type: main |
| ResultId | 1 |
